A short route to L-iduronic acid building blocks for the syntheses of heparin-like disaccharides

Tetrahedron Letters

Volumn 44, Issue 42, 2003, Pages 7767-7770

  Ke, Weijun ^a   Whitfield, Dennis M ^a   Gill, Manjinder ^a   Larocque, Suzon ^a   Yu, Siu Hong ^a  

^a NATIONAL RESEARCH COUNCIL CANADA   (Canada)

Author keywords

Carbohydrates; Disaccharides; Glycosylations; Heparin

Indexed keywords

1,2 O ISOPROPYLIDENE 6,3 DEXTRO GLUCURONOLACTONE; DISACCHARIDE; HEPARIN; HYDROXYL GROUP; IDURONIC ACID; LACTONE DERIVATIVE; OLIGOSACCHARIDE; UNCLASSIFIED DRUG;

ARTICLE; CARBOHYDRATE SYNTHESIS; DRUG SULFATION; DRUG SYNTHESIS; GLYCOSYLATION; HYDROGENATION; NUCLEAR OVERHAUSER EFFECT; PROTON NUCLEAR MAGNETIC RESONANCE; SAPONIFICATION;

EID: 0141682267     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2003.08.092     Document Type: Article

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35. 2O): δ 5.13 (br s, 1H), 4.97 (d, J=3.3 Hz, 1H), 4.72 (d, J=2.3 Hz, 1H), 4.25 (br t, 1H), 4.04 (br t, 1H), 4.01 (br t, 1H), 3.91 (m, 2H), 3.84 (br t, 1H), 3.82 (br t, 1H), 3.74 (br t, 1H), 3.45 (s, 3H), 3.25 (dd, J=3.3, 10.1 Hz, 1H).
36. 2O): δ 5.16 (br s, 1H), 5. 04 (d, J=3.5 Hz, 1H), 4.74 (d, J=2.7 Hz, 1H), 4.34 (br t, 2H), 4.26 (br t, 1H), 4.05 (br t, 1H), 4.00 (m, 2H), 3.75 (br t, 1H), 3.69 (br t, 1H), 3.44 (s, 3H), 3.30 (dd, J=3.5, 9.9 Hz, 1H).
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