A synthetic heparan sulfate pentasaccharide, exclusively containing L-iduronic acid, displays higher affinity for FGF-2 than its D-glucuronic acid-containing isomers

Bioorganic and Medicinal Chemistry

Volumn 7, Issue 8, 1999, Pages 1567-1580

  Kovensky, José ^a,d   Duchaussoy, Philippe ^b   Bono, Françoise ^b   Salmivirta, Markku ^c   Sizun, Philippe ^b   Herbert, Jean Marc ^b   Petitou, Maurice ^b   Sinaÿ, Pierre ^a  

^a ECOLE NORMALE SUPÉRIEURE   (France)

^b SANOFI   (France)

^c UPPSALA UNIVERSITY   (Sweden)

^d UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

Carbohydrates; Glycosylation; Growth factors; Heparan sulfate

Indexed keywords

FIBROBLAST GROWTH FACTOR 2; HEPARAN SULFATE; PENTASACCHARIDE;

AORTA; ARTICLE; BINDING AFFINITY; BINDING SITE; CHEMICAL STRUCTURE; CONTROLLED STUDY; HUMAN; HUMAN CELL; INTESTINE; SYNTHESIS;

AORTA; BINDING SITES; CARBOHYDRATE SEQUENCE; CELL DIVISION; CELLS, CULTURED; FIBROBLAST GROWTH FACTOR 2; GLUCURONIC ACID; HEPARITIN SULFATE; HUMANS; IDURONIC ACID; ISOMERISM; MOLECULAR SEQUENCE DATA; MUSCLE, SMOOTH, VASCULAR; OLIGOSACCHARIDES;

EID: 0032790340     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(99)00106-6     Document Type: Article

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