Iontophoretic in vivo transdermal delivery of β-blockers in hairless rats and reduced skin irritation by liposomal formulation

Pharmaceutical Research

Volumn 20, Issue 9, 2003, Pages 1496-1501

  Conjeevaram, Rajkumar ^a,b   Chaturvedula, Ayyappa ^a   Betageri, Guru V ^c   Sunkara, Gangadhar ^d   Banga, Ajay K ^a  

^a MERCER UNIVERSITY   (United States)

^b Solvay Pharmaceuticals Inc   (Netherlands)

^c WESTERN UNIVERSITY OF HEALTH SCIENCES   (United States)

^d NOVARTIS PHARMA AG   (Switzerland)

Author keywords

blockers; Iontophoresis; Liposomes; Propranolol; Timolol; Transdermal

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; LIPOSOME; METOPROLOL; OXPRENOLOL; PROPRANOLOL; SOTALOL; TIMOLOL MALEATE;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; CANNULATION; CONTROLLED STUDY; DEVICE; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG PENETRATION; ENANTIOMER; FILM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDRATION; IN VIVO STUDY; IONTOPHORESIS; JUGULAR VEIN; NONHUMAN; PRIORITY JOURNAL; RAT; RAT STRAIN; SKIN IRRITATION; STATISTICAL SIGNIFICANCE;

ADMINISTRATION, CUTANEOUS; ADRENERGIC BETA-ANTAGONISTS; ANIMALS; BIOLOGICAL TRANSPORT; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG CARRIERS; INJECTIONS, INTRAVENOUS; IONTOPHORESIS; IRRITANTS; LIPOSOMES; METOPROLOL; OXPRENOLOL; PROPRANOLOL; RATS; SKIN; SKIN ABSORPTION; SOTALOL; STEREOISOMERISM; TIMOLOL;

EID: 0141677978     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1025726715063     Document Type: Article

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