Histopathological study on the PTHrP-induced incisor lesions in rats

Toxicologic Pathology

Volumn 31, Issue 5, 2003, Pages 480-485

  Kato, Atsuhiko ^a   Suzuki, Masami ^a   Karasawa, Yayoi ^a   Sugimoto, Tetsuro ^a   Doi, Kunio ^b  

^a CHUGAI PHARMACEUTICAL CO LTD   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

Dentinal lesion; HHM model; Incisor fracture; LC 6; Odontoblast; PTHrP; Tooth lesions

Indexed keywords

PARATHYROID HORMONE RELATED PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIFICATION; CANCER; CELL STRAIN; CELL STRAIN LC 6; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DENTIN; DISEASE ASSOCIATION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMORAL HYPERCALCEMIA OF MALIGNANCY; HYPERCALCEMIA; INCISOR; MALE; MANDIBLE; NONHUMAN; ODONTOBLAST; PATHOGENESIS; PRIORITY JOURNAL; RAT; RAT STRAIN; TONGUE; TOOTH FRACTURE;

ANIMALS; CELL LINE, TUMOR; CELL TRANSPLANTATION; DENTIN; INCISOR; MALE; MODELS, BIOLOGICAL; ODONTOBLASTS; PARATHYROID HORMONE-RELATED PROTEIN; RATS; RATS, NUDE; TIME FACTORS;

ANIMALIA;

EID: 0141676209     PISSN: 01926233     EISSN: None     Source Type: Journal    
DOI: 10.1080/01926230309788     Document Type: Article

References (41)

1. Adatia AK (1975). The effect of cyclophosphomide on odontogenesis in the rat. Arch Oral Biol 20: 141-144.
2. Adkins KF (1972). The effect of actinomycin D on differentiation of the odontoblasts in the rat. Archs Oral Biol 17: 323-328.
3. Bishop MA, Boyde A (1986). Distribution of capillaries in relation to the life cycle of odontoblasts in the rat incisor. Ant Embryol 175: 189-198.
4. Chung U, Schipani E, McMahon AP, Kronenberg HM (2001). Indian hedge-hog couples chondrogenesis to osteogenesis in endchondral bone development. J Clin Invest 107: 259-304.
5. Dahl JE (1984). Influence of doxorubicin on rat incisor mesenchymal cells. Scan J Dent Res 92: 6-13.
6. Dahl JE (1985). Immediate and delayed effects of repeated doxorubicin injections on rat incisor mesenchymal cells. Acta Odontol Scand 43: 155-162.
7. Dahl JE, Koppang HS (1985). Renewal and migration of rat incisor mesenchymal cells after doxorubicin administration. Acta Odontol Scand 43: 97-102.
8. Endo K, Katsumata K, Iguchi H, Kubodera N, Teramoto T, Ikeda K, Fujita T, Ogata E (1998). Effect of combination treatment with a vitamin D analog (OCT) and a bisphosphonate (AHPrBP) in a nude mouse model of cancer-associated hypercalcemia. J Bone Miner Res 13: 1378-1383.
9. Ferguson CM, Miclau T, Hu D, Alpern E, Helms JA (1998). Common molecular pathways in skeletal morphogenesis and repair. Ann NY Acad Sci 857: 33-42.
10. Haq M, Kremer R, Goltzman D, Rabbani S (1993). A vitamin D analogue (EB 1089) inhibits parathyroid hormone-related peptide production and prevents the development of malignancy-associated hypercalcemia in vivo. J Clin Invest 91: 2416-2422.
11. Harris LJ, Innes JRM (1931). Mode of action of vitamin D. Studies on hypervitaminnosis-D. Biochem J 25: 367-390.
12. Karim AC, Eddy EL (1984). A light and electron microscopic study of osteodentin formation in the rat incisor after adriamycin administration. Am J Anat 169: 207-219.
13. Koppang HS (1973). Autoradiographic investigation on the effect of cyclophosphamide on dentinogenesis of the rat incisor. Scand J Dent Res 81: 397-405.
14. Kuijpers HMM, van de Kooij JA, Slootweg JP (1996). The rat incisor in toxicologic pathology. Toxicol Pathol 24: 346-360.
15. Kukreja CS, Rosol JT, Wimbiscus AS, Shevrin HD, Grill V, Barengolts IE, Martin JT (1990). Tumor resection and antibodies to parathyroid hormone-related protein cause similar changes on bone histomorphometry in hypercalcemia of cancer. Endocrinology 127: 305-310.
16. Liu B, Amizuka N, Goltzman D, Rabbani AS (1995). Inhibition of processing of parathyroid hormone-related peptide by anti-sense furin: Effect in vitro and in vivo on rat leydig (H-500) tumor cells. Int J Cancer 63: 276-281.
17. Lundgren T, Stenport V, Linde AW (1998). Parathyroid hormone (1-34) receptor-binding and second-messenger response in rat incisor odontoblast. Calcif Tissue Int 62: 255-259.
18. Mikkelsen HB (1978). Acute and protracted effects of vinblastine on odontoblasts and dentinodgenesis in rat incisors. Scand J Dent Res 86: 313-324.
19. Moule AJ, Young WG, Adkins KF (1993). Early cellular events in an actinomycin D-created dentin niche in the rat incisor. J Oral Pathol Med 22; 159-167.
20. Nogueira TO, Stent T, Koppang HS (1981). Colchicine's effects on rat incisor odontoblasts and dentinogenesis. J Dent Res 89: 48-58.
21. Onuma E, Saito H, Azuma Y, Shimizu N, Tsunenari T, Sato K, Takahashi S, Ogata E (2000). The possibility of utilizing humanized anti-PTHrP antibody as an anti-HHM/cachexia agent. 91st American Association for Cancer Research (AACR), San Francisco.
22. Philbrick MW, Dreyer EB, Nakchbandi AI, Karaplis CA (1998). Parathyroid hormone-related protein is required for tooth eruption. Proc Natl Acad Sci USA 95: 11846-11851.
23. Roskams T, Desmet V (1997). Parathyroid-hormone-related peptides. A new class of multifunctional proteins. Am J Pathol 150: 779-785.
24. Sato K, Yamakawa Y, Shizume K, Satoh T, Nohtomi K, Demmura H, Akatsu T, Nagata N, Kasahara T, Ohkawa H, Ohsumi K (1993). Pasive immunization with anti-parathyroid hormone-related protein monoclonal antibody markedly prolongs survival time of hypercalcemic nude mice bearing transplanted human PTHrP-producing tumors. J Bone Miner Res 8: 849-860.
25. Schipani E, Lanske B, Hunzelman J, Luz A, Kovacs CS, Lee K, Pirro A, Kronenberg HM, Jüppner H (1997). Targeted expression of constitutively active receptors for parathyroid hormone and parathyroid hormone-related peptide delays endchondral bone formation and rescues mice that lack parathyroid hormon-related peptide. Proc Natl Acad Sci USA 94: 13689-13694.
26. Schour I, Massler M (1934). The teeth. In: The Rat in Laboratory Investigation. 2nd ed, Grffith JQ, Farris EJ (eds). J.B. Lippincott, Philadelphia, pp 104-165.
27. Stene T (1978). Effect of vincristine on odontoblasts in rat incisor. ScandJ Dent Res 86: 346-356.
28. Stene T (1979). Vincristine's effect on deninogenesis in rat incisor. Scand J Dent Res 87: 39-49.
29. Stent T, Koppang HS (1976). The effect of vincristine on dentinogenesis in rat incisor. Scand J Dent Res 84: 342-344.
30. Stent T, Koppang HS (1980). Autoradiographic investigation of proliferative responses in rat incisor pulp after vincristine administration. Scand J Dent Res 88: 96-103.
31. Strewler JG (2000). The physiology of parathyroid hormone-related protein. N Engl J Med 342: 177-185.
32. Tabata S, Wada K, Semba T (1993). Fate of odontoblasts and blood capillaries in the incisal resion of the rat incisor pulp. Anat Rec 235: 12-20.
33. Takaori-Kondo A, Imada K, Yamamoto I, Kunitomi A, Numata Y, Sawada H, Uchiyama T (1998). Parathyroid hormone-related protein-induced hypercalcemia in SCID mice engrafted with Adult T-cell Leukemia cells. Blood 91: 4747-4751.
34. Tashiro T, Inaba M, Kobayashi T, Sakurai Y, Maruo K, Ohnishi Y, Ueyama Y, Nomura T (1989). Responsiveness of human lung cancer/nude mouse to antitumor agents in a model using clinically equivalent doses. Cancer Chemother Pharmacol 24: 187-192.
35. Tenorio D, Hughes FJ (1996). An immunohistochemical investigation of the expression of parathyroid hormone receptors in rat cementoblasts. Arch Oral Biol 41: 299-305.
36. Vortkamp A, Pathi S, Peretti GM, Caruso EM, Zaleske DJ, Tabin CJ (1998). Recapitulation of signals regulating embryonic bone formation during postnatal growth and in fracture repair. Mech Dev 71: 65-76.
37. Weir EC, Philbrick WM, Amling M, Neff LA, Baron R, Broadus AE (1996). Targeted overexpression of parathyroid hormone-related peptide in chondrocytes causes chondrodysplasia and delayed endochondral bone formation. Proc Natl Acad Sci USA 93: 10240-10245.
38. Wysolmerski JJ, Broadus AE, Zhou J, Fuchs E, Milstone LM, Philbrick WM (1994). Overexpression of parathyroid hormone-related protein in skin of transgenic mice interferes with hair follicle development. Proc Natl Acad Sci USA 91: 1133-1137.
39. Wysolmerski JJ, Mccaughem-Carucci JF, Daifotis AG, Broadus AE, Philbrick WM (1995). Overexpression of parathyroid hormone-related protein or parathyroid hormone in transgenic mice impairs branching morphogenesis during mammary gland development. Development 121: 3539-3547.
40. Yaghoobian J, Morieux C, Denne AM, Bouizar Z, Urena P, de Vemejoul CM (1998). Pamidronate corrects the down-regulation of the renal parathyroid hormone (PTH)/PTH-related peptide (PTHrP) receptor mRNA in rats bearing Walker tumors. Horm Metab Res 30: 249-255.
41. Yamato H, Nagai Y, Inoue D, Ohnishi Y, Ueyama Y, Ohno H, Matsumoto T, Ogata E, Ikeda K (1995). In vivo evidence for progressive activation of parathyroid hormone-related peptide gene transcription with tumor growth and stimulation of osteoblastic bone formation at an early stage of humoral hypercalcemia of cancer. J Bone Miner Res 10: 36-44.