Bicyclic nucleoside inhibitors of varicella-zoster virus: Synthesis and biological evaluation of 2′,3′-dideoxy-3′-fluoro and 2′-deoxy-xylo derivatives

Nucleosides, Nucleotides and Nucleic Acids

Volumn 22, Issue 5-8, 2003, Pages 935-937

  Carangio, A ^a   McGuigan, C ^a   Andrei, G ^b   Snoeck, R ^b   De Clercq, E ^b   Balzarini, J ^b  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

2' DEOXYXYLONUCLEOSIDE; 2',3' DIDEOXY 3' FLUORONUCLEOSIDE; 5 IODO 2' DEOXYXYLOURIDINE; 5 IODO 2',3' DIDEOXY 3' FLUOROURIDINE; ACICLOVIR; ANTIVIRUS AGENT; DEOXYURIDINE; NUCLEOSIDE DERIVATIVE; PALLADIUM; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; CONFERENCE PAPER; DRUG SYNTHESIS; STRUCTURE ACTIVITY RELATION; VARICELLA ZOSTER VIRUS;

ACYCLOVIR; ANTIVIRAL AGENTS; BICYCLO COMPOUNDS; FLUORIDES; HERPESVIRUS 3, HUMAN; INDICATORS AND REAGENTS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; NUCLEOSIDES; STRUCTURE-ACTIVITY RELATIONSHIP; XYLOSE;

HUMAN HERPESVIRUS 3;

EID: 0141648290     PISSN: 15257770     EISSN: None     Source Type: Journal    
DOI: 10.1081/NCN-120022689     Document Type: Conference Paper

References (4)

1. McGuigan, C.; Yarnold, C.J.; Jones, G.; Velázquez, S.; Barucki, H.; Brancale, A.; Andrei, G.; Snoeck, R.; De Clercq, E.; Balzarini, J. J. Med. Chem. 1999, 42, 4479-4484.
2. McGuigan, C.; Barucki, H.; Blewett; Carangio, A.; Erichsen, J.T.S.; Andrei, G.; Snoeck, R.; De Clercq, E.; Balzarini, J. J. Med. Chem. 2000, 43, 4993-4997.
3. McGuigan, C.; Pathirana, R.N.; Andrei, G.; Snoeck, R.; De Clercq, E.; Balzarini, J. XV International Roundtable on Nucleosides, Nucleotides & Nucleic acids, 2002; 105 pp.
4. Janta-Lipinski, M.; Costisella, B.; Ochs, H.; Hübscher; Hafkemeyer, P.; Matthes, E. J. Med. Chem. 1998, 41, 2040-2046.