First examples of improved catalytic asymmetric C-C bond formation using the monodentate ligand combination approach

Organic Letters

Volumn 5, Issue 17, 2003, Pages 3111-3113

  Duursma, Ate ^a   Hoen, Rob ^a   Schuppan, Julia ^a   Hulst, Ron ^a   Minnaard, Adriaan J ^a   Feringa, Ben L ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON; LIGAND; RHODIUM;

ARTICLE; CATALYSIS; CATALYST; CHEMICAL BOND; CHIRALITY; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE;

EID: 0141631827     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol035106o     Document Type: Article

References (30)

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24. It should be noted that the use of equal amounts of Lx and Ly does not necessarily have to result in a statistical mixture of the homo- and hetero-complex.
25. The use of the small achiral ligand triphenyl phosphite in homo- and hetero-combinations gives almost complete conversions to racemic products, but the fact that this ligand is stable under these reaction conditions is remarkable.
26. For a racemic example, see: Itooka, R.; Iguchi, Y.; Miyaura, N. Chem. Lett. 2001, 722-723.
27. Paras, N. A.; MacMillan, D. W. C. J. Am. Chem. Soc. 2002, 124, 7894-7895.
28. Doublet due to Rh-P coupling.
29. See Supporting Information for details.
30. Imbalance in homo-complex ratios is due to errors in weighing.