Optimization of triple-helix-directed DNA cleavage by benzoquinoquinoxaline - Ethylene-diaminetetraacetic acid conjugates

ChemBioChem

Volumn 4, Issue 9, 2003, Pages 856-862

  Zain, Rula ^a   Polverari, David ^b   Nguyen, Chi Hung ^c   Blouquit, Yves ^c   Bisagni, Emile ^c   Garestier, Thérèse ^b   Grierson, David S ^c   Sun, Jian Sheng ^b  

^a STOCKHOLM UNIVERSITY   (Sweden)

^b MUSÉUM NATIONAL D'HISTOIRE NATURELLE   (France)

^c INSTITUT CURIE   (France)

Author keywords

DNA cleavage; DNA intercalating compounds; Molecular modelling; Oligonucleotides; Triple helix

Indexed keywords

6 (3,3' DIAMINO N METHYLDIPROPYLAMINO)BENZOQUINOQUINOXALINE; 6 [BIS(2 AMINOETHYL)AMINO]BENZOQUINOQUINOXALINE; BENZOQUINOQUINOXALINE; DOUBLE STRANDED DNA; EDETIC ACID; ENDONUCLEASE; FERROUS ION; INTERCALATING AGENT; PLASMID DNA; QUINOXALINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CONJUGATE; COVALENT BOND; DNA BINDING; DNA CLEAVAGE; DNA DENATURATION; MOLECULAR MODEL; PRIORITY JOURNAL; SYNTHESIS; THERMOSTABILITY; TRIPLE HELIX;

DNA; EDETIC ACID; INTERCALATING AGENTS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; NUCLEIC ACID CONFORMATION; PLASMIDS; QUINOXALINES; THERMODYNAMICS;

EID: 0141572117     PISSN: 14394227     EISSN: None     Source Type: Journal    
DOI: 10.1002/cbic.200300621     Document Type: Article

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