Effect of quercetin on hypoxic injury in freshly isolated rat proximal tubules

Journal of Laboratory and Clinical Medicine

Volumn 142, Issue 2, 2003, Pages 106-112

  Pietruck, Frank ^b   Kuhlmann, Martin K ^b   Lange, Bettina ^b   Feldkamp, Thorsten ^b   Herget Rosenthal, Stefan ^b   Rauen, Ursula ^b   Burkhardt, Gunther ^b   Kohler, Hans ^b   Philipp, Thomas ^b   Kribben, Andreas ^a  

^a UNIVERSITY HOSPITAL ESSEN   (Germany)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; ANTIOXIDANT; BIOFLAVONOID; LACTATE DEHYDROGENASE; OXYGEN RADICAL; POTASSIUM ION; QUERCETIN; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ACUTE KIDNEY FAILURE; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ENZYME RELEASE; HYPOXIA; KIDNEY INJURY; KIDNEY PROXIMAL TUBULE; LIPID PEROXIDATION; MALE; NONHUMAN; POTASSIUM CELL LEVEL; RAT;

EID: 0141519191     PISSN: 00222143     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2143(03)00065-9     Document Type: Article

References (38)

1. Brady HR, Singer GG. Acute renal failure. Lancet 1995;346:1533-40.
2. Thadhani R, Pascual M, Bonventre JV. Acute renal failure. N Engl J Med 1996;334:1448-60.
3. Kribben A, Edelstein CL, Schrier RW. Pathophysiology of acute renal failure. J Nephrol 1999;12(suppl 2):S142-51.
4. Mehta RL, McDonald B, Gabbai FB, Pahl M, Pascual MT, Farkas A, et al. A randomized clinical trial of continuous versus intermittent dialysis for acute renal failure. Kidney Int 2001;60:1154-63.
5. Liano F, Pascual J. Epidemiology of acute renal failure: a prospective, multicenter, community-based study. Madrid Acute Renal Failure Study Group. Kidney Int 1996;50:811-8.
6. Paller MS, Hoidal JR, Ferris TF. Oxygen free radicals in ischemic acute renal failure in the rat. J Clin Invest 1984;74:1156-64.
7. Andreoli SP, McAteer JA. Reactive oxygen molecule-mediated injury in endothelial and renal tubular epithelial cells in vitro. Kidney Int 1990;38:785-94.
8. - in posthypoxic injury of renal epithelial cells. Am J Physiol 1992;263:F251-5.
9. Ichikawa I, Kiyama S, Yoshioka T. Renal antioxidant enzymes: their regulation and function. Kidney Int 1994;45:1-9.
10. 2-induced renal epithelial (LLC-PK1) cell injury. Am J Physiol 1995;268:F30-8.
11. Bors W, Heller W, Michel C, Saran M. Flavonoids as antioxidants: determination of radical-scavenging efficiencies. Methods Enzymol 1990;186:343-55.
12. Rice-Evans CA, Miller NJ, Paganga G. Structure-antioxidant activity relationships of flavonoids and phenolic acids. Free Radic Biol Med 1996;20:933-56.
13. Kuhlmann MK, Horsch E, Burkhardt G, Wagner M, Köhler H. Reduction of cisplastin toxicity in cultured renal tubular cells by the bioflavonoid quercetin. Arch Toxicol 1998;72:536-40.
14. Afanas'ev IB, Dorozhko AI, Brodskii AV, Kostyuk VA, Potapovitch AI. Chelating and free radical scavenging mechanisms of inhibitory action of rutin and quercetin in lipid peroxidation. Biochem Pharmacol 1989;38:1763-9.
15. Shoskes DA. Effect of bioflavonoids quercetin and curcumin on ischemic renal injury: a new class of renoprotective agents. Transplantation 1998;66:147-52.
16. Rangan GK, Wang Y, Tay YC, Harris DC. Inhibition of NFkappaB activation with antioxidants is correlated with reduced cytokine transcription in PTC. Am J Physiol 1999;277:F779-89.
17. Yokoo T, Kitamura M. Unexpected protection of glomerular mesangial cells from oxidant- triggered apoptosis by bioflavonoid quercetin. Am J Physiol 1997;273:F206-12.
18. Ishikawa Y, Kitamura M. Bioflavonoid quercetin inhibits mitosis and apoptosis of glomerular cells in vitro and in vivo. Biochem Biophys Res Commun 2000;279:629-34.
19. Kribben A, Wieder ED, Wetzels JFM, Yu L, Gengaro PE, Burke TJ, et al. Evidence for role of cytosolic free calcium in hypoxia-induced proximal tubule injury. J Clin Invest 1994;93:1922-9.
20. Kribben A, Feldkamp T, Hörbelt M, Lange B, Pietruck F, Herget-Rosenthal S, et al. ATP protects, by way of receptor-mediated mechanisms, against hypoxia-induced injury in renal proximal tubules. J Lab Clin Med 2003;141:67-73.
21. Lowry OH, Rosenbrough NJ, Farr AL, Randall AJ. Protein measurement with the folin phenol reagent. J Biol Chem 1951;193:265-75.
22. Wetzels JF, Yu L, Wang X, Kribben A, Burke TJ, Schrier RW. Calcium modulation and cell injury in isolated rat proximal tubules. J Pharmacol Exp Ther 1993;267:176-80.
23. Aust SD. Lipid peroxidation. In: Greenwald RA, ed. CRC Handbook of Methods for Oxygen Radical Research. Boca Raton, Fla: CRC, 1985:203-7.
24. Bradford MM. A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976;72:248-54.
25. 2 formation. FASEB J 2000;14:1953-64.
26. Chen J, Liu X, Mandel LJ, Schnellmann RG. Progressive disruption of the plasma membrane during renal proximal tubule cellular injury. Toxicol Appl Pharmacol 2001;171:1-11.
27. Kourie JI. Interaction of reactive oxygen species with ion transport mechanisms. Am J Physiol 1998;275:C1-24.
28. +-ATPase from its surface membrane actin cytoskeletal complex during cellular ATP depletion. J Clin Invest 1991;88:462-9.
29. +-ATPase activity induced by free radicals and by ischemia of kidney. Am J Physiol 1988;254:C330-7.
30. +-ATPase: aspects of the structure-activity relationship and action mechanism. Life Sci 1989;45:1111-7.
31. +-ATPase by flavonoids and their inotropic effect. Investigation of the structure-activity relationship. Membr Cell Biol 1998;12:27-40.
32. Paller MS, Neumann TV. Reactive oxygen species and rat renal epithelial cells during hypoxia and reoxygenation. Kidney Int 1991;40:1041-9.
33. Gonzalez-Flecha B, Boveris A. Mitochondrial sites of hydrogen peroxide production in reperfused rat kidney cortex. Biochim Biophys Acta 1995;1243:361-6.
34. McCord JM. Oxygen-derived free radicals in postischemic tissue injury. N Engl J Med 1985;312:159-63.
35. Granger DN. Role of xanthine oxidase and granulocytes in ischemia-reperfusion injury. Am J Physiol 1988;255:H1269-75.
36. Eschwege P, Paradis V, Conti M, Holstege A, Richet F, Deteve J, et al. In situ detection of lipid peroxidation by-products as markers of renal ischemia injuries in rat kidneys. J Urol 1999;162:553-7.
37. Santos AC, Uyemura SA, Lopes JL, Bazon JN, Mingatto FE, Curti C. Effect of naturally occurring flavonoids on lipid peroxidation and membrane permeability transition in mitochondria. Free Radic Biol Med 1998;24:1455-61.
38. Lieberthal W, Nigam SK. Acute renal failure. II. Experimental models of acute renal failure: imperfect but indispensable. Am J Physiol Renal Physiol 2000;278:F1-12.