Bioluminescence Monitoring of Photodynamic Therapy Response of Rat Gliosarcoma In Vitro and In Vivo

Proceedings of SPIE - The International Society for Optical Engineering

Volumn 4952, Issue , 2003, Pages 76-81

  Moriyama, E H ^a   Bisland, S K ^a   Lin, A ^a   Bogaards, A ^a   Lilge, L ^a   Wilson, B C ^a,b  

^a UNIVERSITY HEALTH NETWORK   (Canada)

^b PRINCESS MARGARET HOSPITAL   (Canada)

Author keywords

9L gliosarcoma; Bioluminescence; In vivo imaging; Luciferase; PhotodynamicTherapy

Indexed keywords

BIOLUMINESCENCE; BRAIN; GENE TRANSFER; LIGHT; NONINVASIVE MEDICAL PROCEDURES; OXYGEN; PHOTOSENSITIZERS; TUMORS;

BIOLUMINESCENCE MONITORING;

PHOTODYNAMIC THERAPY;

EID: 0141494275     PISSN: 0277786X     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1117/12.488634     Document Type: Conference Paper

References (16)

1. Henderson BW, Dougherty TJ. How does Photodynamic Therapy Work? Photochem Photobiol 1992 55: 777-779.
2. Moan J, Berg K. Photochemotherapy of cancer: experimental research. Photochem Photobiol 1992; 55:931-48
3. Lilge L, Portnoy M, Wilson BC. Apoptosis induced in vivo by photodynamic therapy in normal brain and intracranial tumour tissue. Br J Cancer 2000 83:1110-7.
4. He XY, Sikes RA, Thomsen S, Chung LW, Jacques SL. Photodynamic therapy with Photofrin II induces programmed cell death in carcinoma cell lines. Photochem Photobiol 1994 59:468-73.
5. Krammer B. Vascular effects of photodynamic therapy. Anticancer Res 2001 21:4271-4177.
6. Edinger M, Cao Y, Hornig YS, Jenkins DE, Verneris MR, Bachmann MH, Negrin RS, Contag CH. Advancing animal models of neoplasia through in vivo bioluminescence imaging. Eur J Cancer 2002 38:2128-36.
7. Weissleder R. Scaling down imaging: molecular mapping of cancer in mice. Nat Rev Cancer 2002 2:11-8.
8. Rice BW, Cable, MD, Nelson, MB, In vivo imaging of light-emitting probes. J Biomed Opt 2001 6: 432-440.
9. Eames B, Benaron DA, Steverson DK, Contag CH, Construction and characterization of a red-emitting luciferase. In Biomedical Imaging: Reporters, Dyes and Instrumentation, ed DJ Bornhop, CH Contag, EM Servick-Muraca, pp. 36-39. San Jose, CA: Int. Soc. Opt. Eng.
10. Hastings JW. Chemistries and colors of bioluminescent reactions: a review. Gene 1996 173:5-11.
11. Omiya Y, Hirano T, Ohashi M. The structural origin of the color differences in the bioluminescence of firefly luciferase. FEES Lett 1996, 384: 83-86.
12. Muller PJ, Wilson BC. Photodynamic therapy of malignant primary brain tumours: clinical effects, post-operative ICP, and light penetration of the brain. Photochem Photobiol 1987 46:929-35
13. Ji Y, Walstad D, Brown JT, Powers SK. Improved survival from intracavitary photodynamic therapy of rat glioma. Photochem Photobiol 1992 56:385-90.
14. Rehemtulla A, Stegman LD, Cardozo SJ, Gupta S, Hall DE, Contag CH, Ross BD. Rapid and quantitative assessment of cancer treatment response using in vivo bioluminescence imaging. Neoplasia 2000 2:491-5.
15. Bogaards A, Varma A, Moriyama EH, Lin A, Gilles A, Bisland S, Lilge L, Bilbao GM, Muler, PJ, Wilson BC. Fluorescence-guided resection of intyracranial VX2 tumor in a preclinical model using 5-aminolevulinic acid (ALA): Preliminary results. Proc. SPIE, vol 4952, in press.
16. Wilson BC, Bisland S, Bogaards A, Lin, Moriyama EH. Zhang K, Lilge L. Metronomic photodynamic therapy (mPDT): Concepts and technical feasibility in brain tumor. Proc. SPIE, vol 4952, in press.