메뉴 건너뛰기




Volumn 129, Issue 9, 2003, Pages 511-520

Dendritic cell-based tumor vaccine for cervical cancer I: In vitro stimulation with recombinant protein-pulsed dendritic cells induces specific T cells to HPV16 E7 or HPV18 E7

Author keywords

Cytotoxic T cell; Immunotherapy; T cell response; Tumor infiltrating lymphocytes; Uterine cancer

Indexed keywords

CANCER VACCINE; CD4 ANTIGEN; CD8 ANTIGEN; EPITOPE; GAMMA INTERFERON; HLA A ANTIGEN; ONCOPROTEIN; RECOMBINANT ANTIGEN; TUMOR VACCINE; UNCLASSIFIED DRUG; VIRUS PROTEIN; WART VIRUS E7 ANTIGEN;

EID: 0141484489     PISSN: 01715216     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00432-003-0462-6     Document Type: Article
Times cited : (41)

References (53)
  • 2
    • 0031194898 scopus 로고    scopus 로고
    • A general purification protocol for E7 proteins from "high- and low-risk" human papillomavirus types expressed in the yeast Schizosaccharomyces pombe
    • Braspenning J, Manetti R, Zumbach K, Meschede W, Gissmann L, Tommasino M (1997) A general purification protocol for E7 proteins from "high- and low-risk" human papillomavirus types expressed in the yeast Schizosaccharomyces pombe. Protein Expr Purif 10:192-201
    • (1997) Protein Expr Purif , vol.10 , pp. 192-201
    • Braspenning, J.1    Manetti, R.2    Zumbach, K.3    Meschede, W.4    Gissmann, L.5    Tommasino, M.6
  • 3
    • 0026451456 scopus 로고
    • Epidemiology of cervical cancer-overview
    • Brinton LA (1992) Epidemiology of cervical cancer-overview. IARC Sci Publ 119:3-23
    • (1992) IARC Sci Publ , vol.119 , pp. 3-23
    • Brinton, L.A.1
  • 4
    • 0034944974 scopus 로고    scopus 로고
    • Synthetic peptides induce a cytotoxic response against human papillomavirus type-18
    • Castellanos MR, Hayes RL, Maiman MA (2001) Synthetic peptides induce a cytotoxic response against human papillomavirus type-18. Gynecol Oncol 82:77-83
    • (2001) Gynecol Oncol , vol.82 , pp. 77-83
    • Castellanos, M.R.1    Hayes, R.L.2    Maiman, M.A.3
  • 9
    • 0030871774 scopus 로고    scopus 로고
    • Infiltration of cervical cancer tissue with human papillomavirus-specific cytotoxic T-lymphocytes
    • Evans EM, Man S, Evans AS, Borysiewicz LK (1997) Infiltration of cervical cancer tissue with human papillomavirus-specific cytotoxic T-lymphocytes. Cancer Res 57:2943-2950
    • (1997) Cancer Res , vol.57 , pp. 2943-2950
    • Evans, E.M.1    Man, S.2    Evans, A.S.3    Borysiewicz, L.K.4
  • 11
    • 0033724871 scopus 로고    scopus 로고
    • Tumor antigen pulsed dendritic cells enhance the cytolytic activity of tumor infiltrating lymphocytes in human hepatocellular cancer
    • Friedl J, Stift A, Paolini P, Roth E, Steger GG, Mader R, Jakesz R, Gnant MF (2000) Tumor antigen pulsed dendritic cells enhance the cytolytic activity of tumor infiltrating lymphocytes in human hepatocellular cancer. Cancer Biother Radiopharm 15:477-486
    • (2000) Cancer Biother Radiopharm , vol.15 , pp. 477-486
    • Friedl, J.1    Stift, A.2    Paolini, P.3    Roth, E.4    Steger, G.G.5    Mader, R.6    Jakesz, R.7    Gnant, M.F.8
  • 12
    • 0028325368 scopus 로고
    • Risk of genital human papillomavirus infection in women with human immunodeficiency virus-induced immunosuppression
    • Ho GY, Burk RD, Fleming I, Klein RS (1994) Risk of genital human papillomavirus infection in women with human immunodeficiency virus-induced immunosuppression. Int J Cancer 56:788-792
    • (1994) Int J Cancer , vol.56 , pp. 788-792
    • Ho, G.Y.1    Burk, R.D.2    Fleming, I.3    Klein, R.S.4
  • 14
    • 0031057725 scopus 로고    scopus 로고
    • A general primer GP5+/GP6(+)-mediated PCR-enzyme immunoassay method for rapid detection of 14 high-risk and 6 low-risk human papillomavirus genotypes in cervical scrapings
    • Jacobs MV, Snijders PJ, van den Brule AJ, Helmerhorst TJ, Meijer C J, Walboomers JM (1997) A general primer GP5+/GP6(+)-mediated PCR-enzyme immunoassay method for rapid detection of 14 high-risk and 6 low-risk human papillomavirus genotypes in cervical scrapings. J Clin Microbiol 35:791-795
    • (1997) J Clin Microbiol , vol.35 , pp. 791-795
    • Jacobs, M.V.1    Snijders, P.J.2    Van Den Brule, A.J.3    Helmerhorst, T.J.4    Meijer, C.J.5    Walboomers, J.M.6
  • 15
    • 2642631750 scopus 로고    scopus 로고
    • Pro-inflammatory cytokines and prostaglandins induce maturation of potent immunostimulatory dendritic cells under fetal calf serum-free conditions
    • Jonuleit H, Kuhn U, Muller G, Steinbrink K, Paragnik L, Schmitt E, Knop J, Enk AH (1997) Pro-inflammatory cytokines and prostaglandins induce maturation of potent immunostimulatory dendritic cells under fetal calf serum-free conditions. Eur J Immunol 27:3135-3142
    • (1997) Eur J Immunol , vol.27 , pp. 3135-3142
    • Jonuleit, H.1    Kuhn, U.2    Muller, G.3    Steinbrink, K.4    Paragnik, L.5    Schmitt, E.6    Knop, J.7    Enk, A.H.8
  • 16
    • 0037431437 scopus 로고    scopus 로고
    • Identification of a naturally processed HLA-A*0201 HPV18 E7 T cell epitope by tumor cell mediated in vitro vaccination
    • Kather A, Ferrara A, Nonn M, Schinz M, Nieland J, Schneider A, Dürst M, Kaufmann AM (2003) Identification of a naturally processed HLA-A*0201 HPV18 E7 T cell epitope by tumor cell mediated in vitro vaccination. Int J Cancer 104:345-353
    • (2003) Int J Cancer , vol.104 , pp. 345-353
    • Kather, A.1    Ferrara, A.2    Nonn, M.3    Schinz, M.4    Nieland, J.5    Schneider, A.6    Dürst, M.7    Kaufmann, A.M.8
  • 17
    • 0031262740 scopus 로고    scopus 로고
    • Cervical carcinoma cells transfected with the CD80 gene elicit a primary cytotoxic T lymphocyte response specific for HPV 16 E7 antigens
    • Kaufmann AM, Gissmann L, Schreckenberger C, Qiao L (1997) Cervical carcinoma cells transfected with the CD80 gene elicit a primary cytotoxic T lymphocyte response specific for HPV 16 E7 antigens. Cancer Gene Ther4:377-382
    • (1997) Cancer Gene Ther , vol.4 , pp. 377-382
    • Kaufmann, A.M.1    Gissmann, L.2    Schreckenberger, C.3    Qiao, L.4
  • 18
    • 0033677182 scopus 로고    scopus 로고
    • Comparison of cytokines and CD80 for enhancement of immunogenicity of cervical cancer cells
    • Kaufmann AM, Gissmann I, Simms P, Schreckenberger C, Qiao L (2000) Comparison of cytokines and CD80 for enhancement of immunogenicity of cervical cancer cells. Immunobiol 202:339-352
    • (2000) Immunobiol , vol.202 , pp. 339-352
    • Kaufmann, A.M.1    Gissmann, I.2    Simms, P.3    Schreckenberger, C.4    Qiao, L.5
  • 20
    • 0035207017 scopus 로고    scopus 로고
    • Rapid induction of cytotoxic T cell response against cervical cancer cells by human papillomavirus type 16 E6 antigen gene delivery into human dendritic cells by an adeno-associated virus vector
    • Liu Y, Chiriva-Internati M, Grizzi F, Salati E, Roman J J, Lira S, Hermonat PL (2001) Rapid induction of cytotoxic T cell response against cervical cancer cells by human papillomavirus type 16 E6 antigen gene delivery into human dendritic cells by an adeno-associated virus vector. Cancer Gene Ther 8:948-957
    • (2001) Cancer Gene Ther , vol.8 , pp. 948-957
    • Liu, Y.1    Chiriva-Internati, M.2    Grizzi, F.3    Salati, E.4    Roman, J.J.5    Lira, S.6    Hermonat, P.L.7
  • 22
    • 0036983428 scopus 로고    scopus 로고
    • T cell response against human papillomavirus (HPV) 16 E7 in mice: Comparison of Cr-release assay, intracellular IFN-γ production. ELISPOT and tetramer staining
    • Michel N, Öhlschläger P, Osen W, Freyschmidt EJ, Guthörlein H, Kaufmann A, Müller M, Gissmann L (2002) T cell response against human papillomavirus (HPV) 16 E7 in mice: comparison of Cr-release assay, intracellular IFN-γ production, ELISPOT and tetramer staining. Intervirology 45:290-299
    • (2002) Intervirology , vol.45 , pp. 290-299
    • Michel, N.1    Öhlschläger, P.2    Osen, W.3    Freyschmidt, E.J.4    Guthörlein, H.5    Kaufmann, A.6    Müller, M.7    Gissmann, L.8
  • 23
    • 0033048533 scopus 로고    scopus 로고
    • Presentation of renal tumor antigens by human dendritic cells activates tumor-infiltrating lymphocytes against autologous tumor: Implications for live kidney cancer vaccines
    • Mulders P, Tso CL, Gitlitz B, Kaboo R, Hinkel A, Frand S, Kiertscher S, Roth MD, deKernion J, Figlin R, Belldegrun A (1999) Presentation of renal tumor antigens by human dendritic cells activates tumor-infiltrating lymphocytes against autologous tumor: implications for live kidney cancer vaccines. Clin Cancer Res 5:445-454
    • (1999) Clin Cancer Res , vol.5 , pp. 445-454
    • Mulders, P.1    Tso, C.L.2    Gitlitz, B.3    Kaboo, R.4    Hinkel, A.5    Frand, S.6    Kiertscher, S.7    Roth, M.D.8    DeKernion, J.9    Figlin, R.10    Belldegrun, A.11
  • 24
    • 0033813525 scopus 로고    scopus 로고
    • A phase I trial of a human papillomavirus (HPV) peptide vaccine for women with high-grade cervical and vulvar intraepithelial neoplasia who are HPV 16 positive
    • Munderspach L, Wilczynski S, Roman L, Bade L, Felix J, Small LA, Kast MW, Fascio G, Marty V, Weber J (2000) A phase I trial of a human papillomavirus (HPV) peptide vaccine for women with high-grade cervical and vulvar intraepithelial neoplasia who are HPV 16 positive. Clin Canc Res 6:3406-3416
    • (2000) Clin Canc Res , vol.6 , pp. 3406-3416
    • Munderspach, L.1    Wilczynski, S.2    Roman, L.3    Bade, L.4    Felix, J.5    Small, L.A.6    Kast, M.W.7    Fascio, G.8    Marty, V.9    Weber, J.10
  • 25
    • 0033559604 scopus 로고    scopus 로고
    • Induction of specific CD8+ T-lymphocyte responses using a human papillomavirus-16 E6/E7 fusion protein and autologous dendritic cells
    • Murakami M, Gurski KJ, Marincola FM, Ackland J, Steller MA (1999) Induction of specific CD8+ T-lymphocyte responses using a human papillomavirus-16 E6/E7 fusion protein and autologous dendritic cells. Cancer Res 59:1184-1187
    • (1999) Cancer Res , vol.59 , pp. 1184-1187
    • Murakami, M.1    Gurski, K.J.2    Marincola, F.M.3    Ackland, J.4    Steller, M.A.5
  • 27
    • 43949158868 scopus 로고
    • Immunological functions of nonprofessional antigen-presenting cells: New insights from studies of T-cell interaction with keratinocytes
    • Nikoloff B, Turka L (1994) Immunological functions of nonprofessional antigen-presenting cells: new insights from studies of T-cell interaction with keratinocytes. Immunol Today 15:464-469
    • (1994) Immunol Today , vol.15 , pp. 464-469
    • Nikoloff, B.1    Turka, L.2
  • 28
    • 0032945847 scopus 로고    scopus 로고
    • Distribution of 14 high risk HPV types in cervical intraepithelial neoplasia detected by a non-radioactive general primer PCR mediated enzyme immunoassay
    • Nindl I, Lotz B, Kuhne-Heid R, Endisch U, Schneider A (1999) Distribution of 14 high risk HPV types in cervical intraepithelial neoplasia detected by a non-radioactive general primer PCR mediated enzyme immunoassay. J Clin Pathol 52:17-22
    • (1999) J Clin Pathol , vol.52 , pp. 17-22
    • Nindl, I.1    Lotz, B.2    Kuhne-Heid, R.3    Endisch, U.4    Schneider, A.5
  • 29
    • 0028811392 scopus 로고
    • Dendritic cells as carriers for a cytotoxic T-lymphocyte epitope-based peptide vaccine in protection against a human papillomavirus type 16-induced tumor
    • Ossevoort MA, Feltkamp MC, van Veen KJ, Melief CJ, Kast WM (1995) Dendritic cells as carriers for a cytotoxic T-lymphocyte epitope-based peptide vaccine in protection against a human papillomavirus type 16-induced tumor. J Immunother Emphasis Tumor Immunol 18:86-94
    • (1995) J Immunother Emphasis Tumor Immunol , vol.18 , pp. 86-94
    • Ossevoort, M.A.1    Feltkamp, M.C.2    Van Veen, K.J.3    Melief, C.J.4    Kast, W.M.5
  • 31
    • 0029035637 scopus 로고
    • Human CTL epitopes encoded by human papillomavirus type 16 E6 and E7 identified through in vivo and in vitro immunogenicity studies of HLA-A*0201-binding peptides
    • Ressing ME, Sette A, Brandt RMP, Ruppert J, Wentworth PA, Hartman M, Oseroff C, Grey HM, Melief CJM, Kast WM (1995) Human CTL epitopes encoded by human papillomavirus type 16 E6 and E7 identified through in vivo and in vitro immunogenicity studies of HLA-A*0201-binding peptides. J Immunol 154:5934-5943
    • (1995) J Immunol , vol.154 , pp. 5934-5943
    • Ressing, M.E.1    Sette, A.2    Brandt, R.M.P.3    Ruppert, J.4    Wentworth, P.A.5    Hartman, M.6    Oseroff, C.7    Grey, H.M.8    Melief, C.J.M.9    Kast, W.M.10
  • 33
    • 0033203120 scopus 로고    scopus 로고
    • Selective transport of internalized antigens to the cytosol for MHC class I presentation in dendritic cells
    • Rodriguez A, Regnault A, Kleijmeer M, Ricciardi-Castagnoli P, Amigorena S (1999) Selective transport of internalized antigens to the cytosol for MHC class I presentation in dendritic cells. Nat Cell Biol 1:362-368
    • (1999) Nat Cell Biol , vol.1 , pp. 362-368
    • Rodriguez, A.1    Regnault, A.2    Kleijmeer, M.3    Ricciardi-Castagnoli, P.4    Amigorena, S.5
  • 35
    • 0030603987 scopus 로고    scopus 로고
    • Generation of mature dendritic cells from human blood. An improved method with special regard to clinical applicability
    • Romani N, Reider D, Heuer M, Ebner S, Kampgen E, Eibl B, Niederwieser D, Schuler G (1996) Generation of mature dendritic cells from human blood. An improved method with special regard to clinical applicability. J Immunol Methods 196:137-151
    • (1996) J Immunol Methods , vol.196 , pp. 137-151
    • Romani, N.1    Reider, D.2    Heuer, M.3    Ebner, S.4    Kampgen, E.5    Eibl, B.6    Niederwieser, D.7    Schuler, G.8
  • 36
    • 0035288013 scopus 로고    scopus 로고
    • Human T cell responses to HLA-A-restricted high binding affinity peptides of human papillomavirus type 18 proteins E6 and E7
    • Rudolf MP, Man S, Melief CJ, Sette A, Kast WM (2001) Human T cell responses to HLA-A-restricted high binding affinity peptides of human papillomavirus type 18 proteins E6 and E7. Clin Cancer Res 7:788s-795s
    • (2001) Clin Cancer Res , vol.7
    • Rudolf, M.P.1    Man, S.2    Melief, C.J.3    Sette, A.4    Kast, W.M.5
  • 37
    • 0029148878 scopus 로고
    • Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: Downregulation by cytokines and bacterial products
    • Sallusto F, Cella M, Danieli C, Lanzavecchia A (1995) Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products. J Exp Med 182:389-400
    • (1995) J Exp Med , vol.182 , pp. 389-400
    • Sallusto, F.1    Cella, M.2    Danieli, C.3    Lanzavecchia, A.4
  • 38
    • 0033056681 scopus 로고    scopus 로고
    • Induction of human papillomavirus-specific CD4(+) and CD8(+) lymphocytes by E7-pulsed autologous dendritic cells in patients with human papillomavirus type 16- and 18-positive cervical cancer
    • Santin AD, Hermonat PL, Ravaggi A, Chiriva-Internati M, Zhan D, Pecorelli S, Parham GP, Cannon MJ (1999) Induction of human papillomavirus-specific CD4(+) and CD8(+) lymphocytes by E7-pulsed autologous dendritic cells in patients with human papillomavirus type 16- and 18-positive cervical cancer. J Virol 73:5402-5410
    • (1999) J Virol , vol.73 , pp. 5402-5410
    • Santin, A.D.1    Hermonat, P.L.2    Ravaggi, A.3    Chiriva-Internati, M.4    Zhan, D.5    Pecorelli, S.6    Parham, G.P.7    Cannon, M.J.8
  • 39
    • 0035290235 scopus 로고    scopus 로고
    • Expression of CD56 by human papillomavirus E7-specific CDS+ cytotoxic T tymphocytes correlates with increased intracellular perforin expression and enhanced cytotoxicity against HLA-A2-matched cervical tumor cells
    • Santin AD, Hermonat PL, Ravaggi A, Bellone S, Roman JJ, Jayaprabhu S, Pecorelli S, Parham GP, Cannon MJ (2001) Expression of CD56 by human papillomavirus E7-specific CDS+ cytotoxic T tymphocytes correlates with increased intracellular perforin expression and enhanced cytotoxicity against HLA-A2-matched cervical tumor cells. Clin Cancer Res 7:804s-810s
    • (2001) Clin Cancer Res , vol.7
    • Santin, A.D.1    Hermonat, P.L.2    Ravaggi, A.3    Bellone, S.4    Roman, J.J.5    Jayaprabhu, S.6    Pecorelli, S.7    Parham, G.P.8    Cannon, M.J.9
  • 40
    • 0030840111 scopus 로고    scopus 로고
    • Dendritic cells as adjuvants for immune-mediated resistance to tumors
    • Schuler G, Steinman RM (1997) Dendritic cells as adjuvants for immune-mediated resistance to tumors. J Exp Med 186:1183-1187
    • (1997) J Exp Med , vol.186 , pp. 1183-1187
    • Schuler, G.1    Steinman, R.M.2
  • 41
    • 0025735629 scopus 로고
    • The dendritic cell system and its role in immunogenicity
    • Steinman RM (1991) The dendritic cell system and its role in immunogenicity. Annu Rev Immunol 9:271-296
    • (1991) Annu Rev Immunol , vol.9 , pp. 271-296
    • Steinman, R.M.1
  • 43
    • 0027345633 scopus 로고
    • Immunosuppressive factors in human cancer
    • Sulitzeanu D (1993) Immunosuppressive factors in human cancer. Adv Cancer Res 60:247-267
    • (1993) Adv Cancer Res , vol.60 , pp. 247-267
    • Sulitzeanu, D.1
  • 45
    • 1842370254 scopus 로고    scopus 로고
    • Genetically modified bone marrow-derived dendritic cells expressing tumor-associated viral or "self" antigens induce antitumor immunity in vivo
    • Tuting T, DeLeo AB, Lotze MT, Storkus WJ (1997) Genetically modified bone marrow-derived dendritic cells expressing tumor-associated viral or "self" antigens induce antitumor immunity in vivo. Eur J Immunol 27:2702-2707
    • (1997) Eur J Immunol , vol.27 , pp. 2702-2707
    • Tuting, T.1    DeLeo, A.B.2    Lotze, M.T.3    Storkus, W.J.4
  • 46
    • 0023809597 scopus 로고
    • Correlation of modified human papilloma virus early gene expression with altered growth properties in C4-1 cervical carcinoma cells
    • von Knebel-Doeberitz M, Oltersdorf T, Schwarz E, Gissmann L (1988) Correlation of modified human papilloma virus early gene expression with altered growth properties in C4-1 cervical carcinoma cells. Cancer Res 48:3780-3786
    • (1988) Cancer Res , vol.48 , pp. 3780-3786
    • Von Knebel-Doeberitz, M.1    Oltersdorf, T.2    Schwarz, E.3    Gissmann, L.4
  • 47
    • 0026691230 scopus 로고
    • Inhibition of tumorigenicity of cervical cancer cells in nude mice by HPV E6-E7 anti-sense RNA
    • von Knebel-Doeberitz M, Rittmuller C, zur Hausen H, Durst M (1992) Inhibition of tumorigenicity of cervical cancer cells in nude mice by HPV E6-E7 anti-sense RNA. Int J Cancer 51:831-834
    • (1992) Int J Cancer , vol.51 , pp. 831-834
    • Von Knebel-Doeberitz, M.1    Rittmuller, C.2    Zur Hausen, H.3    Durst, M.4
  • 50
    • 0036317624 scopus 로고    scopus 로고
    • Analysis of CD4(+) T-cell responses to human papillomavirus (HPV) type 11 L1 in healthy adults reveals a high degree of responsiveness and cross-reactivity with other HPV types
    • Williams OM, Hart KW, Wang EC, Gelder CM (2002) Analysis of CD4(+) T-cell responses to human papillomavirus (HPV) type 11 L1 in healthy adults reveals a high degree of responsiveness and cross-reactivity with other HPV types. J Virol 76:7418-7429
    • (2002) J Virol , vol.76 , pp. 7418-7429
    • Williams, O.M.1    Hart, K.W.2    Wang, E.C.3    Gelder, C.M.4
  • 51
    • 0037142181 scopus 로고    scopus 로고
    • Identification of a new proliferation-associated protein NET-1/C4.8 characteristic for a subset of high-grade cervical intraepithelial neoplasia and cervical carcinomas
    • Wollscheid V, Kuhne-Heid R, Stein I, Jansen L, Kollner S, Schneider A, Durst M (2002) Identification of a new proliferation-associated protein NET-1/C4.8 characteristic for a subset of high-grade cervical intraepithelial neoplasia and cervical carcinomas. Int J Cancer 99:771-775
    • (2002) Int J Cancer , vol.99 , pp. 771-775
    • Wollscheid, V.1    Kuhne-Heid, R.2    Stein, I.3    Jansen, L.4    Kollner, S.5    Schneider, A.6    Durst, M.7
  • 53
    • 0025886714 scopus 로고
    • Human papillomaviruses in the pathogenesis of anogenital cancer
    • zur Hausen H (1991) Human papillomaviruses in the pathogenesis of anogenital cancer. Virology 184:9-13
    • (1991) Virology , vol.184 , pp. 9-13
    • Zur Hausen, H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.