Synthesis of novel heterocyclic compounds: Routes to pyrazolyl 1,2,3-triazoles and their biological activity evaluation

Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry

Volumn 42, Issue 8, 2003, Pages 1950-1957

  Kumar, Ajay ^a,b   Husain, Mofazzal ^a,c   Prasad, Ashok K ^a   Singh, Ishwar ^a   Vats, Archana ^a   Sharma, Nawal K ^a,b   Sharma, Sunil K ^a   Gupta, Rajinder K ^c   Olsend, Carl E ^d   Bracke, Marc E ^e   Gross, Richard A ^c   Parmar, Virinder S ^a,b  

^a UNIVERSITY OF DELHI   (India)

^b POLYTECHNIC UNIVERSITY   (United States)

^c GURU GOBIND SINGH INDRAPRASTHA UNIVERSITY   (India)

^d UNIVERSITY OF COPENHAGEN   (Denmark)

^e GHENT UNIVERSITY HOSPITAL   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

3 CYANO 4 METHYLTHIO 2H PYRAN 2 ONE; 3 CYANOMETHYLPYRAZOLE; 5 AMINO 1,2,3 TRIAZOLE; ANTIMYCOBACTERIAL AGENT; ANTINEOPLASTIC AGENT; BASE; CARBENE; HETEROCYCLIC COMPOUND; HYDRAZINE; PYRAN DERIVATIVE; PYRAZOLYL 1,2,3 TRIAZOLE; TRIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CATALYSIS; CATALYST; CELL STRAIN MCF 7; DRUG EFFICACY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; POLYMERIZATION; REACTION ANALYSIS; SOLID TUMOR; STRUCTURE ANALYSIS;

EID: 0141481261     PISSN: 03764699     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. For example, there are 2292 pyrazoles in the MDL Drug Report (MDDR-3D, 99.2) representing 2.5% of entries in Comprehensive Medicinal Chemistry (CMC-3D, 99.1). Both data-bases are from MDL Information System.
2. Behr L C, Fusco R & Jarboe C H, The Chemistry of Heterocyclic Compounds, Pyrazoles, Pyrazolines, Pyrazolidines, Imidazoles and Condensed Rings, Edited by A. Weissberger; (Interscience Publishers, New York), 1967, p1.
3. Wiley R H & Wiley P, Pyrazolones, Pyrazolidines and Derivatives (John Wiley and Sons, New York), 1964, p102.
4. Rainer G, Krueger U & Klemm K, Arzneim Forsch. 31, 1981, 649; Chem Abstr, 95, 1981, 90723.
5. Rainer G, Krueger U & Klemm K, Arzneim Forsch. 31, 1981, 649; Chem Abstr, 95, 1981, 90723.
6. Rosiere C E & Grossman M I, Science 113, 1951, 651.
7. Bailey D M, Hansen P E, Hlavac A G, Baizman E R, Pearl J, Defilice A F & Feigenoson M E, J Med Chem, 28, 1985, 256.
8. Seki K, Watanable T T & Suga T, Chem Pharm Bull, 36, 1988, 1117.
9. Mahajan R N, Havaldar F H & Fernandes P S, J Indian Chem Soc, 68, 1991, 245.
10. Lepage F & Hubolt B, Eur Pat Appl EP, 459, 887; Chem Abstr, 116, 1992, 128914.
11. Chauhan P M S, Singh S, Chatterjee R K, Indian J Chem, 32B, 1993, 858.
12. Kurowaski M, Dunky A & Geddawi M, Eur J Clin Pharmacol, 307, 1987, 31.
13. Leenen F H, Smith D L & Unger W P, Br J Clin Pharmacol, 26, 1988, 481.
14. Dutra G A, Hamper B C, Mischke D A, Moedritzer K & Rogers M D, PCT Int Appl, WO 8206, 962; Chem Abstr, 117, 1992, 69859.
15. Suzuki H, Hanaue M & Nishikubo M, Jpn Kokai Tokkyo Koho JP, 03, 236, 368; Chem Abstr, 116, 1993, 106285.
16. Natsume B, Kyomura N, Kikutake K & Fukush, T, Eur Pat Appl EP, 462, 573; Chem Abstr, 116, 1992, 128.
17. Londershausen M, Pestic Sci, 48, 1996, 269.
18. Naito Y, Akahoshi F, Takeda S, Okada T, Kajii M, Nishimura H, Sugiura C, Fukaya M & Kagitani Y, J Med Chem, 39, 1996, 3019.
19. Parmar V S, Jain S C, Jha A, Kumar N, Kumar A, Vats A, Jha H N, Mukherjec S, Singh S K, Jennings, K R, Summerfield S G, Errington W & Olsen C E, Indian J Chem, 36B, 1997, 872.
20. Parmar V S, Sharma N K, Husain M, Watterson A C, Kumar J, Samuelson L A, Cholli A L, Prasad A K, Kumar A, Malhotra S, Kumar N, Jha A, Singh A, Singh I, Himanshu, Vats A, Shakil N A, Trikha S, Mukherjee S, Sharma S K, Singh S K, Kumar A, Jha H N, Olsen C E, Stove C P, Bracke M E & Mareel M M, Bioorg Med Chem, 11, 2003, in print.
21. Parmar V S, Vardhan A, Sharma S K, Sharma N K & Bisht K S, Indian J Chem, 33B, 1994, 17.
22. Parmar V S, Gupta S, Sinha R & Sharma S K, Indian J Chem, 32B, 1993, 244.
23. Parmar V S, Kumar A, Prasad A K, Singh S K, Kumar N, Mukherjec S, Raj H G, Goel S, Errington W & Puar M S, Bioorg Med Chem, 7, 1999, 1425.
24. Kumar A, Malhotra S, Vats A, Himanshu, Singh S K, Sharma S K, Prasad A K, Errington W, Olsen C E, Jain S C & Parmar, VS, Indian J Chem, 41B, 2002, 360.
25. Dimorth O, Ann 1909, 364, 183.
26. Lieber E, Chao T S & Rao C N R, J Org Chem, 22, 1957, 654.
27. Lieber E, Chao T S & Rao C N R, J Org Chem, 22, 1957, 238.
28. Parmar V S, Bracke M E, Philippe J, Wengel J, Jain S C, Olsen C E, Bisht K S, Sharma N K, Courtens A, Sharma S K, Vennekens K, Marck V V, Singh S K, Kumar N, Kumar A, Malhotra S, Kumar R, Rajwanshi V K, Jain R & Mareel M M, Bioorg Med Chem, 5, 1997, 1609.
29. Dye C, Scheele S, Dolin P, Pathania V & Raviglione M C, J Am Med Assoc, 282, 1999, 677.
30. The WHO/IUATLD Global Project on Anti-Tuberculosis Drug Resistance Surveillance 1997-2000.
31. Souter A, McLean K J, Suith W E & Munro A W, J Chem Techno Biotechnol, 75, 2000, 933.
32. Tominaga Y, Ushirogochi A, Matsuda Y & Kobayashi, G Chem Pharm Bull, 32, 1984, 3384.
33. Ram V J, Haque N, Singh S K, Hussaini F A & Shoeb A, Indian J Chem, 32B, 1993, 924.
34. Bracke M E & Mareel M M, In Cell & Tissue Culture: Laboratory Procedures, Edited by A Doyle, J B Griffiths, D G Newell (John Wiley & Sons, Chichester), 1994, Vol 5A:4, pp 1-16.
35. Mareel M M, Kint J & Meyvisch C, Virchows Arch B: Cell Pathol 30, 1979, 95.
36. Coopman P J, Bracke M E, Lissitzky J C, De Bruyne, G K, Van Roy F M, Foidart J M & Mareel M M, J Cell Sci, 98, 1991, 395.
37. Bracke M E, Van Larebeke N A, Vyncke B M & Mareel M M, Br J Cancer, 63, 1991, 867.
38. Correc P, Fondaneche M C, Bracke M E & Burtin P, Int J Cancer, 46, 1990, 745.
39. Plessers L, Bosmans E, Cox A & Raus J, Anticancer Res, 6, 1986, 885.
40. Collins L & Franzblau S G, Antimicrob Agents Chemother, 41, 1997, 1004.