"Acute vegatative state" and "persistent vegatative state": Clinical, biochemical, electrophysiological, and brain imaging data;"Acute vegetative state" und "persistent vegetative state": Klinische, biochemische, elektrophysiologische und bildgebende befunde

Intensivmedizin und Notfallmedizin

Volumn 40, Issue 6, 2003, Pages 462-474

  Haupt, W F ^a   Firsching, R ^b   Hansen, H C ^c   Henze, T H ^d   Horn, M ^e   Janzen, R W C ^f   Neuen Jakob, E ^g   Prange, H W ^h   Zschocke, S T ⁱ   Rudolf, J ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

^b Neurochirurgische Universitatsklinik   (Germany)

^c Neurologisch Psychiatrische Klinik   (Germany)

^d Klinik am Regenbogen   (Germany)

^e UNIVERSITY HOSPITAL REGENSBURG   (Germany)

^f KRANKENHAUS NORDWEST   (Germany)

^g Department of Orthopedic Surgery   (Germany)

^h UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

ⁱ UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

Acute vegetative state; Biochemical markers; Diagnosis; Neurophysiology; Persistent vegetative state; Prognosis

Indexed keywords

BIOCHEMICAL MARKER; CARBON 11; FLUMAZENIL; FLUMAZENIL C 11; FLUORODEOXYGLUCOSE F 18; RADIOISOTOPE; UNCLASSIFIED DRUG;

ACUTE VEGETATIVE STATE; AUTONOMIC DYSFUNCTION; AUTONOMIC NERVOUS SYSTEM; BRAIN FUNCTION; BRAIN SCINTISCANNING; CLINICAL EXAMINATION; CLINICAL FEATURE; CONSCIOUSNESS; DIAGNOSTIC IMAGING; ELECTROENCEPHALOGRAM; ELECTROPHYSIOLOGY; ENDOCRINOLOGY; EVOKED SOMATOSENSORY RESPONSE; GERMANY; HUMAN; IMAGE ANALYSIS; MOTOR ACTIVITY; NEUROPATHOLOGY; NEUROPHYSIOLOGY; NEURORADIOLOGY; PARAMETER; PERSISTENT VEGETATIVE STATE; POSITRON EMISSION TOMOGRAPHY; PROGNOSIS; PUPIL REFLEX; REVIEW;

EID: 0141460519     PISSN: 01753851     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00390-003-0352-9     Document Type: Review

References (56)

1. Adams JH, Graham DI, Jennett B (2000) The neuropathology of the vegetative state after an acute brain insult, Brain 123:1327-1338
2. American Congress of Rehabilitative Medicine (1995) Recommendations for use of uniform nomenclature pertinent to patients with severe alterations in consciousness. Arch Phys Med Rehabil 76:205-209
3. ANA Committee on Ethical Affairs (1993) Persistent Vegetative State: Report of the American Neurological Association Committee on Ethical Affairs. Ann Neurol 33:386-390
4. Andrews K, Murphy L, Littlewood C (1996) Misdiagnosis of the vegetative state: retrospective study in a rehabilitation unit. Br Med J 313:13-16
5. Andrews K (1999) The vegetative state - clinical diagnosis. Postgrad Med J 75:321-324
6. Bassetti C, Mathis J, Hess CW (1994) Multimodal electrophysiological studies including motor evoked potentials in patients with locked-in syndrome: report of six patients. J Neurol Neurosurg Psychiat 57:1403-1406
7. Beil C, Rudolf J, Neveling M, Pawlik G, Haupt WF, Szelies B, Hojer C, Heiss WD (1989) Correlation of PET measurements and electrodiagnostic findings in vegetative states. J Cereb Blood Flow Metab 9 (Suppl 1):S 728
8. Beil C, Kessler J, Grond M, Neveling M, Pietrzyk U, Pawlik G, Heiss WD (1991) Long-term follow-up of PET, MRI and neuropsychological findings in two patients with postanoxic amnesic syndrome. J Cereb Blood Flow Metab 11 (Suppl 2):S 233
9. Biniek R, Ferbert A, Rimpel J, Paepke U, Berns T, Schuchardt V, Heitmann R (1989) The complete apallic syndrome. Int Care Med 15:212-215
10. Childs NL, Mercer WE, Childs HW (1993) Accuracy of diagnosis of persistent vegetative state. Neurology 43:1465-1467
11. Chu NS (1993) Early and late CT abnormalities in the persistent vegetative state due to cerebral anoxiaischemia. J Formos Med Assoc 92:697-701
12. deVolder AG, Goffmet AM, Bol A, Michel C, de Barsy Th, Laterre C (1990) Brain glucose metabolism in postanoxic syndrome. Arch Neurol 47:197-204
13. deVolder AG, Michel C, Guerit JM, Bol A, Georges B, de Barsy Th, Laterre C (1994) Brain glucose metabolism in postanoxic syndrome due to cardiac arrest. Acta Neurol Belg 94:183-189
14. Facco E, Munari M, Behr AU, Baratto BF, Zucchetta P, Bui F, Cesaro S, Giron GP (1998) Assessment of brain perfusion and comparison between SPECT and CT scan data: preliminary report. Neurol Res 20 (Suppl 1):S 40-43
15. Firsching R (1998) Moral dilemmas of tetraplegia: the "locked-in"-syndrome, the persistent vegetative state and brain death. Spinal Cord 36:741-743
16. Firsching R, Woischneck D, Klein S, Reißberg S, Döhring W, Peters B (2001) Classification of severe head injury based on magnetic resonance imaging. Acta Neurochir (Wien) 143:263-271
17. Fujioka M, Okuchi K, Sakaki T, Hiramatsu KI, Miyamoto S, Iwasaki S (1994) Specific changes in human brain following reperfusion after cardiac arrest. Stroke 25:2091-2095
18. Giacino JT, Ashwal S, Childs N, Cranford R, Jennett B, Katz DI, Kelly JP, Rosenberg JH, Whyte J, Zafonte RD, Zasler ND (2002) The minimally conscious state: definition and diagnostic criteria. Neurology 58:349-353
19. Grossman P, Hagel K (1996) Posttraumatic apallic syndrome following head injury. Part 1: clinical characteristics. Disabil Rehabil 18:1-20
20. Guerit JM (1994) The interest of multimodality evoked potentials in the evaluation of chronic coma. Acta Neurol Belg 94:174-182
21. Hackl JM, Gottardis M, Wieser C, Rumpl E, Stadler C, Schwarz, Monkayo R (1991) Endocrine abnormalities in severe traumatic brain injury - a cue to prognosis in severe craniocerebral trauma? Intensive Care Med 17:25-29
22. Hagel K, Rietz S (1998) Die Prognose des apallischen Syndroms. Der Anaesthesist 47:677-681
23. Harding B, Copp AJ (1997) Malformations. In: Graham DI, Lantos PL (eds) Greenfield's Neuropathology. Sixth Edition, 1997. Arnold Company London, S 459-460
24. Haupt WF, Prange HW, Janzen RWC (1997) Postanoxisches Koma. Akt Neurologie 24:103-109
25. Heiss WD, Grond M, Thiel A, Ghaemi M, Sobesky J, Rudolf J, Bauer B, Wienhard K (1998) Permanent cortical damage detected by flumazenil PET in acute stroke Stroke 29:454-461
26. Jennett B, Adams JH, Murray LS, Graham DI (2001) Neuropathology in vegetative and severely disabled patients after head injury. Neurology 56:486-490
27. Jennett B, Plum F (1972) Persistent vegetative state after brain damage: a syndrome in search of a name. Lancet 1:734-737
28. Kinney HC, Korein J, Panigrahy A, Dikkes P, Goode R (1994) Neuropathological findings in the brain of Karen Ann Quinlan. The role of the thalamus in the persistent vegetative state. N Engl J Med 330:1469-1475
29. Kinney HC, Samuels MA (1994) Neuropathology of the persistent vegetative state. A review. J Neuropathol Exp Neurol 53:548-558
30. Kretschmer E (1940) Das apallische Syndrom. Z. ges Neurol Psychiat 169:576-578
31. Krimchansky BZ, Sazbon L, Heller, L, Kosteff H, Luttwak Z (1999) Bladder tone in patients in post-traumatic vegetative state. Brain Inj 13:899-903
32. Kuwert T, Bartenstein P, Grtinwald F, Herholz K, Larisch R, Sabri O, Biersack HJ, Moser E, Müller-Gärtner H-W, Schober O, Schwaiger M, Büll U, Heiss WD (1998) Klinische Wertigkeit der Positronen-Emissions-Tomographie in der Neuromedizin. Nervenarzt 69:1045-1060
33. Lechleitner P, Felber G, Birbamer G, Saltuari L, Schinnerl A, Luef G, Aichner F (1992) Proton magnetic resonance spectroscopy of brain after cardiac resuscitation. Lancet 340:913
34. Levy DE, Sidtis JJ, Rottenberg DA, Jarden JO, Strother SC, Dhawan V, Ginos JZ, Tramo MJ, Evans AC, Plum F (1987) Differences in cerebral blood flow and glucose utilization in vegetative versus locked-in patients. Ann Neurol 22:673-682
35. Multi-Society Task Force on PVS (1993) Medical aspects of the persistent vegetative state. Parts 1 and 2. New Engl J Med 330:1499-1508, 1572-1579
36. Munno I, Damiani S, Scardapane R, Lacedra G, Megna M, Patrimo C, Megna GF (1998) Evaluation of hypothalamic-pituitary-adronocorticla hormones and inflammatory cytokines in patients with persistent vegetative state. Immunopharmacol Immunotoxicol 20:519-529
37. Nishioka H, Ito H, Ikeda Y, Koike S (1996) Hypothalamic-adrenohypophysial function of corticotropin-releasing hormone (CRH)-ACTH system in hypoxic coma. No T Shinkei 48:53-57
38. Oksenberg A, Arons E, Sazbon L, Mizrahi A, Radwan H (2000) Sleep-related erections in vegetative state patients. Sleep 23:953-957
39. Pentelényi T (1992) Significance of endocrine studies in the general assessment and prediction of fatal outcome in head injury. Acta Neurochir 52 (Suppl):21-24
40. Plum F, Posner JB (1980) The diagnosis of stupor and coma. Davis, Philadelphia, 3. Auflage
41. Quality Standards Subcommittee of the American Academy of Neurology (1995) Practice parameters: Assessment and management of patients in the persistent vegetative state. Neurology 45:1015-1018
42. Ricci R, Barbarella G, Musi P, Boldrini P, Trevisan C, Basaglia N (1997) Localised proton MR spectroscopy of brain metabolism changes in vegetative patients. Neuroradiology 39:313-319
43. Rudolf J, Beil C, Heiss WD (1993) Regional cerebral glucose metabolism in postanoxic syndrome: evidence of prognostic sensitivity? J Cereb Blood Flow Metab 13 (Suppl 1):S 391
44. Rudolf J, Haupt WF, Szelies B, Ghaemi M, Beil C, Heiss WD (1999) Regionaler Hirnstoffwechsel im postanoxischen coma vigile. Akt Neurologie 26:81-85
45. Rudolf J, Ghaemi M, Ghaemi Mo, Haupt WF, Szelies B, Heiss WD (1999) Cerebral glucose metabolism in acute and persistent vegetative state. J Neurosurg Anesthesiol 11:17-24
46. Rudolf J, Sobesky J, Grond M, Heiss WD (2000) Identification by positron emission tomography of neuronal loss in acute vegetative state. Lancet 358:115-116
47. Rupright J, Woods EA, Singh A (1996) Hypoxic brain injury: evaluation by single photon emission computed tomography. Arch Phys Med Rehabil 77:1205-1208
48. Sazbon L, Zagreba JR, Sozi P (1993) Course and outcome of patients in vegetative state of nontraumatic aetiology. J Neurol Neurosurg Psychiat 56:407-409
49. Shin DM, Ehrenberg B, Whyte J, Bach J, DeLisa JA: Evoked potential assessment: Utility in prognosis of chronic head injury. Arch Phys Med Rehabil (1989) 70:189-193
50. Tommasino C, Grana C, Lucignani G, Torri G, Fazio F (1995) Regional cerebral metabolism of glucose in comatose and vegetative state patients. J Neurosurg Anesthesiol 7:109-116
51. Voit T, Lemburg P, Neuen E, Lumenta C, Stork W (1987) Damage of thalamus and basal ganglia in asphyxiated full-term neonates. Neuropediatrics 18:176-181
52. Wade DT, Johnston, C (1999) The permanent vegetative state: practical guidance on diagnosis and management. Br Med J 319:841-844
53. Wallesch CW, Firsching R (1999) Apallisches Syndrom und andere komaähnliche Zustände. In: Hopf HC, Deuschl G, Diener HC, Reichmann H: Neurologie in Praxis und Klinik. Thieme, Stuttgart New York
54. Wienhard K, Wagner R, Heiss WD (1988) PET. Grundlagen und Anwendungen der Positronen-Emissions-Tomographie. Springer, Berlin Heidelberg New York
55. Wienhard K, Pawlik G, Nebeling B, Rudolf J, Fink G, Hamacher K, Stöcklin G, Heiss WD (1991) Estimation of local cerebral glucose utilization by positron emission tomography: Comparison of [18F]2-fluoro-2-deoxy-D-glucose and [18F]2-fluoro- 2-deoxy-D-mannose in patients with focal brain lesions. J Cereb Blood Flow Metab 11:485-491
56. Wiethölter S, Steube D (1997) Prognosestellung bei apallischem Syndrom: ist der Einsatz elektrophysiologischer Verfahren sinnvoll? Akt Neurol 24:114-118