A general approach for the prediction of the intestinal absorption of drugs: Regression analysis using the physicochemical properties and drug- membrane electrostatic interaction

Journal of Pharmaceutical Sciences

Volumn 87, Issue 8, 1998, Pages 960-966

  Sugawara, Mitsuru ^a   Takekuma, You ^a   Yamada, Harumi ^a   Kobayashi, Michiya ^a   Iseki, Ken ^a   Miyazaki, Katsumi ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOPHENAZONE; ACETANILIDE; AMITRIPTYLINE; ANTICONVULSIVE AGENT; BROMPHENIRAMINE; CAFFEINE; CARBAMAZEPINE; CHLORPHENIRAMINE; CLOMIPRAMINE; DOXYLAMINE; EPIRIZOLE; FENBUFEN; IMIPRAMINE; INDOLEACETIC ACID; INDOMETACIN; KETOPROFEN; LIDOCAINE; LOCAL ANESTHETIC AGENT; NAPROXEN; NONSTEROID ANTIINFLAMMATORY AGENT; OZAGREL; PHENAZONE; PHENIRAMINE; PROCHLORPERAZINE; PROMAZINE; SALICYLIC ACID; THEOPHYLLINE; TOLMETIN; TRICYCLIC ANTIDEPRESSANT AGENT; UNINDEXED DRUG;

ARTICLE; DRUG ABSORPTION; DRUG ADSORPTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROGEN BOND; INTESTINE ABSORPTION; LIPOPHILICITY; MALE; MEMBRANE PERMEABILITY; NONHUMAN; PARTITION COEFFICIENT; RAT;

EID: 0031877469     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1021/js970451q     Document Type: Article

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