Radiolabeled constructs for evaluation of the asialoglycoprotein receptor status and hepatic functional reserves

Bioconjugate Chemistry

Volumn 14, Issue 5, 2003, Pages 997-1006

  Abe, Michio ^a   Lai, Jing ^a   Kortylewicz, Zbigniew P ^a   Nagata, Hideo ^b   Fox, Ira J ^b   Enke, Charles A ^a   Baranowska Kortylewicz, Janina ^a,c  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b J Bruce Henriksen Laboratories   (United States)

^c NEBRASKA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CHELATION; MAMMALS;

ASIALOFETUIN; ASIALOGLYCOPROTEIN RECEPTORS; CLEARANCE RATES; FUNCTIONAL ACTIVITIES; HALF LIVES; HEPATOCYTES; IN-VIVO; LIVER TRANSPLANTATION; METABOLIC DISORDERS; NON-INVASIVE ASSESSMENTS;

CHEMICAL MODIFICATION;

2 IMINOTHIOLANE DERIVATIVE; ASIALOFETUIN; ASIALOGLYCOPROTEIN RECEPTOR; BUTYRIC ACID DERIVATIVE; CHELATING AGENT; GADOLINIUM 153; INDIUM 111; IODINE 125; N SULFOSUCCINIMIDYL 4 (4 MALEIMIDOPHENYL)BUTYRATE; PENTETIC ACID; POLYLYSINE; RADIOISOTOPE; REAGENT; SUCCINIMIDE DERIVATIVE; TECHNETIUM 99M; THIOL DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; CELL FUNCTION; CELL ISOLATION; CELL SURVIVAL; CELL TRANSPLANTATION; CONJUGATION; CONTROLLED STUDY; DRUG ABSORPTION; DRUG ELIMINATION; DRUG UPTAKE; EVALUATION; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; ISOTOPE LABELING; LIVER CELL; LIVER CLEARANCE; LIVER FAILURE; LIVER FUNCTION; LIVER METABOLISM; LIVER TRANSPLANTATION; MEASUREMENT; METABOLIC DISORDER; MOUSE; NONHUMAN; PLASMA CLEARANCE; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN METABOLISM; PROTEIN MODIFICATION; PROTEIN STABILITY; PROTEIN TARGETING; PROTEIN TRANSPORT; QUANTITATIVE ANALYSIS; RAT; RECEPTOR BINDING; SWINE; SYNTHESIS;

ANIMALIA; SUIDAE; SUS SCROFA;

EID: 0141458051     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc034081a     Document Type: Article

References (22)

1. Bohnen, N. I., Charron, M., Reyes, J., Rubinstein, W., Strom, S. C., Swanson, D., and Towbin, R. (2000) Use of indium-111-labeled hepatocytes to determine the biodistribution of transplanted hepatocytes through portal vein infusion. Clin. Nucl. Med. 25, 447-450.
2. Gupta, S., Lee, C. D., Vemuru, R. P., and Bhargava, K. K. (1994) 111Indium labeling of hepatocytes for analysis of short-term biodistribution of transplanted cells. Hepatology 19, 750-757.
3. Gupta, S., Yerneni, P. R., Vemuru, R. P., Lee, C. D., Yellin, E. L., and Bhargava, K. K. (1993) Studies on the safety of intrasplenic hepatocyte transplantation: relevance to ex vivo gene therapy and liver repopulation in acute hepatic failure. Hum. Gene. Ther. 4, 249-257.
4. Hawkins, R. A., Hall, T., Gambhir, S. S., Busuttil, R. W., Huang, S. C., Glickman, S., Marciano, D., Brown, R. K., and Phelps, M. E. (1988) Radionuclide evaluation of liver transplants. Semin. Nucl. Med. 18, 199-212.
5. Sakahara, H., Kiuchi, T., Nishizawa, S., Saga, T., Nakamoto, Y., Sato, N., Higashi, T., Tanaka, K., and Konishi, J. (1999) Asialoglycoprotein receptor scintigraphy in evaluation of auxiliary partial orthotopic liver transplantation. J. Nucl. Med. 40, 1463-1467.
6. Kudo, M., Todo, A., Ikekubo, K., Yamamoto, K., Vera, D. R., and Stadalnik, R. C. (1993) Quantitative assessment of hepatocellular function through in vivo radioreceptor imaging with technetium 99m galactosyl human serum albumin. Hepatology 17, 814-819.
7. Miki, K., Kubota, K., Inoue, Y., Vera, D. R., and Makuuchi, M. (2001) Receptor measurements via Tc-GSA kinetic modeling are proportional to functional hepatocellular mass. J. Nucl. Med. 42, 733-737.
8. Pimstone, N. R., Stadalnik, R. C., Vera, D. R., Hutak, D. P., and Trudeau, W. L. (1994) Evaluation of hepatocellular function by way of receptor-mediated uptake of a technetium-99m-labeled asialoglycoprotein analog. Hepatology 20, 917-923.
9. Rogers, J. C., and Kornfeld, S. (1971) Hepatic uptake of proteins coupled to fetuin glycopeptide. Biochem. Biophys. Res. Commun. 45, 622-629.
10. Morell, A. G., Irvine, R. A., Sternlieb, I., and Schneiberg, I. H. (1968) Physical and chemical studies on ceruloplasmin: V. Metabolic studies on sialic acid-free ceruloplasmin in vivo. J. Biol. Chem. 243, 155-159.
11. Morell, A. G., Gregoriadis, G., and Scheinberg, I. H. (1971) The role of sialic acid in determining the survival of glycoprotein in the circulation. J. Biol. Chem. 246, 1461-1467.
12. Roseng, L., Tolleshaug, H., and Berg, T. (1992) Uptake, intracellular transport, and degradation of poly(ethylene glycol)-modified asialofetuin in hepatocytes. J. Biol. Chem. 267, 22987-22993.
13. Abrams, M. J., Juweid, M., Tenkate, C. I., Schwartz, D. A., Hauser, M. M., Gaul, F. E., Fuccello, A. J., Rubin, R. H., Strauss, H. W., and Fischman, A. J. (1990) Technetium-99m-human polyclonal IgG radiolabeled via the hydrazino nicotinamide derivative for imaging focal sites of infection in rats. J. Nucl. Med. 31, 2022-2028.
14. Corson, D. T., and Meares, C. F. (2000) Efficient multigram synthesis of the bifunctional chelating agent (S)-1-p-isothiocyanatobenzyl-diethylenetriaminepentaacetic acid. Bioconjugate Chem. 11, 292-299.
15. Berry, M. N., and Friend, D. S. (1969) High yield preparation of isolate rat liver parenchymal cells: A biochemical and fine structural study. J. Cell Biol. 43, 506-520.
16. Seglen, P. O. (1976) Preparation of isolated rat liver cells. Methods Cell. Biol. 13, 29-83.
17. Baranowska-Kortylewicz, J., Dalrymple, G. V., Quadri, S. M., and Harrison, K. A. (1995) Radiolabeling of antibodies for therapy and diagnosis. Methods Mol. Biol. 51, 423-439.
18. Claessens, R. A., Boerman, O. C., Koenders, E. B., Oyen, W. J., van der Meer, J. W., and Corstens, F. H. (1996) Technetium-99m labeled hydrazinonicotinamido human non-specific polyclonal immunoglobulin G for detection of infectious foci: a comparison with two other technetium-labeled immunoglobulin preparations. Eur. J. Nucl. Med. 23, 414-421.
19. Fraker, P. J., and Speck, J. C., Jr. (1978) Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphenylglycoluril. Biochem. Biophys. Res. Commun. 80, 849-857.
20. Weigel, P. H., and Oka, J. A. (1983) The surface content of asialoglycoprotein receptors on isolated hepatocytes is reversibly modulated by changes in temperature. J. Biol. Chem. 258, 5089-5102.
21. Wu, J., Nantz, M. H., and Zern, M. A. (2002) Targeting hepatocytes for drug and gene delivery: emerging novel approaches and applications. Front. Biosci. 7d, 717-725.
22. Fiume, L., Di Stefano, G., Busi, C., Mattioli, A., Bonino, F., Torrani-Cerenzia, M., Verme, G., Rapicetta, M., Bertini, M., and Gervasi, G. B. (1997) Liver targeting of antiviral nucleoside analogues through the asialoglycoprotein receptor. J. Viral. Hepat. 4, 363-370.