Pharmacokinetics of isoflurane: Uptake in the body

Pharmacology

Volumn 69, Issue 3, 2003, Pages 132-137

  Lu, Chih Cherng ^a   Ho, Shung Tai ^a   Wong, Chih Shung ^a   Wang, Jhi Joung ^a,b   Tsai, Chien Song ^a   Hu, Oliver Yao Pu ^a   Chang, Sun Yran ^a   Lin, Chung Yuan ^c  

^a TRI SERVICE GENERAL HOSPITAL   (Taiwan)

^b CHI MEI MEDICAL CENTER   (Taiwan)

^c UNIVERSITY OF CHICAGO   (United States)

Author keywords

Anesthetics; Body uptake, isoflurane; Isoflurane; Pharmacokinetics

Indexed keywords

ANESTHETIC AGENT; FENTANYL; ISOFLURANE; LIDOCAINE; THIOPENTAL;

ADULT; AGED; ANESTHESIA; ARTERIAL BLOOD; ARTERY CATHETER; ARTICLE; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORONARY ARTERY BYPASS GRAFT; DRUG BLOOD LEVEL; DRUG UPTAKE; FEMALE; GAS CHROMATOGRAPHY; HEART OUTPUT; HUMAN; MALE; PRIORITY JOURNAL; PULMONARY ARTERY; THERMODILUTION;

AGED; ANESTHETICS, INHALATION; CARDIAC OUTPUT; CHROMATOGRAPHY, GAS; CORONARY ARTERY BYPASS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG THERAPY, COMBINATION; FEMALE; HUMANS; INHALATION; ISOFLURANE; MALE; PULMONARY ALVEOLI; PULMONARY ARTERY;

EID: 0141426733     PISSN: 00317012     EISSN: None     Source Type: Journal    
DOI: 10.1159/000072665     Document Type: Article

References (17)

1. Severinghaus JW: The rate of uptake of nitrous oxide in man. J Clin Invest 1954;33:1183-1189.
2. Severinghaus JW: Role of lung factors; in Paper EM, Kitz RJ (eds): Uptake and Distribution of Anesthetic Agents. New York, McGraw-Hill, 1963, chap 7, pp 72-78.
3. Lowe HJ: Clinical and laboratory evaluation of an expired anesthetic gas monitor (Narko-Test). Anesthesiology 1975;34:378-382.
4. Mapleson WW: Circulation-time models of the uptake of inhaled anaesthetics and data for quantifying them. Br J Anaesth 1973;45:319-334.
5. Lin CY: Uptake of anaesthetic gases and vapours. Anaesth Intensive Care 1994;22:363-373.
6. Riley RL, Crournand A: 'Ideal' alveolar air and the analysis of ventilation perfusion relationship in the lung. J Appl Physiol 1949;1:825-936.
7. Yang NC, Hwang KL, Hung DZ, Wuhh HH, Ho WM: Reliable gas chromatographic-mass spectrometric method combined with a head-space autosampler for isoflurane determination in blood. J Chromatogr B Biomed Sci Appl 2000;742:277-282.
8. Yang NC, Hwang KL, Shen CH, Wang HF, Ho WM: Simultaneous determination of fluorinated inhalation anesthetics in blood by gas chromatography-mass spectrometry combined with a headspace autosampler. J Chromatogr B Biomed Sci Appl 2001;759:307-318..
9. London MJ, Matson AM, Royston BD, Hewlett AM, White DC, Nunn JF: Components of the inspiratory-arterial isoflurane partial pressure difference. Br J Anaesth 1993;70:605-611.
10. Sun X-G, Su F, Shi YQ, Lee C: The 'second gas effect' is not a valid concept. Anesth Analg 1999;88:188-192.
11. 2O concentrations in essentially closed circuits. Anaesthesist 1977;26:514-517.
12. Lin CY, Mostert JW, Benson DW: Closed circle systems: A new direction in the practice of anesthesia. Acta Anaesthesiol Scand 1980;24:354-361.
13. Eger EI II: Halothane uptake in man at constant alveolar concentration. Anethesiology 1963;24:299-304.
14. Dwyer R, Fee JP, Clarke RS: End-tidal concentrations of halothane and isoflurane during induction of anaesthesia in young and elderly patients. Br J Anaesth 1990;64:36-41.
15. Dwyer RC, Fee JP, Howard PJ, Clarke RS: Arterial washin of halothane and isoflurane in young and elderly adult patients. Br J Anaesth 1991;66:572-579.
16. Frei FJ, Thomson DA, Zbinden AM: Influence of ventilatory and circulatory changes on the pharmacokinetics of halothane and isoflurane. Experientia 1988;44:178-181.
17. Zbinden AM, Thomson DA, Westenskow DR, Frei FJ, Maertens J: Anaesthetic uptake and elimination: Is there a difference between halothane and isoflurane in the dog? Br J Anaesth 1988;60:395-401.