Synthesis and biological evaluation of halo-neplanocin A as novel mechanism-based inhibitors of S-Adenosylhomocysteine hydrolase

Nucleosides, Nucleotides and Nucleic Acids

Volumn 22, Issue 5-8, 2003, Pages 589-592

  Jeong, Lak Shin ^a   Moon, Hyung Ryong ^a   Park, Jae Gyu ^a   Shin, Dae Hong ^a   Choi, Won Jun ^a   Lee, Kang Man ^a   Kim, Hea Ok ^b   Chun, Moon Woo ^b   Kim, Hee Doo ^c   Kim, Joong Hyup ^d  

^a Ewha Womans University   (South Korea)

^b Seoul National University   (South Korea)

^c Sookmyung Women's University   (South Korea)

^d Korea Institute of Science and Technology   (South Korea)

Author keywords

Halo neplanocin A; Mechanism based inhibitor; S Adenosylhomocysteine hydrolase

Indexed keywords

ADENOSYLHOMOCYSTEINASE; NEPLANOCIN A;

CATALYSIS; CONFERENCE PAPER; DERIVATIZATION; DRUG MECHANISM; DRUG SCREENING; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME INHIBITION; HALOGENATION; METHYLATION; SYNTHESIS;

ADENOSINE; ADENOSYLHOMOCYSTEINASE; ENZYME INHIBITORS; INDICATORS AND REAGENTS; KINETICS; MODELS, MOLECULAR; MOLECULAR CONFORMATION;

EID: 0141425747     PISSN: 15257770     EISSN: None     Source Type: Journal    
DOI: 10.1081/NCN-120021961     Document Type: Conference Paper

References (8)

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