Two sorts of problems on drug controlled release from swellable polymer

Shengwu Yixue Gongchengxue Zazhi/Journal of Biomedical Engineering

Volumn 20, Issue 1, 2003, Pages 17-21

  Li, Lingbing ^a   Tan, Yebang ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

Controlled release; Model; Swellable polymer; Viscoelastic stress

Indexed keywords

MATHEMATICAL MODELS; STRAIN; STRESSES; VISCOELASTICITY;

DRUG CONTROLLED RELEASE; SWELLABLE POLYMER; VISCOELASTIC STRESS;

POLYMERS;

POLYMER;

ARTICLE; CHEMICAL MODEL; CHEMISTRY; DELAYED RELEASE FORMULATION; DIFFUSION; DRUG DELIVERY SYSTEM; TABLET;

DELAYED-ACTION PREPARATIONS; DIFFUSION; DRUG DELIVERY SYSTEMS; MODELS, CHEMICAL; POLYMERS; TABLETS;

EID: 0043240432     PISSN: 10015515     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (6)

1. Siepmann J, Kranz H, Bodmeier R. HPMC-matrix for controlled drug delivery: a new model combining diffusion, swelling and dissolution mechanisms and predicting the release kinetics. Pharm Res, 1999, 16(11): 1748
2. Xu HW, Ding PT, Zheng JM. Mechanism of non-diffusion controlled drug release from polymeric systems. Acta Pharm Sinica, 2000; 35(9): 710
3. Ritger PL, Peppas NA. A simple equation for description of solute release. II. Fickian and anomalous release from swellable devices. J Controlled Release, 1987; 5(1): 37
4. Peppas NA. Release of bioactive agents from swellable polymers. In: Anderson JM, Kim SW, eds. Recent advances in drug delivery system. New York and London: Plenum Press, 1984: 279-290
5. Hariharan D, Peppas NA. Modeling of water transport and solute release in physiologically sensitive gels. J Controlled Release, 1993; 23(2): 23
6. Li LB, Xu MY. Study on non-fickian diffusion in glassy polymer. Chinese J Biomedical Engineering, 1999; 18(4): 441