Molecular dosimetry of N7-(2-hydroxypropyl)guanine in tissues of F344 rats after inhalation exposure to propylene oxide

Carcinogenesis

Volumn 24, Issue 7, 2003, Pages 1233-1238

  Ríos Blanco, Melva N ^a,c   Ranasinghe, Asoka ^a   Lee, Moung S ^b   Faller, Thomas ^b   Filser, Johannes G ^b   Swenberg, James A ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

^c Global Personal Care and Skin Health R D   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

7 (2 HYDROXYETHYL)GUANINE; CARCINOGEN; DNA; PROPYLENE OXIDE;

AIRBORNE PARTICLE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; CANCER INCIDENCE; CARCINOGENIC ACTIVITY; CELL PROLIFERATION; CHEMICAL CARCINOGENESIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA ALKYLATION; DNA DETERMINATION; DOSIMETRY; EXPOSURE; GAS CHROMATOGRAPHY; INHALATION; LINEAR SYSTEM; LIVER; LUNG; MALE; MASS SPECTROMETRY; NONHUMAN; NOSE MUCOSA; NOSE TUMOR; PRIORITY JOURNAL; RAT; RAT STRAIN; TARGET ORGAN; VAPOR; WORKPLACE;

ALKYLATION; ANIMALS; CARCINOGENS; DNA; DNA ADDUCTS; EPOXY COMPOUNDS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; GUANINE; INCIDENCE; INHALATION EXPOSURE; LIVER; LUNG; MALE; NASAL MUCOSA; RATS; RATS, INBRED F344; RISK FACTORS;

EID: 0043171132     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/bgg087     Document Type: Article

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