Hepatocellular carcinoma associated with secondary haemochromatosis in non-cirrhotic liver: A case report

Hepatology Research

Volumn 26, Issue 3, 2003, Pages 254-258

  Chung, Hobyung ^a   Kudo, Masatoshi ^a   Kawasaki, Toshihiko ^a   Kitano, Masayuki ^a   Minami, Yasunori ^a   Suetomi, Youichirou ^a   Onda, Hirokazu ^a  

^a KINKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Hepatocellular carcinoma; Secondary haemochromatosis; Transarterial chemoembolization

Indexed keywords

HEMOSIDERIN;

ADULT; ARTICLE; ARTIFICIAL EMBOLISM; CANCER GRADING; CASE REPORT; DISEASE ASSOCIATION; ERYTHROCYTE TRANSFUSION; HEMOCHROMATOSIS; HUMAN; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; LIVER NODULE; LIVER PARENCHYMA; MALE; MYELODYSPLASTIC SYNDROME; NEEDLE BIOPSY; PANCYTOPENIA; PRIORITY JOURNAL;

EID: 0043169700     PISSN: 13866346     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1386-6346(03)00109-8     Document Type: Article

References (18)

1. Liver Cancer Study Group of Japan. Survey and follow-up study of primary liver cancer in Japan, Acta Hepatol. Jpn. 2000;41:799-811.
2. Meneghini H. Iron homeostasis, oxidative stress, and DNA damage. Free Radic Biol Med 1997;23:783-92.
3. Okada S. Iron and carcinogenesis in laboratory animals and humans: a mechanistic consideration and a review of literature. Int J Oncol 1998;3:191-203.
4. Eriksson LC, Stal P. Experimental studies on the role of iron in liver tumor development. In: Hallberg L, Nils-Georg A, editors. Iron Nutrition in Health and Disease. London: John Libbey and Co, 1996:285-92.
5. Niederau C, Fisher R, Sonnenberg A, et al. Survival and causes of death in cirrhotic and in non-cirrhotic patients with primary haemochromatosis. N Engl J Med 1985;313:1256-62.
6. Feder JN, Gnirke A, Thomas W, et al. A novel MHC class I-like gene is mutated in patients with hereditary hemochromatosis. Nat Genet 1996;13:399-408.
7. Merryweather-Clarke AT, Pointon JJ, Shearman JD, et al. Global prevalence of putative hemochromatosis mutation. J Med Genet 1997;34:275-8.
8. Sohda T, Yanai J, Soejima H, et al. Frequencies in the Japanese population of HFE gene mutations. Biochem Genet 1999;37:63-8.
9. Thomas JD, Louredo A, Turegano F, et al. Hepatocellular carcinoma in a non-cirrhotic coal miner with secondary haemochromatosis. Eur J Gastroenterol Hepatol 1997;9:633-4.
10. Nakagawa K, Suzuki M, Unno M, et al. A case of hepatocellular carcinoma with erythropoietic hemochromatosis due to myelodysplastic syndrome. Acta Hepatol Jpn 2000;41:823-8.
11. Blumberg RS, Chopra S, Ibrahim R, et al. Primary hepatocellular carcinoma in idiopathic hemochromatosis after reversal of cirrhosis. Gastroenterology 1988;95:1399-402.
12. Fellows IW, Stewart M, Jeffcoate WJ, et al. Hepatocellular carcinoma in primary haemochromatosis in the absence of cirrhosis. Gut 1988;29:1603-6.
13. Deugnier YM, Guyader D, Crantock L, et al. Primary liver cancer in genetic hemochromatosis: a clinical, pathological, and pathogenic study of 54 cases. Gastroenterology 1993;104:228-34.
14. Gleeson D, Newbould MJ, Taylor P, et al. Androgen associated hepatocellular carcinoma with an aggressive course. Gut 1991;32:1084-6.
15. Seip M. Malignant tumors in two patients with Diamond-Black-fan anemia treated with corticosteroids and androgens. Pediatr Hematol Oncol 1994;11:423-6.
16. Moldvay J, Schaff Z, Lapis K. Hepatocellular carcinoma in Fanconi's anemia treated with androgen and corticosteroid. Zentralbl Pathol 1991;137:167-70.
17. Esterbauser H. Cytotoxicity and genotoxicity of lipid-peroxidation products. Am J Clin Nutr 1993;57:779-86.
18. Dreher D, Junod AF. Role of oxygen free radicals in cancer development. Eur J Cancer A 1996;32:30-8.