Activation of phospholipase D by the small GTPase Sar1p is required to support COPII assembly and ER export

EMBO Journal

Volumn 22, Issue 16, 2003, Pages 4059-4069

  Pathre, Purnima ^a   Shome, Kuntala ^a   Blumental Perry, Anna ^a   Bielli, Anna ^a   Haney, Charles J ^a   Alber, Sean ^a   Watkins, Simon C ^a   Romero, Guillermo ^a   Aridor, Meir ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

COPII; Endoplasmic reticulum; PLD; Sar1p

Indexed keywords

GUANOSINE TRIPHOSPHATASE; PHOSPHOLIPASE D; PROTEIN; PROTEIN COPII; PROTEIN SAR1P; PROTEIN SEC13; PROTEIN SEC23; PROTEIN SEC24; PROTEIN SEC31; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; COMPLEX FORMATION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; ENZYME ACTIVITY; LIPID COMPOSITION; MAMMAL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; RAT;

1-BUTANOL; ANIMALS; BIOLOGICAL TRANSPORT; CARRIER PROTEINS; CELL LINE; COP-COATED VESICLES; ENDOPLASMIC RETICULUM; FIBROBLASTS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GUANOSINE TRIPHOSPHATE; MEMBRANE PROTEINS; MONOMERIC GTP-BINDING PROTEINS; NUCLEAR PORE COMPLEX PROTEINS; PHOSPHOLIPASE D; PHOSPHOPROTEINS; RATS; SACCHAROMYCES CEREVISIAE PROTEINS; VESICULAR STOMATITIS-INDIANA VIRUS; VESICULAR TRANSPORT PROTEINS;

ANIMALIA; MAMMALIA;

EID: 0042967993     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdg390     Document Type: Article

References (41)

1. Allan, D. (1996) Mapping the lipid distribution in the membranes of BHK cells (mini-review). Mol. Membr. Biol., 13, 81-84.
2. Antonny, B. and Schekman, R. (2001) ER export: public transportation by the COPII coach. Curr. Opin. Cell Biol., 13, 438-443.
3. Aridor, M. and Balch, W.E. (2000) Kinase signaling initiates coat complex II (COPII) recruitment and export from the mammalian endoplasmic reticulum. J. Biol. Chem., 275, 35673-35676.
4. Aridor, M. and Traub, L.M. (2002) Cargo selection in vesicular transport: the making and breaking of a coat. Traffic, 3, 537-546.
5. Aridor, M., Bannykh S., Rowe, T. and Balch, W.E. (1995) Sequential coupling between COPII and COPI vesicle coats in endoplasmic reticulum to Golgi transport. J. Cell Biol., 131, 875-893.
6. Aridor, M., Weissman, J., Bannykh, S., Nuoffer, C. and Balch, W.E. (1998) Cargo selection by the COPII budding machinery during export from the ER. J. Cell Biol., 141, 61-70.
7. Aridor, M., Fish, K.N., Bannykh, S., Weissman, J., Roberts, T.H., Lippincott-Schwartz, J. and Balch, W.E. (2001) The Sar1 GTPase coordinates biosynthetic cargo selection with endoplasmic reticulum export site assembly. J. Cell Biol., 152, 213-229.
8. Bi, K., Roth, M.G. and Ktistakis, N.T. (1997) Phosphatidic acid formation by phospholipase D is required for transport from the endoplasmic reticulum to the Golgi complex. Curr. Biol., 7, 301-307.
9. Bi, X., Corpina, R.A. and Goldberg, J. (2002) Structure of the Sec23/24-Sar1 pre-budding complex of the COPII vesicle coat. Nature, 419, 271-277.
10. Cockcroft, S., Bi, K., Ktistakis, N.T. and Roth, M.G. (2001) Biological properties and measurement of phospholipase D activation by ADP-ribosylation factor (ARF). Methods Enzymol., 329, 355-372.
11. de Figueiredo, P., Drecktrah, D., Katzenellenbogen, J.A., Strang, M. and Brown, W.J. (1998) Evidence that phospholipase A2 activity is required for Golgi complex and trans Golgi network membrane tubulation. Proc. Natl Acad. Sci. USA, 95, 8642-8647.
12. de Figueiredo, P., Drecktrah, D., Polizotto, R.S., Cole, N.B., Lippincott-Schwartz, J. and Brown, W.J. (2000) Phospholipase A2 antagonists inhibit constitutive retrograde membrane traffic to the endoplasmic reticulum. Traffic, 1, 504-511.
13. Dominguez, M., Dejgaard, K., Fullekrug, J., Dahan, S., Fazel, A., Paccaud, J.P., Thomas, D.Y., Bergeron, J.J. and Nilsson, T. (1998) gp25L/emp24/p24 protein family members of the cis-Golgi network bind both COP I and II coatomer. J. Cell Biol., 140, 751-765.
14. Godi, A., Pertile, P., Meyers, R., Marra, P., Di Tullio, G., Iurisci, C., Luini, A., Corda, D. and De Matteis, M.A. (1999) ARF mediates recruitment of PtdIns-4-OH kinase-β and stimulates synthesis of PtdIns(4,5)P2 on the Golgi complex. Nat. Cell Biol., 1, 280-287.
15. Iyer, S.S. and Kusner, D.J. (1999) Association of phospholipase D activity with the detergent-insoluble cytoskeleton of U937 promonocytic leukocytes. J. Biol. Chem., 274, 2350-2359.
16. Kuehn, M.J., Herrmann, J.M. and Schekman, R. (1998) COPII-cargo interactions direct protein sorting into ER-derived transport vesicles. Nature, 391, 187-190.
17. Lee, T.H. and Linstedt, A.D. (2000) Potential role for protein kinases in regulation of bidirectional endoplasmic reticulum-to-Golgi transport revealed by protein kinase inhibitor H89. Mol. Biol. Cell, 11, 2577-2590.
18. Lippincott-Schwartz, J., Roberts, T.H. and Hirschberg, K. (2000) Secretory protein trafficking and organelle dynamics in living cells. Annu. Rev. Cell Dev. Biol., 16, 557-589.
19. Liscovitch, M., Czarny, M., Fiucci, G., Lavie, Y. and Tang, X. (1999) Localization and possible functions of phospholipase D isozymes. Biochim. Biophys. Acta, 1439, 245-263.
20. Matsuoka, K., Morimitsu, Y., Uchida, K. and Schekman, R. (1998a) Coat assembly directs v-SNARE concentration into synthetic COPII vesicles. Mol. Cell, 2, 703-708.
21. Matsuoka, K., Orci, L., Amherdt, M., Bednarek, S.Y., Hamamoto, S., Schekman, R. and Yeung, T. (1998b) COPII-coated vesicle formation reconstituted with purified coat proteins and chemically defined liposomes. Cell, 93, 263-275.
22. Mizoguchi, T., Nakajima, K., Hatsuzawa, K., Nagahama, M., Hauri, H.P., Tagaya, M. and Tani, K. (2000) Determination of functional regions of p125, a novel mammalian Sec23p-interacting protein. Biochem. Biophys. Res. Commun., 279, 144-149.
23. Nagaya, H., Wada, I., Jia, Y.J. and Kanoh, H. (2002) Diacylglycerol kinase δ suppresses ER-to-Golgi traffic via its SAM and PH domains. Mol. Biol. Cell, 13, 302-316.
24. Nufer, O., Guldbrandsen, S., Degen, M., Kappeler, F., Paccaud, J.P., Tani, K. and Hauri, H.P. (2002) Role of cytoplasmic C-terminal amino acids of membrane proteins in ER export. J. Cell Sci., 115, 619-628.
25. Plutner, H., Davidson, H.W., Saraste, J. and Balch, W.E. (1992) Morphological analysis of protein transport from the ER to Golgi membranes in digitonin-permeabilized cells: role of the P58 containing compartment. J. Cell Biol., 119, 1097-1116.
26. Provost, J.J., Fudge, J., Israelit, S., Siddiqi, A.R. and Exton, J.H. (1996) Tissue-specific distribution and subcellular distribution of phospholipase D in rat: evidence for distinct RhoA- and ADP-ribosylation factor (ARF)-regulated isoenzymes. Biochem. J., 319, 285-291.
27. Rowe, T. and Balch, W.E. (1995) Expression and purification of mammalian Sar1. Methods Enzymol., 257, 49-53.
28. Rowe, T., Aridor, M., McCaffery, J.M., Plutner, H., Nuoffer, C. and Balch, W.E. (1996) COPII vesicles derived from mammalian endoplasmic reticulum microsomes recruit COPI. J. Cell Biol., 135, 895-911.
29. Rudge, S.A., Cavenagh, M.M., Kamath, R., Sciorra, V.A., Morris, A.J., Kahn, R.A. and Engebrecht, J. (1998) ADP-ribosylation factors do not activate yeast phospholipase Ds but are required for sporulation. Mol. Biol. Cell, 9, 2025-2036.
30. Rudge, S.A., Pettitt, T.R., Zhou, C., Wakelam, M.J. and Engebrecht, J.A. (2001) SPO14 separation-of-function mutations define unique roles for phospholipase D in secretion and cellular differentiation in Saccharomyces cerevisiae. Genetics, 158, 1431-1444.
31. Schekman, R. and Orci, L. (1996) Coat proteins and vesicle budding. Science, 271, 1526-1533.
32. Schmidt, A., Wolde, M., Thiele, C., Fest, W., Kratzin, H., Podtelejnikov, A.V., Witke, W., Huttner, W.B. and Soling, H.D. (1999) Endophilin I mediates synaptic vesicle formation by transfer of arachidonate to lysophosphatidic acid. Nature, 401, 133-141.
33. Shome, K., Nie, Y. and Romero, G. (1998) ADP-ribosylation factor proteins mediate agonist-induced activation of phospholipase D. J. Biol. Chem., 273, 30836-30841.
34. Siddhanta, A., Backer, J.M. and Shields, D. (2000) Inhibition of phosphatidic acid synthesis alters the structure of the Golgi apparatus and inhibits secretion in endocrine cells. J. Biol. Chem., 275, 12023-12031.
35. Simonsen, A., Wurmser, A.E., Emr, S.D. and Stenmark, H. (2001) The role of phosphoinositides in membrane transport. Curr. Opin. Cell Biol., 13, 485-492.
36. Springer, S. and Schekman, R. (1998) Nucleation of COPII vesicular coat complex by endoplasmic reticulum to Golgi vesicle SNAREs. Science, 281, 698-700.
37. Springer, S., Spang, A. and Schekman, R. (1999) A primer on vesicle budding. Cell, 97, 145-148.
38. Tani, K., Mizoguchi, T., Iwamatsu, A., Hatsuzawa, K. and Tagaya, M. (1999) p125 is a novel mammalian Sec23p-interacting protein with structural similarity to phospholipid-modifying proteins. J. Biol. Chem., 274, 20505-20512.
39. Votsmeier, C. and Gallwitz, D. (2001) An acidic sequence of a putative yeast Golgi membrane protein binds COPII and facilitates ER export. EMBO J., 20, 6742-6750.
40. Weigert, R. et al. (1999) CtBP/BARS induces fission of Golgi membranes by acylating lysophosphatidic acid. Nature, 402, 429-433.
41. Weissman, J.T., Plutner, H. and Balch, W.E. (2001) The mammalian guanine nucleotide exchange factor mSec12 is essential for activation of the Sar1 GTPase directing endoplasmic reticulum export. Traffic, 2, 465-475.