Study of apolipoproteinc3 Sstl polymorphism in healthy volunteers from Northern India

Indian Journal of Clinical Biochemistry

Volumn 18, Issue 2, 2003, Pages 34-38

  Chhabra, S ^a   Agarwal, D P ^c   Vasisht, S ^a   Luthra, K ^a   Narang, R ^a   Manchanda, S C ^a   Srivastava, L M ^b   Das, Nibhriti ^a  

^a ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

^b SIR GANGA RAM HOSPITAL   (India)

^c NONE

Author keywords

APOC3; CAD; Hypertriglyceridemia; India; Sstl polymorphism

Indexed keywords

APOLIPOPROTEIN C3;

ADULT; ALLELE; ARTICLE; CORONARY ARTERY DISEASE; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; HUMAN; HYPERTRIGLYCERIDEMIA; INDIA; NORMAL HUMAN; VOLUNTEER;

EID: 0042933862     PISSN: 09701915     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02867365     Document Type: Article

References (30)

1. Jong, M.C., Hofker, M.H., Havekes, L.M. (1999) Role of ApoCs in Lipoprotein Metabolism Functional Differences Between ApoC1, ApoC2, and ApoC3. Arterioscler. Thromb. Vasc. Biol. 19, 472-484.
2. Paul-Hayase, H., Rosseneu, M., Robinson, D., van Bervliet, J.P., Deslypere, J.P. and Humphries, S.E. (1992) Polymorphisms in the apolipoprotein (apo) AI-CIII-AIV gene cluster: detection of genetic variation determining plasma apo Al, apo CIII and apo AIV concentrations. Hum. Genet. 88, 439-446.
3. Rees, A., Shoulders, C.C., Stocks, J., Galton, D.J. and Baralle, F.E. (1983)DNA polymorphism adjacent to human apolipoprotein A-1 gene: relation to hypertriglyceridemia. Lancet 1, 444-446.
4. Ko, Y.L., Ko, Y.S., Wu, S.M., Teng, M.S., Chen, F.R., Hsu, T.S., Chiang, C.W. and Lee, Y.S. (1997) Interaction between obesity and genetic polymorphisms in the apolipoprotein CIII gene and lipoprotein lipase gene on the risk of hypertriglyceridemia in Chinese. Hum. Genet. 100, 327-333.
5. Ahn, Y.I., Valdez, R., Reddy, A.P., Cole, S.A., Weiss, K.M. and Ferrell R.E. (1991) DNA polymorphisms of the apolipoprotein AI/CIII/AIV gene cluster influences plasma cholesterol and triglyceride levels in the Mayans of the Yucatan peninsula, Mexico. Hum. Hered. 41, 281-289.
6. Zeng, Q., Dammerman, M., Takada, Y., Matsunaga, A., Breslow, J.L. and Sasaki J. (1995) An apolipoprotein CIII marker associated with hypertriglyceridemia in Caucasians also confers increased risk in a west Japanese population. Hum. Genet. 95, 371-375.
7. Bai, H., Saku, K., Liu, R., Imamura, M. and Arakawa, K. (1995) Association between coronary heart disease and the apolipoprotein A-I/C-III/ A-IV complex in a Japanese population. Hum. Genet. 95, 102-104.
8. Rees, A., Stocks, J., Paul, H., Ohuchi, Y. and Galton D. (1986) Haplotypes identified by DNA polymorphisms at the apolipoprotein A-I and C-III loci and hypertriglyceridemia: a study in a Japanese population. Hum. Genet. 72, 168-171.
9. Hong, S.H., Park, W.H., Lee, C.C., Hong, J.H. and Kim, J.Q. (1997) Association between genetic variations of apo AI-CIII-AIV cluster gene and hypertriglyceridemic subjects. Clin. Chem. 43, 13-17.
10. Wu, J.H., Kao, J.T., Wen, M.S. and Lo, S.K. (2000) DNA polymorphisms at the apolipoprotein A1-CIII loci in Taiwanese: correlation of plasma APOCIII with triglyceride level and body mass index. J. Formos. Med. Assoc. 99, 367-374.
11. Tas, S. (1989) Strong association of a single nucleotide substitution in the 3′-untranslated region of the apolipoprotein C-III gene with common hypertriglyceridemia in Arabs. Clin Chem 35, 256-259.
12. Johansen, K., Dunn, B., Tan, J.C.Y., Kwassi, A.A., Skootnicki, A., and Skootnicki, M. (1991) Coronary artery disease and apolipoprotein AI-CIII gene polymorphism: a study of Saudi Arabians. Clin. Genet. 39, 1-5.
13. Rees, A., Stocks, J., Sharpe, C.R., Vella, M.A., Shoulders, C.C., Katz, J., Jowett, N.I., Barelle, F.E. and Galton, D.J. (1985) Deoxyribonucleic acid polymorphism in the apolipoprotein A-1-C-III gene cluster. J. Clin. Invest. 76, 1090-1095.
14. Tybjaerg-Hansen, A., Nordestgaard, B.G., Gerdes, L.U., Faergeman, O., Humphries, S.E. (1993) Genetic markers in the apo AI-CIII-AIV gene cluster for combined hyperlipidemia, hypertriglyceridemia, and predisposition to atherosclerosis. Atherosclerosis 100, 157-169.
15. Hoffer, M. J. V., Sijbrands, E.J.G., de Man, F.H.A.F., Havekes, L. M., Smelt, A.H.M. and Frants, R. (1998) Increased risk for endogenous hypertriglyceridaemia is associated with an apolipoprotein C3 haplotype specified by the Sstl polymorphism. Eur. J. Clin. Invest. 28, 807-812.
16. Aalto-Setala, K., Kontula, K., Sane, T., Nieminen, M., and Nikkila, E. (1987) DNA polymorphism of apolipoprotein A-I/C-III and insulin genes in familial hypertriglyceridemia and coronary heart disease. Atherosclerosis 66, 145-152.
17. Price, W.H., Morris, S.W., Burgon, R., Donald, P.M., and Kitchin, A.H. (1986) Apolipoprotein CIII polymorphism and coronary heart disease. Lancet 2, 1041.
18. Dammerman, M., Sandkuijl, L.A., Halaas, J.L., Chung, W. and Breslow J.L. (1993) An apolipoprotein CIII haplotype protective against hypertriglyceridemia is specified by promoter and 3′untranslated region polymorphisms. Proc. Natl. Acad. Sci. USA 90, 4562-4566.
19. Marcil, M., Boucher, B., and Gagne, E., Davignon, J., Hayden, M., and Jenest, J. (1996) Lack of association of the apolipoprotein A-I-C-III-A-IV gene Xmnl and Sstl polymorphisms and of the lipoprotein lipase gene mutations in familial combined hyperlipoproteinemia in French Canadian subjects. J. Lipid Res. 37, 309-319.
20. Dallinga-Thie, G.M., Bu, X.D., van Linde-Sibenius Trip, M., Rotter, J.I., Lusis, A.J., and de Bruin, T.W.A. (1996) Apolipoprotein A-I/C-III/A-IV gene cluster in familial combined hyperlipidemia: effects on LDL-cholesterol and apolipoproteins B and C-III. J. Lipid Res. 37, 136-147.
21. Dallinga-Thie, G.M., van Linde-Sibenius Trip, M., Rotter, J.I., Cantor, R.M., Bu, X.-D., Lusis, A.J. and de Bruin, T.W.A. (1997) Complex genetic contribution of the Apo AI-CIII-AIV gene cluster to familial combined hyperlipidemia. Identification of different susceptibility haplotypes. J. Clin. Investig. 99, 953-961.
22. Shoulders, C.C., Grantham, T.T., North, J.D., Gaspardone, A., Tomai, F., de Fazio, A., Versaci, F., Gioffre, P.A. and Cox, N.J. (1996) Hypertriglyceridemia and the apolipoprotein CIII gene locus: lack of association with the variant insulin response element in Italian school children. Hum. Genet. 98, 557-566.
23. Shoulders, C.C., Harry, P.J., Lagrost, L., White, S.E., Shah, N.F., North, J.D., Gilligan, M., Gambert, P., and Ball, M.J. (1991) Variation at the apo AI/CIII/AIV gene complex is associated with elevated plasma levels of apo CIII. Atherosclerosis 87, 239-247.
24. Enas E.A. and Mehta J.L. (1995) Malignant coronary artery disease in young Asian Indians. Thoughts on pathogenesis, prevention and therapy. New Engl. J. Med. 333, 1301-1307.
25. Chhabra, S., Narang, R., Krishnan, L.R., Vasisht, S., Agarwal, D.P., Srivastava, L.M., Manchanda, S.C. and Das, N (2002). Apolipoprotein C3 Sstl polymorphism and triglyceride levels in Asian Indians. BMC Genetics 3, 9.
26. Ferns, G. A. A., Ritchie, C., Stocks, J. and Galton, D. J. (1985) Genetic polymorphisms of apolipoprotein CIII and insulin in survivors of myocardial infarction. Lancet ii, 300-303.
27. Deeb, S., Failor, A., Brown, B.G., Brunzell, J.D., Albers, J.J. and Motulsky, A.G. (1986) Molecular genetics of apolipoproteins and coronary heart disease. Cold spring harbor symp. Quant Biol. 51, 403-409.
28. Rees, A., Stocks, J., Williams, L.G., Caplin, J.L., Jowett, N.I., Camm, A.J. and Galton D.J. (1985) DNA polymorphisms in the apolipoprotein CIII and insulin genes and atherosclerosis. Atherosclerosis 58, 269-275.
29. Paul, H., Galton, D. and Stocks, J. (1987) DNA polymorphic patterns and haplotype arrangements of apoA-1, apoC-III, apoA-IV gene cluster in different ethnic groups. Hum. Genet. 75, 264-268.
30. Esterbauer, H., Hell, E., Krimpler, F. and Wolfgang, P. (1999) Allele specific differences in apolipoprotein CIII mRNA expression in human liver. Clin. Chem. 45, 331-339.