Upregulation of lymphotoxin β expression in liver progenitor (oval) cells in chronic hepatitis C

Gut

Volumn 52, Issue 9, 2003, Pages 1327-1332

  Lowes, K N ^a,b   Croager, E J ^c   Abraham, L J ^c   Olynyk, J K ^b,c   Yeoh, G C T ^a,c  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^c UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

LYMPHOTOXIN; MESSENGER RNA; TUMOR NECROSIS FACTOR;

ARTICLE; CELL DIFFERENTIATION; CELL TYPE; CLINICAL ARTICLE; CONTROLLED STUDY; HEPATITIS C; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFLAMMATORY CELL; LIVER BIOPSY; LIVER CELL; LIVER CIRRHOSIS; LIVER DISEASE; LIVER FIBROSIS; LIVER INJURY; LIVER REGENERATION; LIVER RESECTION; LIVER TRANSPLANTATION; PATHOGENESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; STEM CELL;

GENE EXPRESSION REGULATION; HEPATITIS C, CHRONIC; HEPATOCYTES; HUMANS; LIVER CIRRHOSIS; LYMPHOTOXIN-ALPHA; POLYMERASE CHAIN REACTION; RNA, MESSENGER; STEM CELLS;

EID: 0042887513     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.52.9.1327     Document Type: Article

References (39)

1. Lowes KN, Brennan BA, Yeoh GC, et al. Oval cell numbers in human chronic liver diseases are directly related to disease severity. Am J Pathol 1999;154:537-41.
2. Vessey CJ, Hall PM. Hepatic stem cells: a review. Pathology 2001;33:130-41.
3. Sell S. Heterogeneity and plasticity of hepatocyte lineage cells. Hepatology 2001;33:738-50.
4. Knight B, Yeoh GCT, Husk KL, et al. Impaired preneoplatic changes and liver tumour formation in tumour necrosis factor receptor type 1 knockout mice. J Exp Med 2000;192:1809-18.
5. Evarts RP, Hu Z, Fujio K, et al. Activation of the hepatic stem cell compartment in the rat: role of transforming growth factor, hepatocyte growth factor, and acidic fibroblast growth factor in early proliferation. Cell Growth Diff 1993;4:555-61.
6. Matsusaka S, Tsujimura T, Toyosaka A, et al. Role of c-kit receptor tyrosine kinase in development of oval cells in rat 2-acetylaminofluorene/partial hepatectomy model. Hepatology 1999;29:670-6.
7. Hu Z, Evarts RP, Fujio K, et al. Expression of transforming growth factor alpha/epidermal growth factor receptor, hepatocyte growth factor/c-met and acidic fibroblast growth factor/fibroblast growth factors during hepatocarcinogenesis. Carcinogenesis 1996;17:931-8.
8. Bisgaard HC, Muller S, Nagy P, et al. Modulation of the gene network connected to IFN-γ in liver regeneration from oval cells. Am J Pathol 1999;155:1075-85.
9. Nagy P, Kiss A, Schnur J, et al. Dexamethasone inhibits the proliferation of hepatocytes and oval cells but not bile duct cells in rat liver. Hepatology 1998;28:423-9.
10. Voon DC, Subrata LS, Abraham LJ. Regulation of lymphotoxin β by turnout necrosis factor, phorbol myristate acetate, and ionomycin in Jurkat T cells. J Interferon Cytokine Res 2001;21:921-30.
11. Browning JL, Ngam-ek A, Lawton P, et al. Lymphotoxin β, a novel member of the TNF family that forms a heteromeric complex with lymphotoxin α on the cell surface. Cell 1993;72:847-56.
12. Rennert PD, Browning JL, Mebius R, et al. Surface lymphotoxin alpha/beta complex is required for the development of peripheral lymphoid organs. J Exp Med 1996;184:1999-2006.
13. Koni PA, Sacca R, Lawton P, et al. Distinct roles in lymphoid organogenesis for lymphotoxin α and β revealed in lymphotoxin β-deficient mice. Immunity 1997;6:491-500.
14. Iizuka K, Chaplin DD, Wang Y, et al. Requirement for membrane lymphotoxin in natural killer cell development. Proc Natl Acad Sci U S A 1999;96:6336-40.
15. Wu Q, Wang Y, Wang J, et al. The requirement of membrane lymphotoxin rot the presence of dendritic cells in lymphoid tissues. J Exp Med 1999;190:629-38.
16. Elewaut D, Brossay L, Santee SM, et al. Membrane lymphotoxin is required for the development of different subpopulations of NK T cells. J Immunol 2000;165:671-9.
17. VanArsdale TL, VanArsdale SL, Force WR, et al. Lymphotoxin β receptor signalling complex: Role of tumour necrosis factor receptor-associated factor 3 recruitment in cell death and activation of NF-κB. Proc Natl Acad Sci U S A 1997;94:2460-5.
18. Nakano H, Oshima H, Chung W, et al. TRAF5, an activator of NF-κB and putative signal transducer for the lymphotoxin receptor. J Biol Chem 1996;271:14661-4.
19. Degli-Esposti MA, Davis-Smith T, Din WS, et al. Activation of the lymphotoxin β receptor by cross-linking induces chemokine production and growth arrest in A375 melanoma cells. J Immunol 1997;158:1756-62.
20. Ngo VN, Korner H, Gunn MD, et al. Lymphotoxin alpha/beta and tumour necrosis factor are required for stromal cell expression of homing chemokines in B and T cell areas of the spleen. J Exp Med 1999;189:403-12.
21. You LR, Chen CM, Lee YH. Hepatitis C virus core protein enhances NF-κB signal pathway triggering by lymphotoxin β receptor ligand and TNFα. J Virol 1999;73:1672-81.
22. Harada K, Tsuneyama K, Hiramatsu K, et al. Significance of CD30-positive lymphocytes in livers in primary biliary cirrhosis. J Gastroenterol Hepatol 1999;14:1197-202.
23. Tilg H, Diehl AM. Cytokines in alcoholic and non-alcoholic steatohepatitis. N Engl J Med 2000;343:1467-76.
24. Hayashi N, Mita E. Involvement of Fas system-mediated apoptosis in pathogenesis of viral hepatitis. J Viral Hepatol 1999;6:357-65.
25. Neuman M, Angulo P, Malkiewicz I, et al. Tumour necrosis factor-alpha and transforming growth factor-beta reflect severity of liver damage in primary biliary cirrhosis. J Gastroenterol Hepatol 2002;17:196-202.
26. Chen C, You L, Hwang L, et al. Direct interaction of hepatitis C virus core protein with the cellular lymphotoxin β receptor modulates the signal pathway of the lymphotoxin β receptor. J Virol 1997;71:9417-26.
27. Brunt EM. Grading and staging the histopathological lesions of chronic hepatitis: the Knodell histology activity index and beyond. Hepatology 2000;31:241-6.
28. Akerman PA, Cote P, Yang SQ. Antibodies to tumour necrosis factor α inhibit liver regeneration after partial hepatectomy. Am J Physiol 1992;263:G579-85.
29. Yamada Y, Kirillova I, Peschon JJ, et al. Initiation of liver growth by tumour necrosis factor: deficient liver regeneration in mice lacing type tumour necrosis factor receptor. Proc Natl Acad Sci U S A 1997;94:1441-9.
30. Ware CF, Crowe PD, Grayson MH, et al. Expression of surface lymphotoxin and tumor necrosis factor on activated T, B, and natural killer cells. J Immunol 1992;149:3881-8.
31. Lolor PF, Shields P, Grant A, et al. Recruitment of lymphocytes to the human liver. Immunol Cell Biol 2002;80:52-64.
32. Kuprash DV, Alimzhanov MB, Tumanov AV, et al. TNF and lymphotoxin β co- operate in the maintenance of secondary lymphoid tissue microarchitecture but not in the development of lymph nodes. J Immunol 1999;163:6575-80.
33. Adams DH, Hubscher S, Fear J, et al. Hepatic expression of macrophage inflammatory protein-1 alpha and macrophage inflammatory protein-1 beta after liver transplantation. Transplantation 1996;61:817-25.
34. Afford SC, Fisher NC, Neil DA, et al. Distinct patterns of chemokine expression are associated with leukocyte recruitment in alcoholic hepatitis and alcoholic cirrhosis. J Pathol 1998;186:82-9.
35. Shields PL, Morland CM, Salmon M, et al. Chemokine and chemokine receptor interactions provide a mechanism for selective T cell recruitment to specific liver compartments within hepatitis C-infected liver. J Immunol 1999;163:6236-43.
36. Petersen BE, Bowen WC, Patrene KD, et al. Bone marrow as a potential source of hepatic oval cells. Science 1999;14:1168-70.
37. Alison MR, Poulsom R, Jeffery R, et al. Hepatocytes from non-hepatic stem cells. Nature 2000;406:257.
38. Thiese ND, Nimmakayalu M, Gardner R, et al. Liver from bone marrow in humans. Hepatology 2000;32:11-16.
39. Lagasse E, Connors H, Al-Dhalimy M, et al. Purified hematopoietic stem cells can differentiate into hepatocytes in vitro. Nat Med 2000;6:1229-34.