Familial aggregation of psychotic symptoms in a replication set of 69 bipolar disorder pedigrees

American Journal of Medical Genetics - Neuropsychiatric Genetics

Volumn 116 B, Issue 1, 2003, Pages 90-97

  Potash, James B ^a,e   Chiu, Yen Feng ^b   MacKinnon, Dean F ^a   Miller, Erin B ^a   Simpson, Sylvia G ^c   McMahon, Francis J ^d   McInnis, Melvin G ^a   DePaulo Jr , J Raymond ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b IL   (United States)

^c UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^d NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^e JOHNS HOPKINS HOSPITAL   (United States)

Author keywords

Bipolar disorder; Family study; Genetics; Heterogeneity; Psychosis; Schizophrenia; Subtype

Indexed keywords

BIOLOGICAL MARKER;

ADULT; ARTICLE; BIPOLAR DISORDER; CLUSTER ANALYSIS; CONTROLLED STUDY; DELUSION; FAMILIAL DISEASE; GENETIC SUSCEPTIBILITY; HALLUCINATION; HUMAN; LINKAGE ANALYSIS; MAJOR CLINICAL STUDY; MOOD DISORDER; NEUROPATHOLOGY; PATHOPHYSIOLOGY; PEDIGREE; PRIORITY JOURNAL; PSYCHOSIS; RELATIVE; SCHIZOPHRENIA; VALIDATION PROCESS;

EID: 0042878491     PISSN: 15524841     EISSN: 1552485X     Source Type: Journal    
DOI: 10.1002/ajmg.b.10761     Document Type: Article

References (38)

1. Berrettini WH. 2000. Are schizophrenic and bipolar disorders related? A review of family and molecular studies. Biol Psychiatry 48:531-538.
2. Black DW, Nasrallah A. 1989. Hallucinations and delusions in 1,715 patients with unipolar and bipolar affective disorders. Psychopathology 22:28-34.
3. Coryell W. 1997. Do psychotic, minor and intermittent depressive disorders exist on a continuum? J Affect Disord 45:75-83.
4. DeLisi LE, Goldin LR, Maxwell ME, Kazuba DM, Gershon ES. 1987. Clinical features of illness in siblings with schizophrenia or schizoaffective disorder. Arch Gen Psychiatry 44:891-896.
5. Endicott J, Spitzer RL. 1978. A diagnostic interview: the schedule for affective disorders and schizophrenia. Arch Gen Psychiatry 35:837-844.
6. Erlenmeyer-Kimling L, Adamo UH, Rock D, Roberts SA, Bassett AS, Squires-Wheeler E, Cornblatt BA, Endicott J, Pape S, Gottesman II. 1997. The New York High-Risk Project. Prevalence and comorbidity of axis I disorders in offspring of schizophrenic parents at 25-year follow-up. Arch Gen Psychiatry 54:1096-1102.
7. Freedman R, Coon H, Myles-Worsley M, Orr-Urtreger A, Olincy A, Davis A, Polymeropoulos M, Holik J, Hopkins J, Hoff M, Rosenthal J, Waldo MC, Reimherr F, Wender P, Yaw J, Young DA, Breese CR, Adams C, Patterson D, Adler LE, Kruglyak L, Leonard S, Byerley W. 1997. Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus. Proc Natl Acad Sci USA 94:587-592.
8. Gershon ES, Hamovit J, Guroff JJ, Dibble E, Leckman JF, Sceery W, Targum SD, Nurnberger JIJ, Goldin LR, Bunney WEJ. 1982. A family study of schizoaffective, bipolar I, bipolar II, unipolar, and normal control probands. Arch Gen Psychiatry 39:1157-1167.
9. Gershon ES, DeLisi LE, Hamovit J, Nurnberger JIJ, Maxwell ME, Schreiber J, Dauphinais D, Dingman CW, Guroff JJ. 1988. A controlled family study of chronic psychoses. Schizophrenia and schizoaffective disorder. Arch Gen Psychiatry 45:328-336.
10. Gilvarry CM, Russell A, Hemsley D, Murray RM. 2001. Neuropsychological performance and spectrum personality traits in the relatives of patients with schizophrenia and affective psychosis. Psychiatry Res 101:89-100.
11. Goldstein RB, Horwath E, Wickramaratne PJ, Wolk SI, Warner V, Weissman MM. 1998. Familial aggregation of delusional depression: re-examination in a recent family study. Depress Anxiety 8:160-165
12. Goodwin FK, Jamison KR. 1990. Manic-depressive illness. New York: Oxford University Press. p 35.
13. Guidotti A, Auta J, Davis JM, Gerevini VD, Dwivedi Y, Grayson DR, Impagnatiello F, Pandey G, Pesold C, Sharma R, Uzunov D, Costa E. 2000. Decrease in reelin and glutamic acid decarboxylase67 (GAD67) expression in schizophrenia and bipolar disorder: a postmortem brain study. Arch Gen Psychiatry 57:1061-1069.
14. Hirayasu Y, Shenton ME, Salisbury DF, Dickey CC, Fischer IA, Mazzoni P, Kisler T, Arakaki H, Kwon JS, Anderson JE, Yurgelun-Todd D, Tohen M, McCarley RW. 1998. Lower left temporal lobe MRI volumes in patients with first-episode schizophrenia compared with psychotic patients with first-episode affective disorder and normal subjects. Am J Psychiatry 155:1384-1391.
15. Johnson J, Horwath E, Weissman MM. 1991. The validity of major depression with psychotic features based on a community study. Arch Gen Psychiatry 48:1075-1081.
16. Kendler KS, Gruenberg AM, Tsuang MT. 1985. Psychiatric illness in first-degree relatives of schizophrenic and surgical control patients. A family study using DSM-III criteria. Arch Gen Psychiatry 42:770-779.
17. Kendler KS, Gruenberg AM, Tsuang MT. 1986. A DSM-III family study of the nonschizophrenic psychotic disorders. Am J Psychiatry 143:1098-1105.
18. Kendler KS, McGuire M, Gruenberg AM, O'Hare A, Spellman M, Walsh D. 1993a. The Roscommon Family Study. I. Methods, diagnosis of probands, and risk of schizophrenia in relatives. Arch Gen Psychiatry 50:527-540.
19. Kendler KS, McGuire M, Gruenberg AM, O'Hare A, Spellman M, Walsh D. 1993b. The Roscommon Family Study. IV. Affective illness, anxiety disorders, and alcoholism in relatives. Arch Gen Psychiatry 50:952-960.
20. Kendler KS, Karkowski-Shuman L, O'Neill FA, Straub RE, MacLean CJ, Walsh D. 1997. Resemblance of psychotic symptoms and syndromes in affected sibling pairs from the Irish Study of High-Density Schizophrenia Families: evidence for possible etiologic heterogeneity. Am J Psychiatry 154:191-198.
21. Leckman JF, Weissman MM, Prusoff BA, Caruso KA, Merikangas KR, Pauls DL, Kidd KK. 1984. Subtypes of depression. Family study perspective. Arch Gen Psychiatry 41:833-838.
22. Liang KY, Zeger SL. 1986. Longitudinal data analysis using generalized linear models. Biometrika 73:13-22.
23. Luria RE, McHugh PR. 1974. Reliability and clinical utility of the "Wing" Present State examination. Arch Gen Psychiatry 30:866-871.
24. Maier W, Lichtermann D, Minges J, Hallmayer J, Heun R, Benkert O, Levinson DF. 1993. Continuity and discontinuity of affective disorders and schizophrenia. Results of a controlled family study. Arch Gen Psychiatry 50:871-883.
25. NIMH Genetics Initiative Bipolar Group. 1997. Genomic survey of bipolar illness in the NIMH genetics initiative pedigrees: a preliminary report. Am J Med Genet 74:227-237.
26. Nurnberger JIJ, Blehar MC, Kaufmann CA, York-Cooler C, Simpson SG, Harkavy-Friedman J, Severe JB, Malaspina D, Reich T. 1994. Diagnostic interview for genetic studies. Rationale, unique features, and training. NIMH Genetics Initiative. Arch Gen Psychiatry 51:849-859.
27. 2 dopamine receptor density in psychotic and nonpsychotic patients with bipolar disorder. Arch Gen Psychiatry 52:471-477.
28. Potash JB, Willour VL, Chiu Y-F, Simpson SG, MacKinnon DF, Pearlson GD, DePaulo JR Jr, McInnis MG. 2001. The familial aggregation of psychotic symptoms in bipolar disorder pedigrees. Am J Psychiatry 158:1258-1264.
29. Pulver AE, Mulle J, Nestadt G, Swartz KL, Blouin J-L, Dombroski B, Liang K-Y, Housman DE, Kazazian HH, Antonarakis SE, Lasseter VK, Wolyniec PS, Thornquist MH, McGrath JA. 2000. Genetic heterogeneity in schizophrenia: stratification of genome scan data using co-segregating related phenotypes. Mol Psychiatry 5:650-653.
30. Roy MA, Lanctot G, Merette C, Cliche D, Fournier JP, Boutin P, Rodrigue C, Charron L, Turgeon M, Hamel M, Montgrain N, Nicole L, Pires A, Wallot H, Ponton AM, Garneau Y, Dion C, Lavallee JC, Potvin A, Szatmari P, Maziade M. 1997. Clinical and methodological factors related to reliability of the best-estimate diagnostic procedure. Am J Psychiatry 154:1726-1733.
31. Siris SG, Rifkin A, Reardon GT, Endicott J, Pereira DH, Hayes R, Casey E. 1984. Course-related depressive syndromes in schizophrenia. Am J Psychiatry 141:1254-1257.
32. Spitzer RL, Fleiss JL, Burdock EI, Hardesty AS. 1964. The mental status schedule: rationale, reliability and validity. Compr Psychiatry 5:384-395.
33. Tarone RE. 1979. Testing the goodness-of-fit of the binomial distribution. Biometrika 66:585-590.
34. Velakoulis D, Pantelis C, McGorry PD, Dudgeon P, Brewer W, Cook M, Desmond P, Bridle N, Tierney P, Murrie V, Singh B, Copolov D. 1999. Hippocampal volume in first-episode psychoses and chronic schizophrenia: a high-resolution magnetic resonance imaging study. Arch Gen Psychiatry 56:133-141.
35. Wassink TH, Flaum M, Nopoulos P, Andreasen NC. 1999. Prevalence of depressive symptoms early in the course of schizophrenia. Am J Psychiatry 156:315-316.
36. Wickham H, Walsh C, Asherson P, Taylor C, Sigmundson T, Gill M, Owen MJ, McGuffin P, Murray R, Sham P. 2001. Familiality of symptom dimensions in schizophrenia. Schizophr Res 47:223-232.
37. Wing JK, Birley JL, Cooper JE, Graham P, Isaacs AD. 1967. Reliability of a procedure for measuring and classifying "present psychiatric state. " Br J Psychiatry 113:499-515.
38. Winokur G, Scharfetter C, Angst J. 1985. A family study of psychotic symptomatology in schizophrenia, schizoaffective disorder, unipolar depression, and bipolar disorder. Eur Arch Psychiatry Neurol Sci 234:295-298.