Interaction of leptin with gastric myofibroblast transdifferentiation in Helicobacter pylori-infected Mongolian gerbils: The effect of rebamipide

Alimentary Pharmacology and Therapeutics, Supplement

Volumn 18, Issue 1, 2003, Pages 99-105

  Nakamura, M ^a   Akiba, Y ^b   Matsui, H ^c   Tsuchimoto, K ^d   Ishii, H ^b  

^a KITASATO INSTITUTE   (Japan)

^b KEIO UNIVERSITY   (Japan)

^c KITASATO UNIVERSITY   (Japan)

^d KITASATO INSTITUTE HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

LEPTIN; REBAMIPIDE; TRITIUM; ALANINE; ANTIULCER AGENT; DRUG DERIVATIVE; QUINOLONE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; AUTORADIOGRAPHY; CELL DIFFERENTIATION; CONFERENCE PAPER; CONTROLLED STUDY; DRUG BINDING SITE; DRUG EFFECT; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; FIBROBLAST; GERBIL; HELICOBACTER INFECTION; HELICOBACTER PYLORI; IMMUNOFLUORESCENCE; IMMUNOREACTIVITY; ISOTOPE LABELING; MESENCHYME; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN LOCALIZATION; STOMACH FUNDUS; STOMACH MUCOSA; ANIMAL; ARTICLE; BLOOD; IMMUNOHISTOCHEMISTRY; PATHOLOGY; PHYSIOLOGY;

ALANINE; ANIMALS; ANTI-ULCER AGENTS; AUTORADIOGRAPHY; CELL DIFFERENTIATION; FIBROBLASTS; GERBILLINAE; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; IMMUNOHISTOCHEMISTRY; LEPTIN; QUINOLONES;

EID: 0042849080     PISSN: 09530673     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2036.18.s1.11.x     Document Type: Conference Paper

References (14)

1. Nakamura M, Oda M, Inoue J, Ito T, Akiba Y, Kitajima M. Plasticity of myofibroblasts appearing in granulation tissues after acetic acid treatment effect of bFGF. Dig Dis Sci 1995; 40: 2477-80.
2. Nakamura M, Akiba Y, Oda M, Ishii H. Alteration of basic fibroblast growth factor concentration and immunoreactivity in healing of ethanol-induced gastric mucosal damage: effect of sofalcone. J Clin Gastroenterol 1997: 25(Suppl. 1): S13-S20.
3. Mallat A, Fouassier L, Preaux AM, Gal CS, Raufaste D. Growth inhibitory properties of endothelin-1 in human hepatic myofibroblastic Ito cells. An endothelin B receptor-mediated pathway. J Clin Invest 1995; 96(1): 42-9.
4. Glasow AKW, Anderegg U, Berthold A, Bottner A, Kratzsch J. Expression of leptin (Ob) and leptin receptor (Ob-R) in human fibroblasts: regulation of leptin secretion by insulin. J Clin Endocrinol Metab 2001; 86(9): 4472-9.
5. Hosoda K, Masuzaki H, Ogawa Y, et al. Development of radioimmunoassay for human leptin. Biochem Biophys Res Commun 1996; 221(2): 234-9.
6. Nakamura M, Oda M, Akiba Y, et al. Autoradiographic demonstration of lansoprazole uptake sites in rat antrum and colon. J Clin Gastroenterol 1995; 20(Suppl. 2): S8-S13.
7. Nagata T, Nawa T, Yokota S, et al. A new technique for electron microscopic dry-mounting radioautography of soluble compounds. Histochemie 1969; 18: 241-9.
8. Breidert M, Miehike S, Glasow A, et al. Leptin and its receptor in normal human gastric mucosa and Helicobacter pylori-associated gastritis. Scand J Gastroenterol 1999; 34: 954-61.
9. Azuma T, Suto Y, Ito M, et al. Gastric leptin and Helicobacter pylori infection. Gut 2001; 49: 324-9.
10. Bado ALS, Attoub S, Kermorgant S, et al. The stomach is a source of leptin. Nature 1998; 394(6695): 790-3.
11. Konturek PC, Brzozowski T, Sulekova Z, et al. Role of leptin in ulcer healing. Eur J Phamacol 2001; 414: 87-97.
12. Cao RBE, Wahlestedt C, Thyberg J, Cao Y. Leptin induces vascular permeability and synergistically stimulates angiogenesis with FGF-2 and VEGF. Proc Natl Acad Sci USA 2000; 98(11): 6390-5.
13. Cohen BBD, Levy Y, Goldberg I, Fridman E, Kopolovic J, Rubinstein M. Leptin induces angiopoietin-2 expression in adipose tissues. J Biol Chem; 2001; 276(11): 7697-700.
14. Yoshikawa T, Naito Y, Nakamura S, et al. Effect of rebamipide on lipid peroxidation and gastric mucosal injury induced by indomethacin in rats. Arzneim-Forsch/Drug Res 1993; 43: 1327-30.