Plasma endothelin-1 levels in patients with biliary atresia: Possible role in development of portal hypertension

Pediatric Surgery International

Volumn 19, Issue 6, 2003, Pages 478-481

  Chongsrisawat, V ^a   Chatchatee, P ^a   Samransamruajkit, R ^a   Vanapongtipagorn, P ^a   Chottivittayatarakorn, P ^a   Poovorawan, Y ^a  

^a CHULALONGKORN UNIVERSITY   (Thailand)

Author keywords

Biliary atresia; Endothelin 1; Portal hypertension

Indexed keywords

AMINOTRANSFERASE; ENDOTHELIN 1;

ARTICLE; BILE DUCT ATRESIA; CHILD; CLINICAL ARTICLE; COLLAGEN SYNTHESIS; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; INFLAMMATION; JAUNDICE; LIVER FIBROSIS; MALE; PATHOGENESIS; PORTAL HYPERTENSION; PORTOENTEROSTOMY; PRIORITY JOURNAL;

BILIARY ATRESIA; CHILD; CHILD, PRESCHOOL; DISEASE PROGRESSION; ENDOTHELIN-1; FEMALE; FIBROSIS; HUMANS; HYPERTENSION, PORTAL; INFANT; MALE;

EID: 0042839615     PISSN: 01790358     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00383-003-0963-z     Document Type: Article

References (31)

1. Ramm GA, Nair VG, Bridle KR, Shepherd RW, Crawford DH (1998) Contribution of hepatic parenchymal and nonparenchymal cells to hepatic fibrogenesis in biliary atresia. Am J Pathol 153:527-535
2. Rubanyi GM (1991) Endothelium-derived relaxing and contracting factors. J Cell Biochem 46:27-36
3. Rubanyi GM, Botelho LH (1991) Endothelins. Faseb J 5:2713-2720
4. Boulanger CM (1999) Secondary endothelial dysfunction: hypertension and heart failure. J Mol Cell Cardiol 31:39-49
5. Malek AM, Zhang J, Jiang J, Alper SL, Izumo S (1999) Endothelin-1 gene suppression by shear stress: pharmacological evaluation of the role of tyrosine kinase, intracellular calcium, cytoskeleton, and mechanosensitive channels. J Mol Cell Cardiol 31:387-399
6. Williams B (1998) Mechanical influences on vascular smooth muscle cell function. J Hypertens 16:1921-1929
7. Takahashi M, Ishida T, Traub O, Corson MA, Berk BC (1997) Mechanotransduction in endothelial cells: temporal signaling events in response to shear stress. J Vasc Res 34:212-219
8. Stoltz JF, Boisseau M, Muller S, Wang X, Legrand S, Labrador MV (1999) Hemorheology and vascular endothelial cells. J Mal Vasc 24:99-109
9. Inoue A, Yanagisawa M, Kimura S, et al (1989) The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes. Proc Natl Acad Sci 86:2863-2867
10. Levin ER (1996) Endothelins as cardiovascular peptides. Am J Nephrol 16:246-251
11. Moller S, Gulberg V, Henriksen JH, Gerbes AL (1995) Endothelin-1 and endothelin-3 in cirrhosis: relations to systemic and splanchnic haemodynamics. J Hepatol 23:135-144
12. Stojilkovic SS, Catt KJ (1992) Neuroendocrine actions of endothelins. Trends Pharmacol Sci 13:385-391
13. Yanagisawa M, Kurihara H, Kimura S, et al (1988) A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 332:411-415
14. Yanagisawa M (1994) The endothelin system. A new target for therapeutic intervention. Circulation 89:1320-1322
15. Rockey DC, Fouassier L, Chung JJ, et al (1998) Cellular localization of endothelin-1 and increased production in liver injury in the rat: potential for autocrine and paracrine effects on stellate cells. Hepatology 27:472-480
16. Cahill PA, Redmond EM, Sitzmann JV (2001) Endothelial dysfunction in cirrhosis and portal hypertension. Pharmacol Ther 89:273-293
17. Sogni P, Moreau R, Gadano A, Lebrec D (1995) The role of nitric oxide in the hyperdynamic circulatory syndrome associated with portal hypertension. J Hepatol 23:218-224
18. Haynes WG, Webb DJ (1994) Contribution of endogenous generation of endothelin-1 to basal vascular tone. Lancet 344:852-854
19. Martin PY, Xu DL, Niederberger M, et al (1996) Upregulation of endothelial constitutive NOS: a major role in the increased NO production in cirrhotic rats. Am J Physiol 270:F494-499
20. Rubanyi GM, Polokoff MA (1994) Endothelins: molecular biology, biochemistry, pharmacology, physiology, and pathophysiology. Pharmacol Rev 46:325-415
21. Leivas A, Jimenez W, Lamas S, et al (1995) Endothelin 1 does not play a major role in the homeostasis of arterial pressure in cirrhotic rats with ascites. Gastroenterology 108:1842-1848
22. Iwasaki T, Notoya M, Hayasaki-Kajiwara Y, et al (1999) Endothelium-independent vascular relaxation mediating ETB receptor in rabbit mesenteric arteries. Am J Physiol 276:H383-390
23. Sogni P, Moreau R, Gomola A, et al (1998) Beneficial hemodynamic effects of bosentan, a mixed ET(A) and ET(B) receptor antagonist, in portal hypertensive rats. Hepatology 28:655-659
24. Reichen J, Gerbes AL, Steiner MJ, Sagesser H, Clozel M (1998) The effect of endothelin and its antagonist Bosentan on hemodynamics and microvascular exchange in cirrhotic rat liver. J Hepatol 28:1020-1030
25. Cho JJ, Hocher B, Herbst H, et al (2000) An oral endothelin-A receptor antagonist blocks collagen synthesis and deposition in advanced rat liver fibrosis. Gastroenterology 118:1169-1178
26. Asbert M, Gines A, Gines P, et al (1993) Circulating levels of endothelin in cirrhosis. Gastroenterology 104:1485-1491
27. Hartleb M, Kirstetter P, Moreau R, et al (1994) Relationships between plasma concentrations of endothelin and the severity of liver cirrhosis. Gastroenterol Clin Biol 18:407-412
28. Kobayashi H, Miyano T, Horikoshi K, Orihata K, Watanabe S, Futagawa S (1998) Clinical significance of plasma endothelin levels in patients with biliary atresia. Pediatr Surg Int 13:491-493
29. Kamath PS, Carpenter HA, Lloyd RV, et al (2000) Hepatic localization of endothelin-1 in patients with idiopathic portal hypertension and cirrhosis of the liver. Liver Transpl 6:596-602
30. Matsumoto H, Uemasu J, Kitano M, Kawasaki H (1994) Clinical significance of plasma endothelin-1 in patients with chronic liver disease. Dig Dis Sci 39:2665-2670
31. Uchida Y, Watanabe M (1993) Plasma endothelin-1 concentrations are elevated in acute hepatitis and liver cirrhosis but not in chronic hepatitis. Gastroenterol Jpn 28:666-672