African Americans with LVH demonstrate depressed sensitivity of the coronary microcirculation to stimulated relaxation

Hypertension

Volumn 42, Issue 3, 2003, Pages 269-276

  Houghton, Jan Laws ^a   Strogatz, David S ^b   Torosoff, Mikhail T ^a   Smith, Vivienne E ^a   Fein, Steven A ^a   Kuhner, Patricia A ^a   Philbin, Edward F ^a   Carr, Albert A ^c  

^a ALBANY MEDICAL COLLEGE   (United States)

^b STATE UNIVERSITY OF NEW YORK   (United States)

^c Circulatory Disease Center   (United States)

Author keywords

Endothelium; Ethnicity; Hypertension, chronic; Hypertrophy; Left ventricular; Microcirculation; Vasodilation

Indexed keywords

ACETYLCHOLINE;

ADULT; ARTICLE; BLOOD VESSEL DIAMETER; BLOOD VESSEL REACTIVITY; BODY MASS; CAUCASIAN; CHOLINERGIC ACTIVITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORONARY ARTERY; CORONARY ARTERY BLOOD FLOW; DRUG SENSITIVITY; FEMALE; HEART LEFT VENTRICLE HYPERTROPHY; HEART LEFT VENTRICLE MASS; HEART MUSCLE RELAXATION; HEART RATE VARIABILITY; HEMODYNAMICS; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; MEAN ARTERIAL PRESSURE; MICROCIRCULATION; MORBIDITY; NEGRO; PATHOPHYSIOLOGY; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; RACE DIFFERENCE;

ACETYLCHOLINE; ADULT; AFRICAN AMERICANS; ANALYSIS OF VARIANCE; CORONARY CIRCULATION; ECHOCARDIOGRAPHY; ENDOTHELIUM, VASCULAR; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; HUMANS; HYPERTENSION; HYPERTROPHY, LEFT VENTRICULAR; MALE; MIDDLE AGED; MYOCARDIAL ISCHEMIA; SOCIAL CLASS; VASCULAR RESISTANCE; VASODILATION;

EID: 0042835364     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.0000087840.43329.01     Document Type: Article

References (53)

1. Gillum RF. Coronary heart disease in black populations. I. Mortality and morbidity. Am Heart J. 1982;104:839-851.
2. Sempos C, Cooper R, Kovar M, McMillen M. Divergence of the recent trends in coronary mortality for the four major race-sex groups in the United States. Am J Public Health. 1988;78:422-427.
3. Gillum RF, Mussolino ME, Madans JH. CHD incidence and survival in African American women and men: the NHANES-I epidemiologic follow-up study. Ann Intern Med. 1997;127:111-118.
4. Williams JE, Massing M, Rosamond WD, Sorlie PD, Tyroler HA. Racial disparities in CHD mortality from 1968-1992 in the state economic areas surrounding the ARIC study communities. Ann Epidemiol. 1999;9: 472-480.
5. Alderman MH, Cohen HW, Madhavan S. Myocardial infarction in treated hypertensive patients: the paradox of lower incidence but higher mortality in young blacks compared with whites. Circulation. 2000;101: 1109-1114.
6. Wilson PW. An epidemiologic perspective of systemic hypertension, ischemic heart disease, and heart failure. Am J Cardiol. 1997;80:3J-8J.
7. Dries DL, Exner DV, Gersh BJ, Cooper HA, Carson PE, Domanski M. Racial differences in the outcome of left ventricular dysfunction. N Engl J Med. 1999;340:609-616.
8. Coughlin SS, Neaton JD, Sengupta X, Kuller LH. Predictors of mortality from idiopathic dilated cardiomyopathy study: 356,222 men screened for the MRFIT. Am J Epidemiol. 1994;139:166-172.
9. Gardin JM, Wagenknecht LE, Anton-Culver H, Flack J, Gidding S, Kurosaki T, Wong ND, Manolio TA. Relationship of cardiovascular risk factors to echocardiographic ventricular mass in healthy young black and white adult men and women: the CARDIA Study: Coronary Artery Risk Development in Young Adults. Circulation. 1995;92:380-387.
10. Califf RM, Pieper KS, Lee KL, VanDeWerf F, Simes RJ, Armstrong PW, Topol EJ. Prediction of 1-year survival after thrombolysis for acute MI in the global utilization of streptokinase and t-PA for occluded coronary arteries trial. Circulation. 2000;101:2231-2238.
11. Scirica BM, Moliterno DJ, Every NR, Anderson HV, Aguirre FV, Granger CB, Lambrew CT, Rabbani LE, Sapp SK, Booth JE, Ferguson JJ, Cannon CP. Racial differences in the management of unstable angina: results from the multicenter GUARANTEE registry. Am Heart J. 1999; 138:1065-1072.
12. Freedman DS, Gruchow H, Manley JC, Anderson AJ, Sobocinski KA, Barboriak JJ. Black/white differences in risk factors for arteriographically documented CAD in men. Am J Cardiol. 1988;62:214-219.
13. Stone PH, Thompson B, Anderson HV, Kronenberg MW, Gibson RS, Rogers WJ, Diver DJ, Theroux P, Wamica JW, Nasmith JB, Kells C, Kleiman N, McCabe CH, Schactman M, Knatterud GL, Braunwald E. Influence of race, sex, and age on management of unstable angina and non-Q-wave MI: the TIMI registry. JAMA. 1996;275:1104-1112.
14. Chen J, Rathore SS, Radford MJ, Wang Y, Krumholz HM. Racial differences in the use of cardiac catheterization after acute MI. N Engl J Med. 2001;344:1471-1473.
15. Howard G, Anderson RT, Russell G, Howard VJ, Burke GL. Race, socioeconomic status, and cause-specific mortality. Ann Epidemiol 2000; 10:214-223.
16. Longhurst PA, Rice PJ, Taylor DA, Fleming WW. Sensitivity of caudal arteries and the mesenteric vascular bed to norepinephrine in DOCA-salt hypertension. Hypertension. 1988;12:133-142.
17. Webb RC. Increased vascular sensitivity to serotonin and methysergide in hypertension in rats. Clin Sci. 1982;63:73S-75S.
18. Lockette W, Otsuka Y, Carretero O. The loss of endothelium-dependent vascular relaxation in hypertension. Hypertension. 1986;8(suppl II):II-61-II-66.
19. Houghton JL, Smith VE, Strogatz DS, Henches NL, Breisblatt WM, Carr AA. Effect of African American race and hypertensive LVH on coronary vascular reactivity and endothelial function. Hypertension. 1997;29: 706-714.
20. DeSimone G, Devereux RB, Daniels SR, Koren MJ, Meyer RA, Laragh JH. Effect of growth on variability of left ventricular mass: assessment of allometric signals in adults and children and their capacity to predict cardiovascular risk. J Am Coll Cardiol. 1995;25:1056-1062.
21. Devereux RB, Reichek N. Echocardiographic determination of LV mass in man: anatomic validation of the method. Circulation. 1977;55: 613-618.
22. Houghton JL, Davison CA, Kuhner PA, Torossov MT, Strogatz DS, Carr AA. Heterogeneous vasomotor responses of coronary conduit and resistance vessels in hypertension. J Am Coll Cardiol. 1998;31:374-382.
23. Reddy KG, Nair RN, Sheehan HM, Hodgson JM. Evidence that selective endothelial dysfunction may occur in the absence of angiographic or ultrasound atherosclerosis in patients with risk factors for atherosclerosis. J Am Coll Cardiol. 1994;23:833-843.
24. Houghton JL, Frank MJ, Carr A, von Dohlen TW, Prisant LM. Relations among impaired coronary flow reserve, left ventricular hypertrophy, and thallium perfusion defects in hypertensive patients without obstructive coronary artery disease. J Am Coll Cardiol. 1990;5:43-51.
25. Smith RH, LePetri B, Moisa RB, Studzinski M, Flaster E, Steingart RM. Association of increased left ventricular mass in the absence of electrocardiographic LVH with ST depression during exercise. Am J Cardiol. 1995;76:973-974.
26. Fragasso G, Lu C, Dabrowski P, Pagnotta P, Sheiban I, Chierchia SL. Comparison of stress/rest myocardial perfusion tomography, dipyridamole and dobutamine stress echocardiography for the detection of coronary disease in hypertensive patients with chest pain and positive exercise tests. J Am Coll Cardiol. 1999;34:441-447.
27. Zeiher AM, Krause T, Schachinger V, Minners J, Moser E. Impaired endothelium-dependent vasodilation of coronary resistance vessels is associated with exercise-induced myocardial ischemia. Circulation. 1995; 91:2345-2352.
28. Chilian WM. Coronary microcirculation in health and disease: summary of an NHLBI workshop. Circulation. 1997;95:522-528.
29. Quillen JE, Rossen JD, Oskarsson HJ, Minor RL, Lopez AG, Winniford MD. Acute effect of cigarette smoking on the coronary circulation: constriction of epicardial and resistance vessels. J Am Coll Cardiol. 1993;22:642-647.
30. Gordon JB, Ganz P, Nabel EG, Fish RD, Zebede J, Mudge GH, Alexander RW, Selwyn AP. Atherosclerosis influences the vasomotor response of epicardial coronary arteries to exercise. J Clin Invest. 1989; 83:1946-1952.
31. Vita JA, Treasure CB, Yeung AC, Vekshtein VI, Fantasia GM, Fish RD, Ganz P, Selwyn AP. Patients with evidence of coronary endothelial dysfunction as assessed by acetylcholine infusion demonstrate marked increase in sensitivity to constrictor effects of catecholamines. Circulation. 1992;85:1390-1397.
32. Luscher T, Boulanger CM, Dohi Y, Yang ZH. Endothelium-derived contracting factors. Hypertension. 1992;19:117-130.
33. Weinberger MH. Salt sensitivity of blood pressure in humans. Hypertension. 1996;27:481-490.
34. Lorber R, Gidding SS, Daviglus ML, Colangelo LA, Liu K, Gardin JM. Influence of systolic blood pressure and body mass index on left ventricular structure in healthy African American and white young adults: the CARDIA study. J Am Coll Cardiol. 2003;41:955-960.
35. East MA, Jollis JG, Nelson CL, Marks D, Peterson ED. The influence of left ventricular hypertrophy on survival in patients with coronary artery disease: do race and gender matter? J Am Coll Cardiol. 2003;41: 949-954.
36. Aviv A. Salt and hypertension. Arch Intern Med. 2001;161:507-510.
37. Coca A, DelaSierra A. Salt sensitivity and left ventricular hypertrophy. Adv Exp Med Biol. 1997;432:91-101.
38. Hayakawa H, Coffee K, Raij L. Endothelial dysfunction and cardiorenal injury in experimental salt sensitive hypertension. Circulation. 1997;96: 2407-2413.
39. Schiffrin EL. Role of endothelin-1 in hypertension and vascular disease. Am J Hypertens. 2001;14:83S-89S.
40. Rothermund L, Vetter R, Dieterich M, Kossmehl P, Gogebakan O, Yagil C, Yagil Y, Kreutz R. Endothelin-A receptor blockade prevents left ventricular hypertrophy and dysfunction in salt-sensitive experimental hypertension. Circulation. 2002;106:2305-2308.
41. Ergul A. Hypertension in black patients: an emerging role of the endothelin system in salt-sensitive hypertension. Hypertension. 2000;36: 62-67.
42. Yang Z, Richard V, von Segesser L, Bauer E, Stultz P, Turina M, Luscher TF. Threshold concentrations of endothelin-1 potentiates contractions to norepinephrine and serotonin in human arteries. Circulation. 1990;82: 182-195.
43. Fujiwara N, Osanai T, Kamada T, Katoh T, Takahashi K, Okumura K. Study of the relationship between plasma nitrite and nitrate levels and salt sensitivity in human hypertension. Circulation. 2000;101:856-861.
44. Murphy JK, Alpert BS, Moes DM, Somes GW. Race and cardiovascular reactivity: a neglected relationship. Hypertension. 1986;8:1075-1083.
45. Saab PG, Llabre MM, Hurwitz BE, Frame CA, Reineke LJ, Fins AI, McCalla J, Cieply LK, Schneiderman N. Myocardial and peripheral vascular responses to behavioral challenges and their stability in black and white Americans. Psychophysiology. 1992;29:384-397.
46. Light KC, Turner JR, Hinderliter AL, Sherwood A. Race and gender comparisons, I: hemodynamic responses to a series of stressors. Health Psychol. 1993;12:354-365.
47. Hinderliter AL, Sager AR, Sherwood A, Light KC, Girdler SS, Willis PW. Ethnic differences in forearm vasodilator capacity. Am J Cardiol. 1996;78:208-211.
48. Lang CC, Stein CM, Brown RM, Deegan R, Nelson R, He HB, Wood M, Wood AJ. Attenuation of isoproterenol-mediated vasodilation in blacks. N Engl J Med. 1995;333:155-160.
49. Cardillo C, Kilcoyne CM, Cannon III RO, Panza JA. Attenuation of cyclic nucleotide-mediated smooth muscle relaxation in blacks as a cause of racial differences in vasodilator function. Circulation. 1999;99:90-95.
50. Perragaux D, Chaudhuri A, Rao S, Airen A, Wilson M, Sung BH, Dand P. Brachial vascular reactivity in blacks. Hypertension. 2000;36: 866-876.
51. Jones DS, Andrawis NS, Abernethy DR. Impaired endothelial-dependent forearm vascular relaxation in black Americans. Clin Pharmacol Ther. 1999;65:408-412.
52. Suwaidi JA, Hamasaki S, Higano ST, Nishimura RA, Holmes DR, Lerman A. Long-term follow-up of patients with mild coronary artery disease and endothelial dysfunction. Circulation. 2000;101:948-954.
53. Schachinger V, Britten MB, Zeiher AM. Prognostic impact of coronary vasodilator dysfunction on adverse long-term outcome of coronary heart disease. Circulation. 2000;101:1899-1906.