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Volumn 95, Issue 8, 2003, Pages 568-574

Therapeutic advantages of pegylation of interferon alpha in chronic hepatitis C;Ventajas terapéuticas de la pegilación del interferón alfa en la hepatitis crónica C

Author keywords

Antiviral therapy; Combined therapy; Hepatitis C; Interferon; Pegylated interferon; Ribavirin

Indexed keywords

ALPHA INTERFERON; ALPHA2A INTERFERON; ALPHA2B INTERFERON; RIBAVIRIN;

EID: 0042831216     PISSN: 11300108     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (10)

References (41)
  • 1
    • 0024955240 scopus 로고
    • Lipase modified for solubility in organic solvents
    • Baillargeon MW, Sonnet P. Lipase modified for solubility in organic solvents. Ann N Y Acad Sci 1988; 542: 244-9.
    • (1988) Ann. N. Y. Acad. Sci. , vol.542 , pp. 244-249
    • Baillargeon, M.W.1    Sonnet, P.2
  • 2
    • 0025640056 scopus 로고
    • Chemical modification of enzyme molecules to improve their characteristics
    • Cao SG, Zhao Q, Ding Z, Ma L, Yu T, Wang J, et al. Chemical modification of enzyme molecules to improve their characteristics. Ann N Y Acad Sci 1990; 613: 460-7.
    • (1990) Ann. N. Y. Acad. Sci. , vol.613 , pp. 460-467
    • Cao, S.G.1    Zhao, Q.2    Ding, Z.3    Ma, L.4    Yu, T.5    Wang, J.6
  • 3
    • 0019879284 scopus 로고
    • Properties of two urate oxidases modified by the covalent attachment of poly(ethylene glycol)
    • Chen RH, Abuchowski A, Van-Es T, Palczuk N, Davis F. Properties of two urate oxidases modified by the covalent attachment of poly(ethylene glycol). Biochim Biophys Acta 1981; 660: 293-8.
    • (1981) Biochim. Biophys. Acta , vol.660 , pp. 293-298
    • Chen, R.H.1    Abuchowski, A.2    Van-Es, T.3    Palczuk, N.4    Davis, F.5
  • 4
    • 0024952804 scopus 로고
    • Catalytic activity of administered gulonolactone oxidase polyethylene glycol conjugates
    • Hadley KB, Sato P. Catalytic activity of administered gulonolactone oxidase polyethylene glycol conjugates. Enzyme 1989; 42: 225-34.
    • (1989) Enzyme , vol.42 , pp. 225-234
    • Hadley, K.B.1    Sato, P.2
  • 5
    • 0021131208 scopus 로고
    • Physicochemical and biological properties of poly(ethylene glycol)-coupled immunoglobulin G
    • Suzuki T, Kanbara N, Tomono T, Hayashi N, Shinohara I. Physicochemical and biological properties of poly(ethylene glycol)-coupled immunoglobulin G. Biochim Biophys Acta 1984; 788: 248-55.
    • (1984) Biochim. Biophys. Acta , vol.788 , pp. 248-255
    • Suzuki, T.1    Kanbara, N.2    Tomono, T.3    Hayashi, N.4    Shinohara, I.5
  • 7
    • 0023683508 scopus 로고
    • Relationship of effective molecular size to systemic clearance in rats of recombinant interleukin-2 chemically modified with water-soluble polymers
    • Knauf MJ, Bell D, Hirtzer P, Luo Z, Young J, Katre N. Relationship of effective molecular size to systemic clearance in rats of recombinant interleukin-2 chemically modified with water-soluble polymers. J Biol Chem 1988; 263: 15064-70.
    • (1988) J. Biol. Chem. , vol.263 , pp. 15064-15070
    • Knauf, M.J.1    Bell, D.2    Hirtzer, P.3    Luo, Z.4    Young, J.5    Katre, N.6
  • 9
    • 0021248339 scopus 로고
    • Cancer therapy with chemically modified enzymes. I. Antitumor properties of polyethyleneglycol-asparaginase conjugates
    • Abuchowski A, Kazo G, Verhoest C, Van-Es T, Kafkewitz D, Nucci M, et al. Cancer therapy with chemically modified enzymes. I. Antitumor properties of polyethyleneglycol-asparaginase conjugates. Cancer Biochem Biophys 1984; 7: 175-86.
    • (1984) Cancer Biochem. Biophys. , vol.7 , pp. 175-186
    • Abuchowski, A.1    Kazo, G.2    Verhoest, C.3    Van-Es, T.4    Kafkewitz, D.5    Nucci, M.6
  • 10
    • 0019800071 scopus 로고
    • Alteration of the circulating life and antigenic properties of bovine adenosine deaminase in mice by attachment of polyethylene glycol
    • Davis S, Abuchowski A, Park Y, Davis. F. Alteration of the circulating life and antigenic properties of bovine adenosine deaminase in mice by attachment of polyethylene glycol. Clin Exp Immunol 1981; 46: 649-52.
    • (1981) Clin. Exp. Immunol. , vol.46 , pp. 649-652
    • Davis, S.1    Abuchowski, A.2    Park, Y.3    Davis, F.4
  • 11
    • 0022991475 scopus 로고
    • Immunogenicity of polyethylene glycol-modified superoxide dismutase and catalase
    • Nucci ML, Olejarczyk J, Abuchowski A. Immunogenicity of polyethylene glycol-modified superoxide dismutase and catalase. J Free Radic Biol Med 1986; 2: 321-5.
    • (1986) J. Free Radic. Biol. Med. , vol.2 , pp. 321-325
    • Nucci, M.L.1    Olejarczyk, J.2    Abuchowski, A.3
  • 13
    • 0025343062 scopus 로고
    • Characterization and anticancer activity of the micelle-forming polymeric anticancer drug adriamycin-conjugated poly (ethylene glycol)-poly (aspartic acid) block copolymer
    • Yokoyama M, Miyauchi M, Yamada N, Okano T, Sakurai Y, Kataoka K, et al. Characterization and anticancer activity of the micelle-forming polymeric anticancer drug adriamycin-conjugated poly (ethylene glycol)-poly (aspartic acid) block copolymer. Cancer Res 1990; 15: 1693-700.
    • (1990) Cancer Res. , vol.15 , pp. 1693-1700
    • Yokoyama, M.1    Miyauchi, M.2    Yamada, N.3    Okano, T.4    Sakurai, Y.5    Kataoka, K.6
  • 14
    • 0028337034 scopus 로고
    • Distribution and tissue uptake of poly (ethylene glycol) with different molecular weights after intravenous administration to mice
    • Yamaoka T, Tabata Y, Ikada Y. Distribution and tissue uptake of poly (ethylene glycol) with different molecular weights after intravenous administration to mice. J Pharm Sci 1994; 83: 601-6.
    • (1994) J. Pharm. Sci. , vol.83 , pp. 601-606
    • Yamaoka, T.1    Tabata, Y.2    Ikada, Y.3
  • 15
    • 0025126993 scopus 로고
    • Characterization of a polyethylene glycol conjugate of recombinant human interferon-gamma
    • Kita Y, Rohde M, Arakawa T, Fagin K, Fish E, Banerjee K. Characterization of a polyethylene glycol conjugate of recombinant human interferon-gamma. Drug Des Deliv 1990; 6: 157-67.
    • (1990) Drug Des. Deliv. , vol.6 , pp. 157-167
    • Kita, Y.1    Rohde, M.2    Arakawa, T.3    Fagin, K.4    Fish, E.5    Banerjee, K.6
  • 16
    • 0031009603 scopus 로고    scopus 로고
    • Dose-dependent acute clearance of hepatitis C genotype 1 with interferon alfa
    • Lam NP, Neumann A, Gretch D, Whiley T, Perelson A, Layden T. Dose-dependent acute clearance of hepatitis C genotype 1 with interferon alfa. Hepatology 1997; 26: 226-31.
    • (1997) Hepatology , vol.26 , pp. 226-231
    • Lam, N.P.1    Neumann, A.2    Gretch, D.3    Whiley, T.4    Perelson, A.5    Layden, T.6
  • 17
    • 0031149095 scopus 로고    scopus 로고
    • Positional isomers of monopegylated interferon alpha-2a: Isolation, characterization and biological activity
    • Monkarsh SP, Ma Y, Aglione A, Bailon P, Ciolek D, DeBarbieri B, et al. Positional isomers of monopegylated interferon alpha-2a: isolation, characterization and biological activity. Analytical Biochem 1997; 247: 434-40.
    • (1997) Analytical Biochem. , vol.247 , pp. 434-440
    • Monkarsh, S.P.1    Ma, Y.2    Aglione, A.3    Bailon, P.4    Ciolek, D.5    DeBarbieri, B.6
  • 18
    • 0034609586 scopus 로고    scopus 로고
    • Indentication of the major positional isomer of pegylated interferon alpha-2b
    • Wang YS, Youngster S, Bausch J. Indentication of the major positional isomer of pegylated interferon alpha-2b. Biochemistry 2000; 39: 10634-40.
    • (2000) Biochemistry , vol.39 , pp. 10634-10640
    • Wang, Y.S.1    Youngster, S.2    Bausch, J.3
  • 19
    • 0001299981 scopus 로고    scopus 로고
    • A branched methoxy 40 KDA polyethylene glycol (PEG) moiety optimizes the pharmacokinetics of peginterferon alpha-2A and may explain its enchanced efficacy in chronic hepatitis C
    • Algranati NE, S Sy, Modi M. A branched methoxy 40 KDA polyethylene glycol (PEG) moiety optimizes the pharmacokinetics of peginterferon alpha-2A and may explain its enchanced efficacy in chronic hepatitis C. Hepatology 1999; 30: 190.
    • (1999) Hepatology , vol.30 , pp. 190
    • Algranati, N.E.1    Sy, S.2    Modi, M.3
  • 20
    • 0001369293 scopus 로고    scopus 로고
    • Single-dose safety/tolerability and pharmacokinetic/pharmacodynamics (PK/PD) following administration of ascending subcutaneous doses of pegylated-interferon (PEG-IFN) and interferon alfa-2a (IFN alfa-2a) to healthy subjects
    • Xu ZX, Hoffman J, Patel I, Joubert P. Single-dose safety/tolerability and pharmacokinetic/pharmacodynamics (PK/PD) following administration of ascending subcutaneous doses of pegylated-interferon (PEG-IFN) and interferon alfa-2a (IFN alfa-2a) to healthy subjects. Hepatology 1998; 28: 702A.
    • (1998) Hepatology , vol.28
    • Xu, Z.X.1    Hoffman, J.2    Patel, I.3    Joubert, P.4
  • 21
    • 0000553168 scopus 로고    scopus 로고
    • PEG-interferon alpha-2b: Pharmacokinetics, pharmacodynamics, safety and preliminary efficacy data
    • [abstract]
    • Glue P, Fang J, Sabo R, Rouzier-Panis R, Raffanel C, Gupta S, et al. PEG-interferon alpha-2b: Pharmacokinetics, pharmacodynamics, safety and preliminary efficacy data [abstract]. Hepatology 1999; 30: 189A.
    • (1999) Hepatology , vol.30
    • Glue, P.1    Fang, J.2    Sabo, R.3    Rouzier-Panis, R.4    Raffanel, C.5    Gupta, S.6
  • 22
    • 0021840631 scopus 로고
    • Measurement of 2′5′-oligoadenylate synthetase in patients receiving interferon alpha
    • Merrit JA, Borden E, Ball L. Measurement of 2′5′-oligoadenylate synthetase in patients receiving interferon alpha. J Interferon Res 1985; 5: 191-8.
    • (1985) J. Interferon. Res. , vol.5 , pp. 191-198
    • Merrit, J.A.1    Borden, E.2    Ball, L.3
  • 23
    • 0001349460 scopus 로고    scopus 로고
    • Clearance of pegylated (40KDa) interferon alfa-2a(Pegasys) is primarily hepatic
    • Modi MW, Fulton J, Buckmann D, Wright T, Moore D. Clearance of pegylated (40KDa) interferon alfa-2a(Pegasys) is primarily hepatic. Hepatology 2000; 32: 371A.
    • (2000) Hepatology , vol.32
    • Modi, M.W.1    Fulton, J.2    Buckmann, D.3    Wright, T.4    Moore, D.5
  • 24
    • 0034324083 scopus 로고    scopus 로고
    • Pegylated interferon-alpha2b: Pharmacokinetics, pharmacodynamics, safety, and preliminary efficacy data
    • Hepatitis C Intervention Therapy Group
    • Glue P, Fang J, Rouzier-Panis R. Pegylated interferon-alpha2b: pharmacokinetics, pharmacodynamics, safety, and preliminary efficacy data. Hepatitis C Intervention Therapy Group. Clinical Pharmacology & Therapeutics. 2000; 68: 556-67.
    • (2000) Clinical Pharmacology & Therapeutics , vol.68 , pp. 556-567
    • Glue, P.1    Fang, J.2    Rouzier-Panis, R.3
  • 25
    • 17844403232 scopus 로고    scopus 로고
    • A randomized, double-blind trial comparing pegylated interferon alfa-2b to interferon alfa-2b as initial treatment for chronic hepatitis C
    • Lindsay KL, Trepo C, Heintges T, Shiffman M, Gordon S, Hoefs J, et al. A randomized, double-blind trial comparing pegylated interferon alfa-2b to interferon alfa-2b as initial treatment for chronic hepatitis C. Hepatology 2001; 34: 395-403.
    • (2001) Hepatology , vol.34 , pp. 395-403
    • Lindsay, K.L.1    Trepo, C.2    Heintges, T.3    Shiffman, M.4    Gordon, S.5    Hoefs, J.6
  • 26
    • 0000106314 scopus 로고    scopus 로고
    • The pharmacokinetics of pegylated-40K interferon alfa-2a in chronic hepatitis C patients with cirrhosis
    • Heathcote EJ, Pockros P, Fried M, Bain M, DePamphilis J. The pharmacokinetics of pegylated-40K interferon alfa-2a in chronic hepatitis C patients with cirrhosis. Gastroenterology 1999; 116: A735.
    • (1999) Gastroenterology , vol.116
    • Heathcote, E.J.1    Pockros, P.2    Fried, M.3    Bain, M.4    DePamphilis, J.5
  • 27
    • 0030955347 scopus 로고    scopus 로고
    • Therapy of hepatitis C: Patients with cirrhosis
    • Schalm SW FG, Brouwer JT. Therapy of hepatitis C: Patients with cirrhosis. Hepatology 1997; 26: 128S-132S.
    • (1997) Hepatology , vol.26
    • Schalm, S.W.F.G.1    Brouwer, J.T.2
  • 28
    • 0001355826 scopus 로고    scopus 로고
    • Characterization of Pegylated (40kDa) interferon alfa-2a (PEGASYS) in the elderly
    • Martin NE, Modi M, Reddy K. Characterization of Pegylated (40kDa) interferon alfa-2a (PEGASYS) in the elderly. Hepatology 2000; 32: 348A.
    • (2000) Hepatology , vol.32
    • Martin, N.E.1    Modi, M.2    Reddy, K.3
  • 29
    • 0001400946 scopus 로고    scopus 로고
    • Pegylated (40kDa) interferon alfa-2a (PEGASYS) is unaffected by renal impairment
    • Martin P, Mitra S, Farrington K, Martin N, Modi M. Pegylated (40kDa) interferon alfa-2a (PEGASYS) is unaffected by renal impairment. Hepatology 2000; 32: 370A.
    • (2000) Hepatology , vol.32
    • Martin, P.1    Mitra, S.2    Farrington, K.3    Martin, N.4    Modi, M.5
  • 30
    • 0141562183 scopus 로고    scopus 로고
    • Peginterferon alfa-2a (40 KD) (PEGASYS) can be administered safely in patients with end-stage renal disease
    • American Association for the Study of Liver Disease, 52th Annual Meeting; Dallas, EEUU
    • Lamb MW, Marks I, Wynohradnyk L, et al. Peginterferon alfa-2a (40 KD) (PEGASYS) can be administered safely in patients with end-stage renal disease. In: American Association for the Study of Liver Disease, 52th Annual Meeting; Dallas, EEUU; 2001.
    • (2001)
    • Lamb, M.W.1    Marks, I.2    Wynohradnyk, L.3
  • 32
    • 17744389383 scopus 로고    scopus 로고
    • Efficacy and safety of pegylated (40-kd) interferon [alpha]-2a compared with interferon [alpha]-2a in noncirrhotic patients with chronic hepatitis C
    • Reddy KR, Wright T, Pockros P, Shiffman M, Everson G, Reindollar R, et al. Efficacy and safety of pegylated (40-kd) interferon [alpha]-2a compared with interferon [alpha]-2a in noncirrhotic patients with chronic hepatitis C. Hepatology 2001; 33: 433-8.
    • (2001) Hepatology , vol.33 , pp. 433-438
    • Reddy, K.R.1    Wright, T.2    Pockros, P.3    Shiffman, M.4    Everson, G.5    Reindollar, R.6
  • 34
    • 0035934568 scopus 로고    scopus 로고
    • Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: A randomised trial
    • Manns MP, McHutchison J, Gordon S, Rustgi V, Shiffman M, Reindollar R, et al. Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial. Lancet 2001; 358: 958-65.
    • (2001) Lancet , vol.358 , pp. 958-965
    • Manns, M.P.1    McHutchison, J.2    Gordon, S.3    Rustgi, V.4    Shiffman, M.5    Reindollar, R.6
  • 36
    • 0043166207 scopus 로고    scopus 로고
    • Early HCV RNA decline during treatment with peginterferon alfa-2b plus ribavirin or conventional interferon alfa-2b plus ribavirin: Analysis of 80 patients treated at a single center
    • Cornberg M, Hadem J, Bastuerk M. Early HCV RNA decline during treatment with peginterferon alfa-2b plus ribavirin or conventional interferon alfa-2b plus ribavirin: analysis of 80 patients treated at a single center. Hepatologgy 2001; 34: 217A.
    • (2001) Hepatologgy , vol.34
    • Cornberg, M.1    Hadem, J.2    Bastuerk, M.3
  • 37
    • 0036830454 scopus 로고    scopus 로고
    • Side effects of therapy of hepatitis C and their management
    • Fried MW. Side effects of therapy of hepatitis C and their management. Hepatology 2002; 36: S237-44.
    • (2002) Hepatology , vol.36
    • Fried, M.W.1
  • 38
    • 0001474935 scopus 로고    scopus 로고
    • Peginterferon alfa-2a (40kD) (PEGASYS) in combination with ribavirin (RBV): Efficacy and safety results from a phase III, randomised, double-blind multicentre study examining effect of duration of treatment and RBV dose
    • Hadziyannis SJ, Cheinquer H, Morgan T, Diago M, Jensen D, Sette H. Peginterferon alfa-2a (40kD) (PEGASYS) in combination with ribavirin (RBV): efficacy and safety results from a phase III, randomised, double-blind multicentre study examining effect of duration of treatment and RBV dose. J Hepatol 2002; 36: 3.
    • (2002) J. Hepatol. , vol.36 , pp. 3
    • Hadziyannis, S.J.1    Cheinquer, H.2    Morgan, T.3    Diago, M.4    Jensen, D.5    Sette, H.6
  • 39
    • 0036829649 scopus 로고    scopus 로고
    • NIH. National Institutes of Health Consensus Development Conference Statement: Management of Hepatitis C
    • NIH. National Institutes of Health Consensus Development Conference Statement: Management of Hepatitis C. Hepatology 2002; 36: S3-S20.
    • (2002) Hepatology , vol.36


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