Prolonged copper depletion induces expression of antioxidants and triggers apoptosis in SH-SY5Y neuroblastoma cells

Cellular and Molecular Life Sciences

Volumn 60, Issue 8, 2003, Pages 1733-1743

  Lombardo, M F ^a   Ciriolo, M R ^a   Rotilio, G ^a   Rossi, L ^a  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

Antioxidant; Apoptosis; Copper depletion; Mitochondria; Neuroblastoma; Neurodegeneration; Oxidativestress

Indexed keywords

ANTIOXIDANT; CASPASE 3; CASPASE 8; CASPASE 9; COPPER; COPPER SULFATE; COPPER ZINC SUPEROXIDE DISMUTASE; CYTOCHROME C OXIDASE; MANGANESE SUPEROXIDE DISMUTASE; PROTEIN BCL 2; PROTEIN P21; PROTEIN P53; REACTIVE OXYGEN METABOLITE; TRIENTINE;

APOPTOSIS; ARTICLE; CELL VIABILITY; COPPER DEFICIENCY; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; NEUROBLASTOMA CELL; PROTEIN EXPRESSION; UPREGULATION;

ANTIOXIDANTS; APOPTOSIS; CASPASES; CHELATING AGENTS; COPPER; ELECTRON TRANSPORT COMPLEX IV; HUMANS; NEUROBLASTOMA; PROTO-ONCOGENE PROTEINS C-BCL-2; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE; TRIETHYLENETETRAMINE; TUMOR CELLS, CULTURED;

EID: 0042830827     PISSN: 1420682X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00018-003-3153-1     Document Type: Article

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