Effect of fasting on vascular contractility in lean and obese Zucker rats

Clinical Nutrition

Volumn 22, Issue 4, 2003, Pages 359-363

  Wright, G L ^a   Morrison, R ^a   Fultz, M E ^a   Wright, G ^b   McCumbee, W ^a   Wehner, P ^a   Studeny, M ^a  

^a MARSHALL UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 HYDROXYBUTYRIC ACID; ADRENALIN; CHOLESTEROL; GLUCOSE; INSULIN; PHORBOL DIBUTYRATE; POTASSIUM ION; TRIACYLGLYCEROL;

ADRENALIN BLOOD LEVEL; ANIMAL EXPERIMENT; AORTA; ARTICLE; BLOOD PRESSURE; CHOLESTEROL BLOOD LEVEL; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DIET RESTRICTION; FEMALE; GLUCOSE BLOOD LEVEL; INSULIN BLOOD LEVEL; LEAN BODY WEIGHT; NONHUMAN; OBESITY; RAT; RAT STRAIN; SMOOTH MUSCLE CONTRACTILITY; SYSTOLIC BLOOD PRESSURE; TRIACYLGLYCEROL BLOOD LEVEL; VASCULAR SMOOTH MUSCLE; WEIGHT REDUCTION;

EID: 0042830809     PISSN: 02615614     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0261-5614(03)00030-X     Document Type: Article

References (25)

1. Messerli F H. Cardiovascular effects of obesity and hypertension. Lancet 1982; 22: 1165-1168
2. Reaven G. Pathophysiology of insulin resistance in human disease. Physiol Rev 1995; 75: 473-486
3. Kurtz T W, Morris R C, Pershadsingh H A. The fatty Zucker rat as a genetic model of obesity and hypertension. Hypertension 1989; 13: 896-901
4. Ernsburger P, Nelson D O. Refeeding hypertension in dietary obesity. Am J Physiol 1988; 254: R47-R55
5. Kasiske B L, Cleary M P, O'Donnell M P, Keane W F. Effects of genetic obesity on renal structure and function in the Zucker rat. J Lab Clin Med 1985; 106: 598-604
6. Steinberg H O, Chaker H, Leaming R, Johnson A, Brechtel G, Baron A D. Obesity/insulin resistance is associated with endothelial dysfunction. Implications for the syndrome of insulin resistance. J Clin Invest 1996; 97: 2601-2610
7. Hashimoto M, Akishita M, Eto M et al. The impairment of flow-mediated vasodilation in obese men with visceral fat accumulation. Int J Obes Relat Metab Disord 1998; 22: 477-484
8. Tack C J, Ong M K E, Lutterman J A, Smits P. Insulin-induced vasodilation and endothelial function in obesity/insulin resistance. Effect of troglitazone. Diabetologia 1998; 41: 569-576
9. Wu X, Makynen H, Kahonen M, Arvola P, Porsti I. Mesenteric arterial function in vitro in three models of experimental hypertension. J Hypertens 1996; 14: 365-372
10. Walker A B, Dores J, Buckingham R E, Savage M W, Williams G. Impaired insulin-induced attenuation of noradrenaline-mediated vasoconstriction in insulin-resistant obese Zucker rats. Clin Sci (Colch) 1997; 93: 235-241
11. O'Brein S F, McKendrick J D, Radomski M W, Davidge S T, Russell J C. Vascular wall reactivity in conductance and resistance arteries:differential effects of insulin resistance. Can J Physiol Pharmacol 1998; 76: 72-76
12. 2+ handling in the aorta of Zucker obese rats with insulin resistance. Diabetes 1996; 45(Suppl. 13): S55-S58
13. Bohlem J G, Lash J M. Endothelial-dependent vasodilation is preserved in non-insulin-dependent Zucker fatty diabetic rats. Am J Physiol 1995; 268: H2366-H2374
14. Auguet M, Delaflotte A, Braquet P. Increased influence of endothelium in obese Zucker rat aorta. J Pharm Pharmacol 1989; 41: 861-864
15. Huang B S, McCumbee W D, Wright G L. BAYK8644-like contractile effects of a peptide isolated from spontaneously hypertensive rats. Can J Physiol Pharmacol 1988; 66: 332-336
16. Bach A, Bauer M, Schirardin H. Data on lipid metabolism in the genetically obese Zucker rat. Life Sci 1977; 20: 541-550
17. Bray GA. The Zucker fatty rat: a review. Federation Proc 1977; 36: 148-153
18. Triscari J, Bryce G F, Sullivan A C. Metabolic consequences of fasting in old lean and obese Zucker rats. Metabolism 1980; 29: 377-385
19. Triscari J, Greenwood M R C, Sullivan A C. Oxidation and ketogenesis in hepatocytes of lean and obese Zucker rats. Metabolism 1982; 31: 223-228
20. Malewiak M I, Griglio S, Mackay S, Lemonnier D, Rosselin G. Nutritionally induced variations in insulinaemia, blood ketone bodies and plasma and liver triglycerides in genetically obese rats. Diab Metabol 1977; 3: 81-89
21. Herlihy J T. Dietary manipulation of cardiac and aortic smooth muscle reactivity to isoproterenol. Am J Physiol 1984; 246: H369-H323
22. Casalino-Matsuda S M, Linares J A, Finkelberg A B, Goldraij A. Effect of fasting on the contractile activity and metabolism of labelled glucose and arachidonic acid in uteri isolated from intact and ovariectomized rat. Prostaglandins Leukot Essent Fatty Acids 1997; 56(1): 79-83
23. Schramm C M, Gruinstein M M. Assessment of signal transduction mechanisms regulating airway smooth muscle contractility. Am J Physiol 1992; 262: L119-L139
24. Zemel M B, Reddy S, Sewers J R. Insulin attenuation of vasoconstrictor responses to pheneylephrine in Zucker lean and obese rats. AJH 1991; 4: 537-539
25. Larght D W, Desai K M, Änggård E E, Carrier M J. Endothelial dysfunction accompanies a pro-oxidant pro-diabetic challenge in the insulin resistant, obese Zucker rat in vivo. Eur J Pharmacol 2000; 402: 95-99