Microwave assisted synthesis of fungicidal compounds using Knoevenagel condensation in dry media

Journal of the Indian Chemical Society

Volumn 79, Issue 7, 2002, Pages 596-598

  Kidwai, Mazaahir ^a   Sapra, Pooja ^a   Bhushan, Kumar Ranjan ^a  

^a UNIVERSITY OF DELHI   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE; ALUMINUM OXIDE; ANTIFUNGAL AGENT; AROMATIC COMPOUND; HETEROCYCLIC COMPOUND; INDOLE DERIVATIVE; MONTMORILLONITE; QUINOLINE DERIVATIVE; SALICYLIC ACID; SILICA GEL;

ANTIFUNGAL ACTIVITY; ARTICLE; ASPERGILLUS FLAVUS; ASPERGILLUS NIGER; CHEMICAL REACTION; DRUG POTENCY; FUNGICIDAL ACTIVITY; INFRARED SPECTROSCOPY; KNOEVENAGEL CONDENSATION; MICROWAVE IRRADIATION; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; SOLID; SYNTHESIS;

EID: 0042823381     PISSN: 00194522     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. E. Knoevenagel, Chem Ber., 1898, 31, 738.
2. G. Johnes, Org. React., 1967, 15, 204.
3. J. D. Elliott and D. L. Bryan, Chem. Abstr., 1997, 126, 225309.
4. J. A. Cabello, J. M. Campélo, A. Carcia, D. Luna and J. M. Masinas, J. Org. Chem., 1984, 49, 4194.
5. D. Prajapati and J. S. Sandhu, Chem. Lett., 1972, 1945.
6. F. Delgado, J. Tamari, G. Zepeda, M. Landa, R. Miranda and J. Grascia, Synth. Commun., 1995, 25, 753.
7. M. L. Kantam, B. M. Choudary, C. V. Reddy, K. K. Rao and F. Figueras, J. Chem. Soc., Chem. Commun., 1998, 1033.
8. B. C. Hampes, S. A. Kolodziej and A. M. Scates, Tetrahedron Lett., 1998, 391, 2047.
9. D.R. Sidler, J. W. Sager, J. J. Bergan, K. M. Wells, M. Bhupasthy and R. P. Volante, Tetrahedran Assym., 1997, 8, 161; M. Kidwai, N. Negi and S. R. Chowdhury, Acta Pharm., 1994, 45, 511.
10. D.R. Sidler, J. W. Sager, J. J. Bergan, K. M. Wells, M. Bhupasthy and R. P. Volante, Tetrahedran Assym., 1997, 8, 161; M. Kidwai, N. Negi and S. R. Chowdhury, Acta Pharm., 1994, 45, 511.
11. M. Kidwai, N. Negi and S. Kohli, Acta Pharm., 1997, 47, 53.
12. J. K. Kim, P. S. Kwon, T. W. Kwon, S. K. Chung and J. W. Lee, Synth. Commun., 1996, 26, 535.
13. R. Gedye, T. L. Bray, S. M. Duncan and G. Majetich, Tetrahedron, 1906, 27, 4945.
14. D. C. Dittmer, Chem. Ind., 1997, 779; I. Almena, E. Diez-Barra, A. Hoz, J. Ruiz and A. Sanchez-Migallon, J. Heterocycl. Chem., 1998, 35, 1263.
15. D. C. Dittmer, Chem. Ind., 1997, 779; I. Almena, E. Diez-Barra, A. Hoz, J. Ruiz and A. Sanchez-Migallon, J. Heterocycl. Chem., 1998, 35, 1263.
16. M. Kidwai, P. Sapra and B. Dave, Synth. Commun., 2000, 30, 4479; M. Kidwai, K. R. Bhusan and P. Sapra, Bioorg. Med. Chem., 2000, 8, 69; M. Kidwai, N. Negi and P. Misra, J. Indian Chem. Soc., 2000, 77, 46.
17. M. Kidwai, P. Sapra and B. Dave, Synth. Commun., 2000, 30, 4479; M. Kidwai, K. R. Bhusan and P. Sapra, Bioorg. Med. Chem., 2000, 8, 69; M. Kidwai, N. Negi and P. Misra, J. Indian Chem. Soc., 2000, 77, 46.
18. M. Kidwai, P. Sapra and B. Dave, Synth. Commun., 2000, 30, 4479; M. Kidwai, K. R. Bhusan and P. Sapra, Bioorg. Med. Chem., 2000, 8, 69; M. Kidwai, N. Negi and P. Misra, J. Indian Chem. Soc., 2000, 77, 46.
19. G. Bram and G. Decordts, Tetrahedron Lett., 1980, 21, 5011.
20. Substituted aromatic heterocyclic ketones also undergo Knoevenagel condensation in similar reaction condition as reported in literature (P. de la Cruz, E. D. Barra, A. Loupy and F. Langa, Tetrahedron Lett., 1996, 37, 1113).
21. H. W. Seeley and P. J. Van Denmark, "Microbes in Action", Freeman WH & Co, 1972.
22. F. Knvessel and F. G. Weirich, Dermatologia, 1972, 145, 233; Clotrimazole was not used as a standard drug as it is not easily available in pure form, marketed along with additives; on the other hand, salicylic acid is well known to show activity against diverse fungal strains.
23. G. Bram, A. Loupy and M. Majoub, Tetrahedron Lett., 1990, 46, 5167.