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Procedure of 8 by conventional heating; A solution of 10 mL of dry benzene (distilled from sodium), 2.58g(16,6mmol) of 1-naphthaldehyde, 2.90g(18.1mmol) of diethyl malonate, 2mL of piperidine and molecular sieves were stirred (with reflux condenser) at 55°C for 24hr. The solution was cooled to room temperature and water was added. The mixture was extracted with ethyl acetate. The organic phases were dried with magnesium sulfate.The solution was filtered and concentrated under vacuum. The mixture was purified by silicagel chromatography to give 2.2g(7.38mmole, 44.7%) of 8.
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