Changes of ICAM-1, Mac-1 and MPO activity in focal cerebral ischemic mice

Fudan University Journal of Medical Sciences

Volumn 30, Issue 4, 2003, Pages 304-307

  Wang, Zhi Qiu ^a   Chen, Xian Cheng ^a   Yang, Guo Yuan ^b   Zhou, Liang Fu ^a  

^a FUDAN UNIVERSITY   (China)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Adhesion molecule; Cerebral ischemia; Endothelium; Inflammatory reaction; Leukocytes; Mice

Indexed keywords

ADHESION; CELLS;

INFLAMMATORY REACTIONS;

MEDICAL EDUCATION;

CD11B ANTIGEN; INTERCELLULAR ADHESION MOLECULE 1; MYELOPEROXIDASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BASAL GANGLION; BRAIN CORTEX; BRAIN ISCHEMIA; ENZYME ACTIVITY; INFLAMMATION; LEUKOCYTE; MOUSE; NONHUMAN; OCCLUSIVE CEREBROVASCULAR DISEASE; PROTEIN EXPRESSION;

EID: 0042817945     PISSN: 16728467     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Barone FC, Feuerstein GZ. Inflammatory mediators and stroke: new opportunities for novel therapeutics. J Cereb Blood Flow Metab, 1999,19: 819
2. Yang GY, Mao Y, Zhou LF, et al. Expression of intercellular adhesion molecule 1 (ICAM-1) is reduced in permanent focal cerebral ischemic mouse brain using an adenoviral vector to induce overexpression of interleukin-1 receptor antagonist. Brain Res Mol, 1999,65:143
3. Barone FC, Arvin B, White RF, et al. Tumor necrosis factor-α: a mediator of facal ischemic brain injury. Stroke, 1997,28:1233
4. Zhang WD, Smith C, Shapiro A, et al. Increased expression of bioactive chemokines in human cerebromicrovascular endothelial cells and astrocytes subjected to simulated ischemia in vitro. J Neuroimmunol, 1999,101: 148
5. Stoll G, Jander S, Schroeter M. Inflammation and glial responses in ischemic brain lesions. Prog Neurobiol, 1998,56:149
6. Prestigiaoomo CJ, Kim SC, Connolly ES, et al. CD18-mediated neutrophil recruitment contributes to the pathogenesis of reperfused but not non-reperfused stroke. Stroke, 1999,30:1110
7. 2 or products of activated neutrophils. Am J Med, 1991,91:89
8. Kawai N, Okauchi M, Morisaki K, et al. Effects of ddlayed intraischemic and postischemic hypothermia on a focal model of transient cerebral ischemia in rats. Stroke, 2000,31:1982
9. Gregersen R, Lambertsen K, Finsen B. Microglia and macrophages are the major source of tumor necrosis factor in permanent middle cerebral artery occlusion in mice. J Cereb Blood Flow Metab, 2000,20:53