Effects of propofol on bronchoconstriction and bradycardia induced by vagal nerve stimulation

Acta Anaesthesiologica Scandinavica

Volumn 47, Issue 9, 2003, Pages 1059-1063

  Hashiba, E ^a   Hirota, K ^a   Suzuki, K ^a   Matsuki, A ^a  

^a HIROSAKI UNIVERSITY   (Japan)

Author keywords

Bradycardia; Bronchoconstriction and vagal nerve stimulation; Propofol

Indexed keywords

ATROPINE; PROPOFOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIAL PRESSURE; ARTICLE; BRADYCARDIA; BRONCHOSCOPY; BRONCHOSPASM; CONTROLLED STUDY; DOG; HEART RATE; LOW DRUG DOSE; NONHUMAN; PRIORITY JOURNAL; VAGUS NERVE STIMULATION;

ANESTHETICS, INTRAVENOUS; ANIMALS; ATROPINE; BRONCHOCONSTRICTION; DOGS; ELECTRIC STIMULATION; HEART RATE; PROPOFOL; VAGUS NERVE;

EID: 0042736828     PISSN: 00015172     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-6576.2003.00228.x     Document Type: Article

References (23)

1. Pizov R, Brown RH, Weiss YS et al. Wheezing during induction of general anesthesia in patients with and without asthma: a randomized blinded trial. Anesthesiology 1995; 82: 1111-6.
2. Wu RSC, Wu DC, Sum DCW, Bishop MJ. Comparative effects of thiopentone and propofol on respiratory resistance after tracheal intubation. Br J Anaesth 1996; 77: 735-8.
3. Cigarini I, Bonner F, Lorino AM, Harf A. Comparison of the effects of fentanyl on respiratory mechanics under propofol or thiopental anaesthesia. Acta Anaesthesiol Scand 1990; 34: 253-6.
4. Conti G, Dell'Utri D, Vilardi V et al. Propofol induces bronchodilation in mechanically ventilated chronic obstructive pulmonary disease (COPD) patients. Acta Anaesthesiol Scand 1993; 37: 105-9.
5. Hirota K, Sato T, Hashimoto Y et al. Relaxant effect of propofol on the airway in dogs. Br J Anaesth 1999; 83: 292-5.
6. Kabara S, Hirota K, Hashiba E, Yoshioka H, Kudo T, Sato T, Matsuki A. Comparison of relaxant effects of propofol on methacholine-induced bronchoconstriction in dogs with and without vagotomy. Br J Anaesth 2001; 86: 249-53.
7. Otomo N, Hirota K, Hashimoto Y et al. Measurement of bronchodilation using a superfine fibreoptic bronchoscope. Br J Anaesth 1997; 78: 583-5.
8. Gal TJ. Bronchial hyperresponsiveness and anesthesia: physiologic and therapeutic perspectives. Anesth Analg 1994; 78: 559-73.
9. Cohendy R, Lefrant JY, Laracine M, Rabiere T, Eledjam JJ. Effect of fentanyl on ventilatory resistances during barbiturate general anaesthesia. Br J Anaesth 1992; 69: 595-8.
10. Baraka A. Severe bradycardia following propofolsuxamethonium sequence. Br J Anaesth 1988; 61: 482-3.
11. Egan TD, Brock-Utne JG. Asystole after anesthesia induction with a fentanyl, propofol, and succinylcholine sequence. Anesth Analg 1991; 73: 818-20.
12. Deutschman CS, Harris AP, Fleisher LA. Changes in heart rate variability under propofol anesthesia: a possible explanation for propofol-induced bradycardia. Anesth Analg 1994; 79: 373-7.
13. Tramèr MR, Moore RA, Mcquay HJ. Propofol and bradycardia: causation, frequency and severity. Br J Anaesth 1997; 78: 642-51.
14. 2O anaesthesia. Can J Anaesth 1990; 37: 416-9.
15. Hirota K, Hashiba E, Kabara S, Yoshioka H, Ishihara H, Matsuki A. Unvetilated airway is time-dependently constricted in paralyzed dogs. Anesthesiology 2001; 95: 1480-4.
16. Brown RH, Mitzner W, Zerhouni E, Hirshman CA. Direct visualization of bronchodilation induced by inhalational anesthesia using high-resolution computed tomography. Anesthesiology 1993; 78: 295-300.
17. Brown RH, Wagner EM. Mechanisms of bronchoprotection by anesthetic induction agents. Propofol versus Ketamine. Anesthesiology 1999; 90: 822-8.
18. Hirota K, Hashimoto Y, Lambert DG. Interaction of intravenous anesthetics with recombinant human M1-M3 muscarinic receptors expressed in chinese hamster ovary cells. Anesth Analg 2002; 95: 1607-10.
19. Hashiba E, Sato T, Hirota K, Hashimoto Y, Matsuki A. The relaxant effect of propofol on guinea pig tracheal muscle is independent of airway epithelial function and beta-adrenoceptor activity. Anesth Analg 1999; 89: 191-6.
20. Yamakage M, Hirshman CA, Croxton TL. Inhibitory effects of thiopental, ketamine, and propofol on voltage-dependent Ca2+ channels in porcine tracheal smooth muscle cells. Anesthesiology 1995; 83: 1274-82.
21. Lin CC, Shyr MH, Tan PP et al. Mechanisms underlying the inhibitory effect of propofol on the contraction of canine airway smooth muscle. Anesthesiology 1999; 91: 750-9.
22. Cembala TM, Sherwin JD, Tidmarsh MD, Appadu BL, Lambert DG. Interaction of neuromuscular blocking drugs with recombinant human m1-m5 muscarinic receptors expressed in Chinese hamster ovary cells. Br J Pharmacol 1998; 125: 1088-94.
23. Krassioukov AV, Gelb AW, Weaver LC. Action of propofol on central sympathetic mechanisms controlling blood pressure. Can J Anaesth 1993; 40: 761-9.