Synthesis of 5-(4-alkylsulfanyl-[1,2,5]thiadiazol-3-yl)-3-methyl-1,2,3, 4-tetrahydropyrimidine oxalate salts and their evaluation as muscarinic receptor agonists

Archiv der Pharmazie

Volumn 336, Issue 4-5, 2003, Pages 230-235

  Jung, Myung Hee ^a   Park, Jewn Giew ^b   Park, Woo Kyu ^a  

^a Korea Research Institute of Chemical Technology   (South Korea)

^b MAYO CLINIC CANCER CENTER   (United States)

Author keywords

1,2,3,4 tetrahydropyrimidine; Alzheimer's disease; Muscarinic receptor agonists; Xanomeline

Indexed keywords

5 (4 SULFANYL 1,2,5 THIADIAZOL 3 YL) 3 METHYL 1,2,3,4 TETRAHYDROPYRIMIDINE OXALATE; ARECOLINE; MILAMELINE; MUSCARINIC AGENT; OXALIC ACID DERIVATIVE; UNCLASSIFIED DRUG; XANOMELINE;

ALZHEIMER DISEASE; ARTICLE; BINDING AFFINITY; BINDING ASSAY; CHEMICAL MODIFICATION; CHEMICAL REACTION; CYCLIZATION; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; IN VITRO STUDY; MOLECULAR CLONING; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; REACTION ANALYSIS; REDUCTION; STEREOISOMERISM; STRECKER SYNTHESIS; SUBSTITUTION REACTION;

EID: 0042736116     PISSN: 03656233     EISSN: None     Source Type: Journal    
DOI: 10.1002/ardp.200300730     Document Type: Article

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