Synthesis of 5-(4-alkoxy-[1,2,5]thiadiazol-3-yl)-3-methyl-1,2,3,4- tetrahydropyrimidine oxalate salts and their evaluation as muscarinic receptor agonists

Archiv der Pharmazie

Volumn 333, Issue 5, 2000, Pages 113-117

  Park, Jewn Giew ^a   Lee, Mi Jeoung ^a   Kong, Jae Yang ^a   Jung, Myung Hee ^a  

^a Korea Research Institute of Chemical Technology   (South Korea)

Author keywords

1,2,3,4 tetrahydropyrimidine; Binding assay; Milameline; Muscarinic receptor agonists

Indexed keywords

5 (4 ALKOXY[1,2,5]THIADIAZOL 3 YL) 3 METHYL 1,2,3,4 TETRAHYDROPYRIMIDINE OXALATE; ARECOLINE; MILAMELINE; MUSCARINIC AGENT; MUSCARINIC RECEPTOR; UNCLASSIFIED DRUG; XANOMELINE;

ARTICLE; BINDING AFFINITY; BINDING KINETICS; CHEMICAL REACTION; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; IN VITRO STUDY; PRIORITY JOURNAL; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION;

ALZHEIMER DISEASE; BINDING, COMPETITIVE; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; MUSCARINIC AGONISTS; N-METHYLSCOPOLAMINE; PROTEIN BINDING; PYRIMIDINES; RECEPTOR, MUSCARINIC M1; RECEPTORS, MUSCARINIC; RECOMBINANT PROTEINS; THIADIAZOLES;

EID: 0034043486     PISSN: 03656233     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-4184(20005)333:5<113::AID-ARDP113>3.0.CO;2-9     Document Type: Article

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