Generation of cyanogen-free transgenic cassava

Planta

Volumn 217, Issue 3, 2003, Pages 367-373

  Siritunga, Dimuth ^a   Sayre, Richard T ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

Cyanide; Cyanogenic glycoside; Cytochrome P450; Linamarin; Manihot

Indexed keywords

CATALYSIS; FOOD PRODUCTS; GROWTH KINETICS;

TOXIC FOODS;

PLANTS (BOTANY);

CYTOCHROME P-450 ENZYME SYSTEM; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, PLANT; GLYCOSIDES; ISOENZYMES; MANIHOT; NITRILES; PLANT LEAVES; PLANT ROOTS; PLANTS, GENETICALLY MODIFIED;

EMBRYOPHYTA; MANIHOT; MANIHOT ESCULENTA;

EID: 0042710888     PISSN: 00320935     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00425-003-1005-8     Document Type: Article

References (38)

1. Anderssen M, Bush P, Svendsen I, Moller B (2000) Cytochromes P450 from cassava catalyzing the first steps in the biosynthesis of the cyanogenic glycosides linamarin and lotaustralin. J Biol Chem 275:1966-1975
2. Arias-Garzon D, Sayre R (1993) Tissue specific inhibition of transient gene expression in cassava (Manihot eseulenta Crantz). Plant Sci 93:121-130
3. Arias-Garzon D, Sayre R (2000) Genetic engineering approaches to reducing the cyanide toxicity in cassava (Manihot esculenta, Crantz). In: Carvalho L, Thro AM, Vilarinhos AD (eds) Proceedings of the fourth international scientific meeting of the Cassava Biotechnology Network, Embrapa, Brasilia, pp 213-221
4. Arias-Garzon D, Sarria R, Gelvin S, Sayre R (1994) New Agrobacterium tumefaciens plasmids for cassava transformation. In: Roca WM, Thro AM (eds) Proceedings of the second international scientific meeting of the Cassava Biotechnology Network, Bogor, Indonesia, pp 245-256
5. Bediako M, Tapper B, Pritchard G (1981) Metabolism synthetic site and translocation of cyanogenic glucoside in cassava. In: Terry ER (ed) Proceedings of the first triennial root crops symposium of the International Society for Tropical Root Crops. IDRC, Canada, pp 143-148
6. Best R, Hargrove T (1994) Casssava: the latest facts about an ancient crop. CIAT Publication, Cali, Colombia
7. Bevan W, Barnes W, Chilton M (1983) Structure and transcription of the nopaline synthase gene region of T-DNA. Nucleic Acids Res 11:369-385
8. Brusslan J, Tobin E (1992) Light-independent developmental regulation of cab gene expression in Arabidopsis thaliana seedlings. Proc Natl Acad Sci USA 89:7791-7795
9. Doyle J, Doyle J (1990) Isolation of plant DNA from fresh tissue. Focus 12:13-15
10. Du L, Bokanga M, Moller B, Halkier B (1995) The biosynthesis of cyanogenic glucosides in roots of cassava. Phytochemistry 39:323-326
11. Gamborg O, Miller R, Ojima K (1968) Nutrient requirement of suspension cultures of soybean and carrot cells. Exp Cell Res 50:151-158
12. Hughes J, Carvalho F, Hughes M (1994) Purification, characterization and cloning of hydroxynitrile lyase from cassava (Manihot esculenta Crantz). Arch Biochem Biophys 311:496-502
13. Ikoigbo B (1980) Nutritional implications of projects giving high priority to the production of staples of low nutritive quality. The case of cassava in the humid tropics of West Africa. Food and Nutrition Bulletin, United Nations University, Tokyo, vol 2, pp 1-10
14. Kahn R, Bak S, Svendsen I, Halkier B, Moller B (1997) Isolation and reconstitution of cytochrome P450ox and in vitro reconstitution of the entire biosynthetic pathway of the cyanogenic glucoside dhurrin from sorghum. Plant Physiol 115:1661-1670
15. Kakes P (1990) Properties and functions of the cyanogenic system in higher plants. Euphytica 48:25-43
16. Koch B, Nielsen V, Halkier B, Olsen C, Møller B (1992) The biosynthesis of cyanogenic glycosides in seedlings of cassava (Manihot esculenta Crantz). Arch Biochem Biophys 292:141-150
17. Latham M (1979) Human nutrition in tropical Africa. Food and Agriculture Organization of the United Nations, Rome
18. Li H-Q, Sautter C, Potrykus I, Puonti-Kaerlas J (1996) Genetic transformation of cassava (Manihot esculenta Crantz). Nature Biotechnol 14:736-740
19. Makame M, Akoroda M, Hahn S (1987) Effects of reciprocal stem grafts on cyanide translocation in cassava. J Agric Sci Cambridge 109:605-608
20. McMahon J, Sayre R (1994) Regulation of cyanogenic potential in cassava (Manihot esculenta Crantz). In: Roca WM, Thro AM (eds) Proceedings of the second international scientific meeting of the Cassava Biotechnology Network, Bogor, Indonesia, pp 423-438
21. McMahon J, White W, Sayre R (1995) Cyanogenesis in cassava (Manihot esculenta Crantz). J Exp Bot 46:731-741
22. Mkpong O, Yan H, Chism G, Sayre R (1990) Purification, characterization, and localization of linamarase in cassava. Plant Physiol 93:176-181
23. Murashige T, Skoog F (1962) A revised medium for rapid growth and bio assays with tobacco tissue culture. Physiol Plant 15:473-497
24. Osuntokun B (1991) Cassava diet, chronic cyanide intoxification and neuropathy in Nigerian Africans. World Rev Nutr Diet 36:141-173
25. Ramanujam T, Indira P (1984) Effect of girdling on the distribution of total carbohydrates and hydrocyanic acid in cassava. Indian J Plant Phys 27:355-360
26. Rosling H (1974) Cassava cyanide and epidemic spastic paraparesis: a study in Mozambique on dietery cyanide exposure. ACTA Universitatis Upsalienis, Ph.D. thesis, Uppsala University, Sweden
27. Rosling H, Mlingi N, Tylleskar T, Banea M (1992) Causal mechanisms behind human diseases induced by cyanide exposure from cassava. In: Roca WM, Thro AM (eds) Proceedings of the first international scientific meeting of the Cassava Biotechnology Network, Cartegena, Cali, Colombia, pp 366-375
28. Sambrook J, Fritsch E, Maniatis J (1989) Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
29. Selmar D (1993) Transport of cyanogenic glucosides: linustatin uptake in Hevea cotyledons. Planta 191:191-199
30. Selmar D, Lieberei R, Biehl R (1988) Mobilization and utilization of cyanogenic glycosides: the linustatin pathway. Plant Physiol 86:711-716
31. TYR which catalyzes the committed step in the biosynthesis of the cyanogenic glucoside dhurrin in Sorghum bicolor (L.) Moench. Proc Natl Acad Sci USA 91:9740-9744
32. Soni R, Murray A (1994) Isolation of intact DNA and RNA from plant tissue. Anal Biochem 218:470-476
33. Stitt M, Sonnewald U (1995) Regulation of metabolism in transgenic plants. Annu Rev Plant Physiol Plant Mol Biol 46:341-368
34. Tylleskar T, Banea M, Bikangi N, Cooke R, Poulter N, Rosling H (1992) Cassava cyanogens and konzo, an upper motor neuron disease found in Africa. Lancet 339:208-211
35. Vincent J (1985) A manual for the practical study of root-nodule bacteria. IBP handbook No. 15
36. Wheatley C, Orrego J, Sanchez T, Granados E (1993) Quality evaluation of cassava core collection at CIAT. In: Roca WM, Thro AM (eds) Proceedings of the first international scientific meeting of the Cassava Biotechnology Network, Cartegena, Cali, Colombia, pp 255-264
37. White W, McMahon J, Sayre R (1994) Regulation of cyanogenesis in cassava. Acta Hort 375:69-77
38. White W, Arias-Garzon D, McMahon J, Sayre R (1998) Cyanogenesis in cassava: the role of hydroxynitrile lyase in root cyanide production. Plant Physiol 116:1219-1225