Emotion regulation and touch in infants: The role of cholecystokinin and opioids

Peptides

Volumn 24, Issue 5, 2003, Pages 779-788

  Weller, Aron ^a   Feldman, Ruth ^a  

^a BAR ILAN UNIVERSITY   (Israel)

Author keywords

Cholecystokinin; Emotion regulation; Infant mother attachment; Infants; Opioid neuropeptides; Preterm infants; Rats; Self regulation; Sheep; Stress reactivity; Touch; Ultra vocalization

Indexed keywords

CHOLECYSTOKININ; NEUROPEPTIDE; OPIATE;

AUTOREGULATION; BEHAVIOR; CHILD CARE; CHILD GROWTH; DEPRESSION; DEVELOPMENT; DEVELOPMENTAL STAGE; EMOTION; EMOTIONAL ATTACHMENT; EMOTIONAL DISORDER; EXPERIMENTAL MODEL; GENETIC ANALYSIS; HUMAN; HYPOTHESIS; INFANT; MATERNAL CARE; MENTAL DISEASE; MOTHER CHILD RELATION; MOTIVATION; NEUROCHEMISTRY; NEUROPSYCHOLOGY; NONHUMAN; PATHOPHYSIOLOGY; PERINATAL PERIOD; POSTNATAL CARE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; REGULATORY MECHANISM; REVIEW; RISK FACTOR; SOCIAL ASPECT; SPECIES DIFFERENCE; STRESS; TACTILE STIMULATION; TOUCH;

ANIMALIA; MACROPUS SP.; OVIS ARIES;

EID: 0042706187     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0196-9781(03)00118-9     Document Type: Review

References (131)

1. Agmo A., Barreau S., Lemaire V. Social motivation in recently weaned rats is modified by opiates. Dev. Neurosci. 19:1997;505-520.
2. Agmo A., Galvan A., Talamantes B. Reward and reinforcement produced by drinking sucrose: two processes that may depend on different neurotransmitters. Pharmacol. Biochem. Behav. 52:1995;403-414.
3. Anand K.J., Scalzo F.M. Can adverse neonatal experiences alter brain development and subsequent behavior? Biol. Neonate. 77:2000;69-82.
4. Berridge K.C. Food reward: brain substrates of wanting and liking. Neurosci. Biobehav. Rev. 20:1996;1-25.
5. Berridge K.C., Robinson T.E. What is the role of dopamine in reward: hedonic impact, reward learning, or incentive salience? Brain Res. Rev. 28:1998;309-369.
6. Blass E.M., Fillion T.J., Weller A., Brunson L. Separation of opioid from nonopioid mediation of affect in neonatal rats: nonopioid mechanisms mediate maternal contact influences. Behav. Neurosci. 104:1990;625-636.
7. Blass E.M., Fitzgerald E. Milk-induced analgesia and comforting in 10-day-old rats: opioid mediation. Pharmacol. Biochem. Behav. 29:1988;9-13.
8. Blass E.M., Fitzgerald E., Kehoe P. Interactions between sucrose, pain and isolation distress. Pharmacol. Biochem. Behav. 26:1987;483-489.
9. Blass EM, Kehoe P. Behavioral characteristics of emerging opioid systems in newborn rats. In: Krasnegor NA, Blass EM, Hofer MA, Smotherman WP, editors. Perinatal development, a psychobiological perspective. New York: Academic Press; 1987. p. 61-82.
10. Blass E.M., Shide D.J. Endogenous cholecystokinin reduces vocalization in isolated 10-day-old rats. Behav. Neurosci. 107:1993;488-492.
11. Bowlby J. Attachment and loss, vol. 1. Attachment. New York: Basic; 1969.
12. Bowlby J. Attachment and loss, vol. 2. Separation. New York: Basic; 1973.
13. Brake S.C. Suckling infant rats learn a preference for a novel stimulus paired with milk delivery. Science. 211:1981;506-508.
14. Brazelton TB, Tronick E, Adamson L, Als H, Wise S. Parent infant interaction. Oxford: Elsevier; 1975.
15. Buss K.A., Goldsmith H.H. Fear and anger regulation in infancy: effects on the temporal dynamics of affective expression. Child Dev. 69:1998;359-374.
16. Caba M., Poindron P., Krehbiel D., Levy F., Romeyer A., Venier G. Naltrexone delays the onset of maternal behavior in primiparous parturient ewes. Pharmacol. Biochem. Behav. 52:1995;743-748.
17. Caldji C., Diorio J., Meaney M.J. Variations in maternal care in infancy regulate the development of stress reactivity. Biol. Psychiatry. 48:2000;1164-1174.
18. Caldji C., Francis D., Sharma S., Plotsky P.M., Meaney M.J. The effects of early rearing environment on the development of GABAA and central benzodiazepine receptor levels and novelty-induced fearfulness in the rat. Neuropsychopharmacology. 22:2000;219-229.
19. Calkins S.D., Fox N.A. Self-regulatory processes in early personality development: a multilevel approach to the study of childhood social withdrawal and aggression. Dev. Psychopathol. 14:2002;477-498.
20. Carden S.E., Barr G.A., Hofer M.A. Differential effects of specific opioid receptor agonists on rat pup isolation calls. Brain Res. Dev. Brain Res. 62:1991;17-22.
21. Carden S.E., Bortot A.T., Hofer M.A. Ultrasonic vocalizations are elicited from rat pups in the home cage by pentylenetetrazol and U50,488, but not naltrexone. Behav. Neurosci. 107:1993;851-859.
22. Carden S.E., Davachi L., Hofer M.A. U50,488 increases ultrasonic vocalizations in 3-, 10-, and 18-day-old rat pups in isolation and the home cage. Dev. Psychobiol. 27:1994;65-83.
23. Carden S.E., Hofer M.A. Socially mediated reduction of solation distress in rat pups is blocked by naltrexone but not by Ro 15-1788. Behav. Neurosci. 104:1990;457-463.
24. Carden S.E., Hofer M.A. Independence of benzodiazepine and opiate action in the suppression of isolation distress in rat pups. Behav. Neurosci. 104:1990;160-166.
25. Carden S.E., Hofer M.A. The effect of opioid and benzodiazepine antagonists on dam-induced reductions in rat pup isolation distress. Dev. Psychobiol. 23:1990;797-808.
26. Carden S.E., Hofer M.A. Isolation-induced vocalization in Wistar rat pups is not increased by naltrexone. Physiol. Behav. 49:1991;1279-1282.
27. Carden S.E., Hernandez N., Hofer M.A. The isolation and companion comfort responses of 7- and 3-day-old rat pups are modulated by drugs active at the opioid receptor. Behav. Neurosci. 110:1996;324-330.
28. De Passillé A.M.B., Christopherson R., Rushen J. Non-nutritive sucking by the calf and postprandial secretion of insulin, CCK, and gastrin. Physiol. Behav. 54:1993;1069-1073.
29. DiPietro J.A., Cusson R.M., Caughy M.O., Fox N.A. Behavioral and physiologic effects of nonnutritive sucking during gavage feeding in preterm infants. Pediatr. Res. 36:1994;207-214.
30. Dwyer C.M., McLean K.A., Deans L.A., Chirnside J., Calvert S.K., Lawrence A.B. Vocalizations between mother and young in sheep: effects of breed and maternal experience. Appl. Anim. Behav. Sci. 58:1998;105-119.
31. Feldman R, Eidelman AI. Direct and indirect effects of maternal milk on the neurobehavioral and cognitive development of premature infants. Dev Psychobiol 2003;43(August).
32. Feldman R., Eidelman A.I. Skin-to-skin contact (Kangaroo Care) accelerates autonomic and neurobehavioural maturation in preterm infants. Dev. Med. Child Neurol. 45:2003;274-281.
33. Feldman R., Eidelman A.I., Sirota L., Weller A. Comparison of skin-to-skin (kangaroo) and traditional care: parenting outcomes and preterm infant development. Pediatrics. 110:2002;16-26.
34. Feldman R., Weller A., Sirota L., Eidelman A.I. Skin-to-skin contact (Kangaroo care) promotes self-regulation in premature infants: sleep-wake cyclicity, arousal modulation, and sustained exploration. Dev. Psychol. 38:2002;194-207.
35. Feldman R., Weller A., Sirota L., Eidelman A.I. Testing a family intervention hypothesis: the contribution of mother-infant skin-to-skin contact (Kangaroo care) to family interaction, proximity, and touch. J. Fam. Psychol. 17:2003;94-107.
36. Ferber S.G., Kuint J., Weller A., Feldman R., Dollberg S., Arbel E.et al. Massage therapy by mothers and trained professionals enhances weight gain in preterm infants. Early Hum. Dev. 67:2002;37-45.
37. Ferber S.G., Laudon M., Kuint J., Weller A., Zisapel N. Massage therapy by mothers enhances the adjustment of circadian rhythms to the nocturnal period in full-term infants. J. Dev. Behav. Pediatr. 23:2002;410-415.
38. Field T. Infants of depressed mothers. Dev. Psychopathol. 4:1992;49-66.
39. Field T. The effects of mother's physical and emotional unavailability on emotion regulation. Monogr. Soc. Study Child Dev. 59:1994;208-228.
40. Field T. Massage therapy for infants and children. J. Behav. Dev. Pediatr. 16:1995;105-111.
41. Field T., Healy B., Goldstein S., Guthertz M. Behavior state matching in mother-infant interactions of nondepressed versus depressed mother-infant dyads. Dev. Psychol. 26:1990;7-14.
42. Field T., Pickens J., Fox N.A., Nawrocki T., Gonzalez J. Vagal tone in infants of depressed mothers. Dev. Psychopathol. 7:1995;227-231.
43. Field T., Sandberg D., Garcia R., Vega-Lahr N., Goldstein S., Guy L. Prenatal problems, postpartum depression, and early mother-infant interactions. Dev. Psychol. 21:1985;250-253.
44. Flett G.L., Blankstein K.R., Obertynski M. Affect intensity, coping styles, mood regulation expectancies, and depressive symptoms. Pers. Ind. Diff. 20:1996;221-228.
45. Francis D.D., Caldji C., Champagne F., Plotsky P.M., Meaney M.J. The role of corticotropin-releasing factor-norepinephrine systems in mediating the effects of early experience on the development of behavioral and endocrine responses to stress. Biol. Psychiatry. 46:1999;1153-1166.
46. Garcia-Coll C.T., Emmons L., Vohr B.R., Ward A.M., Brann B.S., Shaul P.W.et al. Behavioral responsiveness in preterm infants with intraventricular hemorrhage. Pediatrics. 81:1988;412-418.
47. Gazzolo D., Masetti P., Meli M. Kangaroo care improves post-extubation cardiorespiratory parameters in infants after open heart surgery. Acta Pediatr. 89:2000;728-729.
48. Gill N.E., Behnke M., Conlon M., Anderson G.C. Nonnutritive sucking modulates behavioral state for preterm infants before feeding. Scand. J. Caring Sci. 6:1992;3-7.
49. Gill N.E., Behnke M., Conlon M., McNeely J.B., Anderson G.C. Effect of nonnutritive sucking on behavioral state in preterm infants before feeding. Nurs. Res. 37:1988;347-350.
50. Goodman S.H., Gotlib I.H. Risk for psychopathology in the children of depressed mothers: a developmental model for understanding mechanisms of transmission. Psychol. Rev. 106:1999;458-490.
51. Goodwin G.A., Barr G.A. Evidence for opioid and nonopioid processes mediating adaptive responses of infant rats that are repeatedly isolated. Dev. Psychobiol. 31:1997;217-227.
52. Goursaud A.-P. Nowak R 2-NAP, a peripheral CCK-A receptor antagonist, modulates the development of a preference for the mother by the newborn lamb. Pharmacol. Biochem. Behav. 67:2000;1-9.
53. Gray L., Watt L., Blass E.M. Skin-to-skin contact is analgesic in healthy newborns. Pediatrics. 105:2000;e14.
54. Harvey A.T., Hennessy M.B. Corticotropin-releasing factor modulation of the ultrasonic vocalization rate of isolated rat pups. Brain Res. Dev. Brain Res. 87:1995;125-134.
55. Herman B.H., Panksepp J. Effects of morphine and naloxone on separation distress and approach attachment: evidence for opiate mediation of social affect. Pharmacol. Biochem. Behav. 9:1978;213-220.
56. Hofer M.A. Relationships as regulators: a psychobiological perspective on bereavement. Psychosom. Med. 46:1984;183-197.
57. Hofer M.A. Hidden regulators in attachment, separation, and loss. Monogr. Soc. Res. Child Dev. 59:1994;192-207.
58. Hofer MA. Hidden regulators: implication for a new understanding of attachment, separation, and loss. In: Golberg S, Muir R, Kerr J, editors. Attachment theory: social, developmental, and clinical perspectives. Hillsdale, NJ: Analytic Press; 1995. p. 203-30.
59. Hofer M.A. Multiple regulators of ultrasonic vocalization in the infant rat. Psychoneuroendocrinology. 21:1996;203-217.
60. Hudson R., Labra-Cardero D., Mendoza-Soylovna A. Sucking, not milk, is important for the rapid learning of nipple-search odors in newborn rabbits. Dev. Psychobiol. 41:2002;226-235.
61. Hurst N.M., Valentine C.J., Renfro L., Burns P., Ferlic L. Skin-to-skin holding in the neonatal intensive care unit influences maternal milk volume. J. Perinatol. 17:1997;213-217.
62. Hurwitz I., Avnon Y.L., Malkesman O., David A., Weller A. Stress induced responses of infant rats lacking cholecystokinin A (CCKA) receptors. Neural Plast. 8:2001;179. [abstract].
63. Insel T.R., Harbaugh C.R. Central administration of corticotropin releasing factor alters rat pup isolation calls. Pharmacol. Biochem. Behav. 32:1989;197-201.
64. Insel T.R., Winslow J.T. Central administration of oxytocin modulates the infant rat's response to social isolation. Eur. J. Pharmacol. 203:1991;149-152.
65. Jones N.A., Field T., Davalos M., Pickens J. EEG stability in infants/children of depressed mothers. Child Psychiatry Hum. Dev. 28:1997;59-70.
66. Kalin N.H., Shelton S.E., Lynn D.E. Opiate systems in mother and infant primates coordinate intimate contact during reunion. Psychoneuroendocrinology. 20:1995;735-742.
67. Kehoe P., Blass E.M. Central nervous system mediation of positive and negative reinforcement in neonatal albino rats. Dev. Brain Res. 27:1986;69-75.
68. Kehoe P., Blass E.M. Behaviorally functional opioid systems in infant rats. I. Evidence for olfactory and gustatory classical conditioning. Behav. Neurosci. 100:1986;359-367.
69. Kehoe P., Blass E.M. Behaviorally functional opioid systems in infant rats. II. Evidence for pharmacological, physiological and psychological mediation of pain and stress. Behav. Neurosci. 100:1986;624-630.
70. Kehoe P., Blass E.M. Opioid mediation of separation distress in 10-day-old rats: reversal of stress with maternal stimuli. Dev. Psychobiol. 19:1986;385-398.
71. Kehoe P., Boylan C.B. Behavioral effects of kappa-opioid-receptor stimulation on neonatal rats. Behav. Neurosci. 108:1994;418-423.
72. Kehoe P., Callahan M., Daigle A., Mallison K., Brudzynski S. The effect of cholinergic stimulation on rat pupultrasonic vocalizations. Dev. Psychobiol. 38:2001;92-100.
73. Kehoe P., Harris J.C. Ontogeny of noradrenergic effects on ultrasonic vocalizations in rat pups. Behav. Neurosci. 103:1989;1099-1107.
74. Kendrick K.M., Keverne E.B. Effects of intracerebroventricular infusions of naltrexone and phentolamine on central and peripheral oxytocin release and on maternal behaviour induced by vaginocervical stimulation in the ewe. Brain Res. 505:1989;329-332.
75. Kenny J.T., Blass E.M. Suckling as an incentive to instrumental learning in preweanling rats. Science. 196:1977;898-899.
76. Kuhn C.M., Schanberg S.M. Responses to maternal separation: mechanisms and mediators. Int. J. Dev. Neurosci. 16:1998;261-270.
77. Kuhn C.M., Schanberg S.M., Field T., Symansky R., Zimmerman E., Scafidi F.et al. Tactile-kinesthetic stimulation effects on sympathetic and adrenocortical function in preterm infants. J. Pediatr. 119:1991;434-440.
78. Laviola G., Terranova M.L. The developmental psychobiology of behavioral plasticity in mice: the role of social experiences in the family unit. Neurosci. Biobehav. Rev. 23:1998;197-213.
79. Liu D., Diorio J., Tannenbaum B., Caldji C., Francis D., Freedman A.et al. Maternal care, hippocampal glucocorticoid receptors, and hypothalamic-pituitary-adrenal responses to stress. Science. 277:1997;1659-1662.
80. Malkesman O., Avnon Y.L., Hurwitz I., Weller A. Mother-infant interaction in rats lacking the CCKA receptor. Neural Plast. 8:2001;185. [abstract].
81. Martel F.L., Nevison C.M., Simpson M.J.A., Keverne E.B. Effects of opioid receptor blockade on the social behavior of Rhesus monkeys living in large family groups. Dev. Psychobiol. 28:1995;71-84.
82. Meaney M.J. Maternal care, gene expression, and the transmission of individual differences in stress reactivity across generations. Annu. Rev. Neurosci. 24:2001;1161-1192.
83. Meerlo P., Horvath K.M., Nagy G.M., Bohus B., Koolhaas J.M. The influence of postnatal handling on adult neuroendocrine and behavioral stress reactivity. J. Neuroendocrinol. 11:1999;925-933.
84. Mooncey S., Giannakoulopoulos X., Glover V., Acolet D., Modi N. The effect of mother-infant skin-to-skin contact on plasma cortisol and beta-endorphin concentrations in preterm newborns. Inf. Behav. Dev. 20:1998;553-557.
85. Nelson E.E., Panksepp J. Oxytocin mediates acquisition of maternally associated odor preferences in preweanling rat pups. Behav. Neurosci. 110:1996;583-592.
86. Nelson E.E., Panksepp J. Brain substrates of infant-mother attachment: contributions of opioids, oxytocin, and norepinephrine. Neurosci. Biobehav. Rev. 22:1998;437-452.
87. Normansell L., Siviy S., White K., Panksepp J. Naloxone increases social need. Proc. Am. Soc. Neurosci. 8:1982;592.
88. Nowak R. Development of mother discrimination in single and twin-born lambs. Dev. Psychobiol. 22:1990;833-845.
89. Nowak R. Senses involved in the discrimination of Merino ewes at close contact and from a distance by their newborn lambs. Anim. Behav. 42:1991;357-366.
90. Nowak R., Breton G., Mellot E. CCK and development of mother preference in sheep: a neonatal time course study. Peptides. 22:2001;1309-1316.
91. Nowak R., Goursaud A.-P., Lévy F., Orgeur P., Schaal B., Picard M.et al. Cholecystokinin receptors mediate the development of a preference for the mother by newly born lambs. Behav. Neurosci. 111:1997;1375-1382.
92. Nowak R., Lindsay D.R. Discrimination of Merino ewes by their newborn lambs: important for survival? Appl. Anim. Behav. Sci. 34:1992;61-74.
93. Nowak R., Murphy T.M., Lindsay D.R., Alster P., Andersson R., Uvnäs-Moberg K. Development of a preferential relationship with the mother by the newborn lamb: importance of the sucking activity. Physiol. Behav. 62:1997;681-688.
94. Nowak R., Orgeur P., Pikketty V., Alster P., Andersson R., Uvnas-Moberg K. Plasma cholecystokinin concentrations in 3-day-old lambs: effect of the duration of fasting preceding a sucking bout. Reprod. Nutr. Dev. 37:1997;551-558.
95. Nunez J.F., Ferre P., Escorihuela R.M., Tobena A., Fernandez-Teruel A. Effects of postnatal handling of rats on emotional, HPA-axis, and prolactin reactivity to novelty and conflict. Physiol. Behav. 60:1996;1355-1359.
96. Panksepp J. Affective neuroscience. Oxford: Oxford University Press; 1998.
97. Petrov E.S., Varlinskaya E.I., Smotherman W.P. The first suckling episodes in the rat: the role of endogenous activity at mu and kappa opioid receptors. Dev. Psychobiol. 37:2000;129-143.
98. Pickler R.H., Frankel H.B., Walsh K.M., Thompson N.M. Effects of nonnutritive sucking on behavioral organization and feeding performance in preterm infants. Nurs. Res. 45:1996;132-135.
99. Poeggel G., Lange E., Hase C., Metzger M., Gulyaeva N., Braun K. Maternal separation and early social deprivation in Octodon degua: quantitative changes of nicotinamide adenine dinucleotide phosphate-diaphorase-reactive neurons in the prefrontal cortex and nucleus accumbens. Neuroscience. 94:1999;497-504.
100. Porges S.W., Doussard-Roosevelt J.A., Portales A.L., Greenspan S.I. Infant regulation of the vagal "brake" predicts child behavior problems: a psychobiological model of social behavior. Dev. Psychobiol. 29:1996;697-712.
101. Posner M.I., Rothbart M.K. Developing mechanisms of self-regulation. Dev. Psychopathol. 12:2000;427-441.
102. Robinson S.R., Arnold H.M., Spear N.E., Smotherman W.P. Experience with milk and an artificial nipple promotes conditioned opioid activity in the rat fetus. Dev. Psychobiol. 26:1993;375-387.
103. Roth T.L., Sullivan R.M. Endogenous opioids and their role in odor preference acquisition and consolidation following odor-shock conditioning in infant rats. Dev. Psychobiol. 39:2001;188-198.
104. Roth T.L., Sullivan R.M. Consolidation and expression of a shock-induced odor preference in rat pups is facilitated by opioids. Physiol. Behav. 78:2003;135-142.
105. Scafidi F.A., Field T.M., Schanberg S.M., Bauer C.R., Tucci K., Roberts J.et al. Massage stimulates growth in preterm infants: a replication. Inf. Behav. Dev. 13:1990;167-188.
106. Schanberg S.M., Field T.M. Sensory deprivation stress and supplemental stimulation in the rat pup and preterm human neonate. Child Dev. 58:1987;1431-1447.
107. Schore AN. Affect regulation and the origin of the self: the neurobiology of emotional development. Hillsdale, NJ, England: Lawrence Erlbaum; 1994.
108. Schore A.N. The effects of a secure attachment relationship on right brain development, affect regulation and in infant mental health. Infant Mental Health. 22:2000;6-66.
109. Shayit M., Nowak R., Keller M., Weller A. Establishment of a preference by the newborn lamb for its mother: the role of opioids. Behav. Neurosci. 117:2003;446-454.
110. Shayit M., Weller A. Cholecystokinin receptor antagonists increase the rat pup's preference towards maternal-odor and rug texture. Dev. Psychobiol. 38:2001;164-173.
111. Shayit M, Weller A, Goursaud A-P, Schaal B, Uvnas-Moberg K, Nowak R. Development of mother preference by newborn lambs. II. non nutritive sucking, plasma CCK and endogenous opioids. Submitted.
112. Shide D.J., Blass E.M. Opioid-like effects of intraoral infusions of corn oil and polycose on stress reactions in 10-day-old rats. Behav. Neurosci. 103:1989;1168-1175.
113. Shide D.J., Blass E.M. Opioid mediation of odor preferences induced by sugar and fat in 6-day-old rats. Physiol. Behav. 50:1991;961-966.
114. Shoemaker W.J., Kehoe P. The effects of isolation conditions on brain regional enkephalin and beta-endorphin levels and vocalizations in 10-day-old rat pups. Behav. Neurosci. 109:1995;117-122.
115. Smotherman W.P., Simonik D.K., Andersen S.L., Robinson S.R. Mu and kappa opioid systems modulate responses to cutaneous perioral stimulation in the fetal rat. Physiol. Behav. 53:1993;751-756.
116. Sullivan R.M., McGaugh J.L., Leon M. Norepinephrine-induced plasticity and one-trial learning in neonatal rats. Brain Res. Dev. Brain Res. 60:1991;219-228.
117. Sullivan R.M., Wilson D.A., Leon M. Norepinephrine and learning-induced plasticity in infant rat olfactory system. J. Neurosci. 9:1989;3998-4006.
118. Tornhage C.J., Serenius F., Uvnas-Moberg K., Lindberg T. Plasma somatostatin and cholecystokinin levels in preterm infants during kangaroo care with and without nasogastric tube-feeding. J. Pediatr. Endocrinol. Metab. 11:1998;645-651.
119. Tucker D.M., Luu P., Pribram K.H. Social and emotional self-regulation. Ann. N.Y. Acad. Sci. 769:1995;213-239.
120. Uvnas-Moberg K., Marchini G., Winberg J. Plasma cholecystokinin concentrations after breast feeding in healthy 4 day old infants. Arch. Dis. Child. 68:1993;46-48.
121. Weizman R., Lehmann J., Leschiner S., Allmann I., Stoehr T., Heidbreder C.et al. Long-lasting effects of early handling on the peripheral benzodiazepine receptor. Pharmacol. Biochem. Behav. 64:1999;725-729.
122. Weller A. The ontogeny of motivation: hedonic preferences and their biological basis in developing rats. In: Blass EM, editor. Handbook of behavioral neurobiology, vol. 13. New York: Plenum Press; 2001. p. 483-516.
123. Weller A., Blass E.M. Behavioral evidence for cholecystokinin-opiate interactions in neonatal rats. Am. J. Physiol. 255:1988;R901-R907.
124. Weller A., Blass E.M. Cholecystokinin-induced conditioned-odor preference is blocked by the selective antagonist L-364,718. Proc. Am. Soc. Neurosci. 14:1988;199.
125. Weller A., Blass E.M. Cholecystokinin conditioning in rats: ontogenetic determinants. Behav. Neurosci. 104:1990;199-206.
126. A-receptor antagonist administered to the neonate alters mother-infant interactions in the rat. Pharmacol. Biochem. Behav. 59:1998;843-851.
127. Weller A., Gispan I.H. A cholecystokinin receptor antagonist blocks milk-induced but not maternal-contact-induced decrease in ultrasonic vocalization in rat pups. Dev. Psychobiol. 37:2000;35-43.
128. Weller A., Tsitolovskya L., Gispan I.H., Rabinowitz S. Examining the role of cholecystokinin in appetitive learning in the infant rat. Peptides. 22:2001;1317-1323.
129. Winslow J.T., Hearn E.F., Ferguson J., Young L.J., Matzuk M.M., Insel T.R. Infant vocalization, adult aggression, and fear behavior of an oxytocin null-mutant mouse. Horm. Behav. 37:2000;145-155.
130. Wright J.W., Harding J.W. Regulatory role of brain angiotensins in the control of physiological and behavioral responses. Brain Res. 17:1992;227-262.
131. Woodson R., Hamilton C. The effect of nonnutritive sucking on heart rate in preterm infants. Dev. Psychobiol. 21:1988;207-213.