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Five different genes, Eif4a1, Cd68, Supl15h, Sox15 and Fxr2h, are clustered in a 40kb region of mouse chromosome 11
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A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif
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DMRT1 is up-regulated in the gonads during female-to-male sex reversal in ZW chicken embryos
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Autosomal sex reversal and campomelic dysplasia are caused by mutations in and around the SRY-related gene SOX9
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