Single neuron activity in the Drosophila larval CNS detected with calcium indicators

Journal of Neuroscience Methods

Volumn 127, Issue 2, 2003, Pages 167-178

  Macleod, G T ^a   Suster, M L ^b   Charlton, M P ^a   Atwood, H L ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Calcium imaging; CNS activity; Identified neurons; Synaptic activity

Indexed keywords

CALCIUM; DEXTRAN; GREEN FLUORESCENT PROTEIN;

ARTICLE; CALCIUM CELL LEVEL; CENTRAL NERVOUS SYSTEM; DENDRITE; DROSOPHILA; ELECTRIC ACTIVITY; FLUORESCENCE; LARVA; NERVE CELL; NERVE FIBER; NERVE POTENTIAL; NONHUMAN; PERIKARYON; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENSORY NERVE; SYNAPTIC TRANSMISSION;

EID: 0042668309     PISSN: 01650270     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-0270(03)00127-4     Document Type: Article

References (55)

1. Aberle H., Haghighi A.P., Fetter R.D., McCabe B.D., Magalhães T.R., Goodman C.S. Wishful thinking encodes a BMP type II receptor that regulates synaptic growth in Drosophila. Neuron. 33:2002;545-558.
2. Auld V.J., Fetter R.D., Broadie K., Goodman C.S. Gliotactin, a novel transmembrane protein on peripheral glia is required to form the blood-nerve barrier in Drosophila. Cell. 81:1995;757-767.
3. Baines R.A., Bate M. Electrophysiological development of central neurons in the Drosophila embryo. J. Neurosci. 18:1998;4673-4683.
4. Baines R.A., Robinson S.G., Fujioka M., Jaynes J.B., Bate M. Postsynaptic expression of tetanus toxin light chain blocks synaptogenesis in Drosophila. Curr. Biol. 9:1999;1267-1270.
5. Baines R.A., Seugnet L., Thompson A., Salvaterra P.M., Bate M. Regulation of synaptic connectivity: levels of Fasciclin II influence synaptic growth in the Drosophila CNS. J. Neurosci. 22:2002;6587-6595.
6. Bittner G.D., Fishman H.M. Axon sealing following injury. Ingoglia N.A., Murray M. Axonal Regeneration in the Central Nervous System. 2000;337-370 Marcel Dekker, New York.
7. Bodenstein D. The postembryonic development of Drosophila. Demerec M. Biology of Drosophila. 1965;275-367 Hafner Publishing Company, New York.
8. Bonnot A., Whelan P.J., Mentis G.Z., O'Donovan M.J. Spatiotemporal patterns of motoneuron activation in the rostral lumbar and the sacral segments during locomotor-like activity in the neonatal mouse spinal cord. J. Neurosci. 22:(C203):2002;1-6.
9. Broadie K.S. Functional assays of the peripheral and central nervous systems. Sullivan W., Ashburner M., Hawley R.S. Drosophila Protocols. 2000;296-311 Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
10. Broadus J., Skeath J.B., Spana E.P., Bossing T., Technau G., Doe C.Q. New neuroblast markers and the origin of the aCC/pCC neurons in the Drosophila central nervous system. Mech. Dev. 53:1995;393-402.
11. Burrows M., Pflüger H.J. Positive feedback loops from proprioceptors involved in leg movements of the locust. J. Comp. Physiol. A. 163:1988;425-440.
12. Consoulas C., Restifo L.L., Levine R.B. Dendritic remodeling and growth of motoneurons during metamorphosis of Drosophila melanogaster. J. Neurosci. 22:2002;4906-4917.
13. Curtis N.J., Ringo J.M., Dowse H.B. Morphology of the pupal heart, adult heart, and associated tissues in the fruit fly, Drosophila melanogaster. J. Morphol. 240:1999;225-235.
14. Eddleman C.S., Bittner G.D., Fishman H.M. Barrier permeability at cut axonal ends progressively decreases until an ionic seal is formed. Biophys. J. 79:2000;1883-1890.
15. Engert F., Bonhoeffer T. Dendritic spine changes associated with hippocampal long-term synaptic plasticity. Nature. 399:1999;66-70.
16. Featherstone D.E., Broadie K. Surprises from Drosophila: genetic mechanisms of synaptic development and plasticity. Brain Res. Bull. 53:2000;501-511.
17. Fetcho J.R., Cox K.J.A., O'Malley D.M. Monitoring activity in neuronal populations with single-cell resolution in a behaving vertebrate. Histochem. J. 30:1998;153-167.
18. Gao F.B., Brenman J.E., Jan L.Y., Jan Y.N. Genes regulating dendritic outgrowth, branching, and routing in Drosophila. Genes Dev. 13:1999;2549-2561.
19. Goodman C.S., Doe C.Q. Embryonic development of Drosophila central nervous system. Bate M., Martinez-Arias A. The development of Drosophila melanogaster. 1993;1131-1206 Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
20. Gorczyca M.G., Phillis R.W., Budnik V. The role of tinman, a mesodermal cell fate gene, in axon pathfinding during the development of the transverse nerve in Drosophila. Development. 120:1994;2143-2152.
21. Hoang B., Chiba A. Single-cell analysis of Drosophila larval neuromuscular synapses. Dev. Biol. 229:2001;55-70.
22. Hoyle G., Burrows M. Neural mechanisms underlying behavior in the locust Schistocerca gregaria. II. Integrative activity in metathoracic neurons. J. Neurobiol. 4:1973;43-67.
23. Ikeda K., Koenig J.H. Morphological identification of the motor neurons innervating the dorsal longitudinal flight muscles of Drosophila melanogaster. J. Comp. Neurol. 273:1988;436-444.
24. Jan L.Y., Jan Y.N. Properties of the larval neuromuscular junction in Drosophila melanogaster. J. Physiol. 262:1976;189-214.
25. Karunanithi S., Georgiou J., Charlton M.P., Atwood H.L. Imaging of calcium in Drosophila larval motor nerve terminals. J. Neurophysiol. 78:1997;3465-3467.
26. Kerr R., Lev-Ram V., Baird G., Vincent P., Tsien R.Y., Schafer W.R. Optical imaging of calcium transients in neurons and pharyngeal muscle of C. elegans. Neuron. 26:2000;583-594.
27. Kitamoto T. Conditional modification of behavior in Drosophila by targeted expression of a temperature-sensitive shibire allele in defined neurons. J. Neurobiol. 47:2001;81-92.
28. Kreitzer A.C., Gee K.R., Archer E.A., Regehr W.G. Monitoring presynaptic calcium dynamics in projection fibers by in vivo loading of a novel calcium indicator. Neuron. 27:2000;25-32.
29. Landgraf M., Bossing T., Technau G.M., Bate M. The origin, location, and projections of the embryonic abdominal motorneurons of Drosophila. J. Neurosci. 17:1997;9642-9655.
30. Macleod G.T., Hegstöm-Wojtowicz M., Charlton M.P., Atwood H.L. Fast calcium signals in Drosophila motor neuron terminals. J. Neurophysiol. 88:2002;2659-2663.
31. Marder E., Bucher D. Central pattern generators and the control of rhythmic movements. Curr. Biol. 11:2001;R986-R996.
32. Merritt D.J., Whitington P.M. Central projections of sensory neurons in the Drosophila embryo correlate with sensory modality, soma position, and proneural gene function. J. Neurosci. 15:1995;1755-1767.
33. Nelson J.C., Wyman R.J. Examination of paralysis in Drosophila temperature-sensitive paralytic mutations affecting sodium channels: a proposed mechanism of paralysis. J. Neurobiol. 21:1990;453-469.
34. O'Donovan M.J., Ho S., Sholomenko G., Yee W. Real-time imaging of neurons retrogradely and anterogradely labelled with calcium-sensitive dyes. J. Neurosci. Meth. 46:1993;91-106.
35. Ogawa H., Baba Y., Oka K. Direction of action potential propagation influences calcium increases in distal dendrites of the cricket giant interneurons. J. Neurobiol. 53:2002;44-56.
36. O'Malley D.M., Kao Y.H., Fetcho J.R. Imaging the functional organization of zebrafish hindbrain segments during escape behaviors. Neuron. 17:1996;1145-1155.
37. Phelan P., Nakagawa M., Wilkin M.B., Moffat K.G., O'Kane C.J., Davies J.A., Bacon J.P. Mutations in shaking-B prevent electrical synapse formation in the Drosophila giant fiber system. J. Neurosci. 16:1996;1101-1113.
38. Pierce V.A., Mueller L.D., Gibbs A.G. Osmoregulation in Drosophila melanogaster selected for urea tolerance. J. Exp. Biol. 202:1999;2349-2358.
39. Reiter L.T., Potocki L., Chien S., Gribskov M., Bier E. A systematic analysis of human disease-associated gene sequences in Drosophila melanogaster. Genome Res. 11:2001;1114-1125.
40. Rohrbough J., Broadie K. Electrophysiological analysis of synaptic transmission in central neurons of Drosophila larvae. J. Neurophysiol. 88:2002;847-860.
41. Rohrbough J., O'Dowd D.K., Baines R.A., Broadie K. Cellular bases of behavioral plasticity: establishing and modifying synaptic circuits in the Drosophila genetic system. J. Neurobiol. 54:2003;254-271.
42. Rosay P., Armstrong J.D., Wang Z., Kaiser K. Synchronized neural activity in the Drosophila memory centers and its modulation by amnesiac. Neuron. 30:2001;759-770.
43. Sabatini B.L., Svoboda K. Analysis of calcium channels in single spines using optical fluctuation analysis. Nature. 408:2000;589-593.
44. 2+ ions in dendritic spines. Neuron. 33:2002;439-452.
45. Sachse S., Galizia G. Role of inhibition for temporal and spatial odor representation in olfactory output neurons: a calcium imaging study. J. Neurophysiol. 87:2002;1106-1117.
46. Schrader S., Merritt D.J. Central projections of Drosophila sensory neurons in the transition from embryo to larva. J. Comp. Neurol. 425:2000;34-44.
47. Sink H., Whitington P.M. Pathfinding in the central nervous system and periphery by identified embryonic Drosophila motor axons. Development. 112:1991;307-316.
48. Suster M.L., Martin J.-R., Sung C., Robinow S. Targeted expression of tetanus toxin reveals sets of neurons involved in larval locomotion in Drosophila. J. Neurobiol. 55:2003;233-246.
49. Sweeney S.T., Broadie K., Keane J., Niemann H., O'Kane C.J. Targeted expression of tetanus toxin light chain in Drosophila specifically eliminates synaptic transmission and causes behavioral defects. Neuron. 14:1995;341-351.
50. Takahashi M., Narushima M., Oda Y. In vivo imaging of functional inhibitory networks on the Mauthner cell of larval zebrafish. J. Neurosci. 22:2002;3929-3938.
51. Trimarchi J.R., Schneiderman A.M. The motor neurons innervating the direct flight muscles of Drosophila melanogaster are morphologically specialized. J. Comp. Neurol. 340:1994;427-443.
52. Trimarchi J.R., Ping J., Murphey R.K. Controlling the motor neuron. Budnick V., Gramates L.S. Neuromuscular Junctions in Drosophila: International Review of Neurobiology. 43:1999;241-264.
53. Umbach J.A., Saitoe M., Kidokoro Y., Gundersen C.B. Attenuated influx of calcium ions at nerve endings of csp and shibire mutant Drosophila. J. Neurosci. 18:1998;3233-3240.
54. Wang J.W., Wong A.M., Flores J., Vosshall L.B., Axel R. Two-photon calcium imaging reveals an odor-evoked map of activity in the fly brain. Cell. 112:2003;271-282.
55. White B.H., Osterwalder T.P., Yoon K.S., Joiner W.J., Whim M.D., Kaczmarek L.K., Keshishian H. Targeted attenuation of electrical activity in Drosophila using a genetically modified K(+) channel. Neuron. 31:2001;699-711.