Effects of lipopolysaccharide on vascular reactivity and mortality in rats

Autonomic and Autacoid Pharmacology

Volumn 22, Issue 5-6, 2002, Pages 247-252

  Nunes, J P L ^a  

^a University of Porto   (Portugal)

Author keywords

Corticosterone; Lipopolysaccharide; Mortality; Rat aorta; SHR

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CORTICOSTERONE; NORADRENALIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA CONSTRICTION; ARTICLE; BLOOD VESSEL REACTIVITY; BLOOD VESSEL TONE; CHRONIC DISEASE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG SENSITIVITY; HYPERTENSION; MALE; MORTALITY; MUSCLE FIBRIL; NONHUMAN; RAT; RAT STRAIN; SPONTANEOUSLY HYPERTENSIVE RAT; STRAIN DIFFERENCE; VASCULAR RING; VASCULAR SMOOTH MUSCLE;

ANIMALS; AORTA, THORACIC; BLOOD PRESSURE; CORTICOSTERONE; HYPERTENSION; INJECTIONS, INTRAPERITONEAL; LIPOPOLYSACCHARIDES; MALE; MUSCLE CONTRACTION; MUSCLE, SMOOTH, VASCULAR; RATS; RATS, INBRED SHR; RATS, INBRED WKY; RATS, WISTAR;

EID: 0042624729     PISSN: 14748665     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1474-8673.2002.00270.x     Document Type: Article

References (17)

1. BATTISTELLA-PATTERSON, A.S., WANG, S. & WRIGHT, G.L. (1997). Effect of disruption of the cytoskeleton on smooth muscle contraction. Can. J. Physiol. Pharmacol., 75, 1287-1299.
2. BERNARD, C., MERVAL, R., ESPOSITO, B. & TEDGUI, A. (1998). Resistance to endotoxin shock in spontaneously hypertensive rats. Hypertension, 31, 1350-1356.
3. EROL, A. & KOSAY, S. (2000). Effects of aminoguanidine administration on vascular hyporeactivity in thoracic aorta from endotoxaemic rats. Eur. J. Pharmacol., 408, 175-181.
4. BERNER, P.F., SOMLYO, A.V. & SOMLYO, A.P. (1981). Hypertrophy-induced increase of intermediate filaments in vascular smooth muscle. J. Cell Biol., 88, 96-100.
5. FOLKOW, B. (1982). Physiological aspects of primary hypertension. Physiol. Rev., 62, 347-504.
6. GAVRAS, H., BRUNNER, H.R., LARAGH, J.H., VAUGHAN, E.D., KOSS, M., COTE, L.J. & GAVRAS, I. (1975). Malignant hypertension resulting from deoxycorticosterone acetate and salt excess: role of renin and sodium in vascular changes. Circ. Res., 36, 300-309.
7. HERLIHY, J.T. & MURPHY, R.A. (1973). Length-tension relationship of smooth muscle of the hog carotid artery. Circ. Res., 33, 275-283.
8. LANDRY, D.W. & OLIVER, JA. (2001). The pathogenesis of vasodilatory shock. N. Engl. J. Med., 345, 588-595.
9. LOU, Y.K., WEN, C., LI, M., ADAMS, D.J., WANG, M.X., YANG, F., MORRIS, B.J & WHITWORTH, J.A. (2001). Decreased renal expression of nitric oxide synthase isoforms in adrenocorticotropin-induced and corticosterone-induced hypertension. Hypertension, 37, 1164-1170.
10. MURPHY, R.A. (1976). Contractile system function in mammalian smooth muscle. Blood Vessels, 13, 1-23.
11. NUNES, J.P.L. (2002). Cytoskeleton, passive tension and the contraction of the rat aorta to phorbol 12,13-dibuty-rate. Pharmacol. Res., 46, 113-117.
12. NUNES, J.P. & GUIMARÃES, S. (1997). The influence of tone and pertussis toxin on the responses of the canine saphenous vein to phenylephrine, UK-14,304 and chloroethylclonidine. Pharmacol. Rev. Commun., 9, 41-48.
13. NUNES, J.P. & GUIMARÃES, S. (1999). The influence of the wall tension on the contractile responses of arteries. Fundam. Clin. Pharmacol., 13, 193-197.
14. NUNES, J.P.L. & GUIMARÃES, S. (2000). Wall tension and contraction of the aorta in 6-months-old spontaneously hypertensive rats. J. Auton. Pharmacol., 20, 265-269.
15. SHAN, Q. & BOURREAU, J.P. (2000). Cardiac and vascular effects of nitric oxide synthase inhibition in lipopolysaccharide-treated rats. Eur. J. Pharmacol., 406, 257-264.
16. SOMLYO, A.P. & SOMLYO, A.V. (1994). Signal transduction and regulation in smooth muscle. Nature, 372, 231-236.
17. TRENDELENBURG, U. (1966). Mechanisms of supersensitivity and subsensitivity to sympathomimetic amines. Pharmacol. Rev., 18, 629-640.