Cytoskeleton, passive tension and the contraction of the rat aorta to phorbol 12,13-dibutyrate

Pharmacological Research

Volumn 46, Issue 2, 2002, Pages 113-117

  Nunes, José Pedro L ^a  

^a University of Porto   (Portugal)

Author keywords

Colchicine; Cytochalasin B; Phorbol 12,13 dibutyrate; Rat aorta; SHR; Wall tension

Indexed keywords

ACTIN; COCAINE; COLCHICINE; CYTOCHALASIN B; NORADRENALIN; PHORBOL DIBUTYRATE; TUBULIN;

ACTIN POLYMERIZATION; ANIMAL TISSUE; AORTA CONSTRICTION; ARTICLE; BODY WEIGHT; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSKELETON; DIASTOLIC BLOOD PRESSURE; DRUG EFFECT; DRUG MECHANISM; HEART WEIGHT; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RAT; RAT STRAIN; SMOOTH MUSCLE TONE; STRAIN DIFFERENCE; SYSTOLIC BLOOD PRESSURE; THORACIC AORTA; VASCULAR RING;

EID: 0036417295     PISSN: 10436618     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1043-6618(02)00087-7     Document Type: Article

References (21)

1. Herlihy JT, Murphy RA. Length-tension relationship of smooth muscle of the hog carotid artery. Circ Res 1973; 33: 275-83.
2. Murphy RA. Contractile system function in mammalian smooth muscle. Blood Vessels 1976; 13: 1-23.
3. Battistella-Patterson AS, Wang S, Wright GL. Effect of disruption of the cytoskeleton on smooth muscle contraction. Can J Physiol Pharmacol 1997; 75: 1287-99.
4. Nunes JP, Guimarães S. The influence of tone and pertussis toxin on the responses of the canine saphenous vein to phenylephrine, UK-14,304 and chloroethylclonidine. Pharmacol Rev Commun 1997; 9: 41-8.
5. Nunes JP, Guimarães S. The influence of the wall tension on the contractile responses of arteries. Fundam Clin Pharmacol 1999; 13: 193-7.
6. Nunes JPL, Guimarães S. Wall tension and contraction of the aorta in 6 months old spontaneously hypertensive rats. J Autonom Pharmacol 2000; 20: 265-9.
7. Trendelenburg U. Mechanisms of supersensitivity and subsensitivity to sympathomimetic amines. Pharmacol Rev 1966; 18: 629-40.
8. Coskinas E, Price JM. Length-dependent sensitivity of vascular smooth muscle in normotensive and hypertensive animals. Am J Physiol 1987; 253: H402-11.
9. 2+ utilization in the constriction of rat aorta to stimulation of protein kinase C by phorbol dibutyrate. J Pharmacol Exp Ther 1987; 242: 934-9.
10. Jiang MJ, Morgan KG. Intracellular calcium levels in phorbol ester-induced contractions of vascular muscle. Am J Physiol 1987; 253: H1365-71.
11. Jiang MJ, Morgan KG. Agonist-specific myosin phosphorylation and intracellular calcium during isometric contractions of arterial smooth muscle. Pflugers Arch 1989; 413: 637-43.
12. Bilder GE, Kasiewski CJ, Perrone MH. Phorbol-12,13-dibutyrate-induced vasoconstriction in vivo: Characterization of response in genetic hypertension. J Pharmacol Exp Ther 1990; 252: 526-30.
13. Somlyo AP, Somlyo AV. Signal transduction and regulation in smooth muscle. Nature 1994; 372: 231-6.
14. Shibata S, Kurahashi K, Kichii M. A possible etiology of contractility impairment of vascular smooth muscle from spontaneously hypertensive rats. J Pharmacol Exp Ther 1973; 185: 406-17.
15. Clineschmidt BV, Geller RG, Govier WC, Sjoerdsma A. Reactivity to norepinephrine and nature of the alpha adrenergic receptor in vascular smooth muscle of a genetically hypertensive rat. Eur J Pharmacol 1970; 10: 45-50.
16. Wright G, Hurn E. Cytochalasin inhibition of slow tension increase in rat aortic rings. Am J Physiol 1994; 267: H1437-46.
17. Murphy RA. What is special about smooth muscle? The significance of covalent crossbridge regulation. FASEB J 1994; 8: 311-8.
18. Fultz ME, Li C, Geng W, Wright GL. Remodeling of the actin cytoskeleton in the contracting A7r5 smooth muscle cell. J Muscle Res Cell Motility 2000; 21: 775-87.
19. Andreu JM, Timasheff SN. Tubulin bound to colchicine forms polymers different from microtubules. Proc Natl Acad Sci USA 1982; 79: 6753-6.
20. Platts SH, Falcone JC, Holton WT, Hill MA, Meininger GA. Alteration of microtubule polymerization modulates arteriolar vasomotor tone. Am J Physiol 1999; 277: H100-6.
21. Battistella-Patterson AS, Fultz ME, Li C, Geng W, Norton M, Wright GL. PKC alpha translocation is microtubule-dependent in passaged smooth muscle cells. Acta Physiol Scand 2000; 170: 87-97.