Strategies for the synthesis of N-(azacycloalkyl)bisindolylmaleimides: Selective inhibitors of PKCβ

Tetrahedron

Volumn 59, Issue 36, 2003, Pages 7215-7229

  Faul, Margaret M ^a   Grutsch, John L ^a   Kobierski, Michael E ^a   Kopach, Michael E ^a   Krumrich, Christine A ^a   Staszak, Michael A ^a   Udodong, Uko ^a   Vicenzi, Jeffrey T ^a   Sullivan, Kevin A ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

Angiogenesis; N (azacycloalkyl)bisindolylmaleimides; Vascular endothelial growth factor

Indexed keywords

3 (1 METHYL 1H INDOL 3 YL) 4 [1 [1 (2 PYRIDINYLMETHYL) 4 PIPERIDINYL] 1H INDOL 3 YL] 1H PYRROLE 2,5 DIONE; ENZASTAURIN; MALEIMIDE DERIVATIVE; PROTEIN KINASE C BETA; PROTEIN KINASE C INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; DRUG IDENTIFICATION; DRUG SYNTHESIS; MEDICAL ASSESSMENT; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

EID: 0042521246     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4020(03)00973-6     Document Type: Article

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