Lipid-binding proteins: Structure of the phospholipid ligands

Protein Science

Volumn 12, Issue 9, 2003, Pages 2109-2117

  Marsh, Derek ^a  

^a MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

Author keywords

Lipase; Permeability increasing protein; Phospholipase; Phospholipid transfer protein; Saposin; Ultraspiracle protein

Indexed keywords

CARBOXYLESTERASE; ESTER; GLYCEROL; HYDROCARBON; LIGAND; LIPID; LIPID BINDING PROTEIN; PHOSPHODIESTER; PHOSPHOLIPASE; PHOSPHOLIPID; PHOSPHOLIPID TRANSFER PROTEIN; SPHINGOLIPID ACTIVATOR PROTEIN; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG;

ARTICLE; BILAYER MEMBRANE; CELL HETEROGENEITY; CRYSTAL STRUCTURE; ENANTIOMER; LIGAND BINDING; LIPID ANALYSIS; MEMBRANE STRUCTURE; NONHUMAN; ORIENTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DATABASE; PROTEIN STRUCTURE; STEREOCHEMISTRY; STRUCTURE ANALYSIS;

ANIMALS; CARRIER PROTEINS; CELL MEMBRANE; DATABASES; DNA-BINDING PROTEINS; FATTY ACID-BINDING PROTEINS; GLYCEROL; GLYCOPROTEINS; HUMANS; LIGANDS; LIPID BILAYERS; LIPIDS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR CONFORMATION; PHOSPHOLIPASES A; PHOSPHOLIPIDS; PROTEIN BINDING; PROTEIN CONFORMATION; SPHINGOLIPID ACTIVATOR PROTEINS; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEINS;

EID: 0042510861     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.0396803     Document Type: Article

References (28)

1. Ahn, V.E., Faull, K.F., Whitelegge, J.P., Fluharty, A.L., and Prive, G.G. 2003. Crystal structure of saposin B reveals a dimeric shell for lipid binding. Proc. Natl. Acad. Sci. 100: 38-43.
2. Billas, I.M.L., Moulinier, L., Rochel, N., and Moras, D. 2001. Crystal structure of the ligand-binding domain of the ultraspiracle protein USP, the ortholog of retinoid X receptors in insects. J. Biol. Chem. 276: 7465-7474.
3. Brzozowski, A.M., Savage, H., Verma, C.S., Turkenburg, J.P., Lawson, D.M., Svendsen, A., and Patkar, S. 2000. Structural origins of the interfacial activation in Thermomyces (Humicola) lanuginosa lipase. Biochemistry 39: 15071-15082.
4. Cevc, G. and Marsh, D. 1987. Phospholipid bilayers. Physical principles and models. Wiley- Interscience, New York.
5. Elder, M., Hitchcock, M.P., Mason, R., and Shipley, G.G. 1977. A refinement analysis of the crystallography of the phospholipid, 1,2-dilauroyl-DL-phosphatidylethanolamine, and some remarks on lipid-lipid and lipid-protein interactions. Proc. R. Soc. Lond. A 354: 157-170.
6. Gorenstein, D.G., Kar, D., Luxon, B.A., and Momii, R.K. 1976. Conformational study of cyclic and acyclic phosphate esters. CNDO/2 calculations of angle strain and torsional strain. J. Am. Chem. Soc. 98: 1668-1673.
7. Hurley, J.H., Tsujishita, Y., and Pearson, M.A. 2000. Floundering about at cell membranes: A structural view of phospholipid signaling. Curr. Opin. Struct. Biol. 10: 737-743.
8. Kleiger, G., Beamer, L.J., Grothe, R., Mallick, P., and Eisenberg, D. 2000. The 1.7 Å crystal structure of BPI: A study of how two dissimilar amino acid sequences can adopt the same fold. J. Mol. Biol. 299: 1019-1034.
9. Moser, M., Marsh, D., Meier, P., Wassmer, K.-H., and Kothe, G. 1989. Chain configuration and flexibility gradient in phospholipid membranes. Comparison between spin-label electron spin resonance and deuteron nuclear magnetic resonance, and identification of new conformations. Biophys. J. 55: 111-123.
10. Oganesyan, V., Oganesyan, N., Terzyan, S., Qu, D.F., Dauter, Z., Esmon, N.L., and Esmon, C.T. 2002. The crystal structure of the endothelial protein C receptor and a bound phospholipid. J. Biol. Chem. 277: 24851-24854.
11. Oh. B.-H. 1995. A probe molecule composed of seventeen percent of total diffracting matter gives correct solutions in molecular replacement. Acta Crystallogr. D 51: 140-144.
12. Ollesch, G., Kaunzinger, A., Juchelka, D., Schuber-Zsilavecz, M., and Ermler, U. 1999. Phospholipid bound to the flavohemoprotein from Alcaligenes eutrophus. Eur. J. Biochem. 262: 396-405.
13. Pascher, I. and Sundell, S. 1992. Molecular arrangements in sphingolipids - Crystal structure of the ceramide N-(2D,3D-dihydroxyoctadecanoyl)-phytosphingosine. Chem. Phys. Lipids 62: 79-86.
14. Pascher, I., Sundell, S., Harlos, K., and Eibl, H. 1987. Conformation and packing properties of membrane lipids: The crystal structure of sodium dimyristoylphosphatidylglycerol. Biochim. Biophys. Acta 896: 77-88.
15. Pascher, I., Lundmark, M., Nyholm, P.-G., and Sundell, S. 1992. Crystal structures of membrane lipids. Biochim. Biophys. Acta 1113: 339-373.
16. Pearson, R.H. and Pascher, I. 1979. The molecular structure of lecithin dihydrate. Nature 281: 499-501.
17. Roderick, S.L., Chan, W.W., Agate, D.S., Olsen, L.R., Vetting, M.W., Rajashankar, K.R., and Cohen, D.E. 2002. Structure of human phosphatidylcholine transfer protein in complex with its ligand. Nat. Struct. Biol. 9: 507-511.
18. 2. Adv. Protein Chem. 45: 53-88.
19. 2 in a complex with a transition-state analogue. Science 250: 1563-1566.
20. 2 from inflammatory exudate. Science 254: 1007-1010.
21. Seelig, J. 1977. Deuterium magnetic resonance: Theory and application to lipid membranes. Q. Rev. Biophys. 10: 358-418.
22. 2 with a transition-state analogue. Acta Crystallogr D 54: 334-341.
23. 2 complexed with a substrate derived inhibitor. Nature 347: 689-691.
24. van Tilbeurgh, H., Egloff, M.P., Martinez, C., Rugani, N., Verger, R., and Cambillau, C. 1993. Interfacial activation of the lipase-procolipase complex by mixed micelles revealed by X-ray crystallography. Nature 362: 814-820.
25. Vetting, M.W. and Ohlendorf, D.H. 2000. The 1.8 Å crystal structure of catechol 1,2-dioxygenase reveals a novel hydrophobic helical zipper as a subunit linker. Struct. Fold. Des. 8: 429-440.
26. Wallace, A.C., Laskowski, R.A., and Thornton, J.M. 1995. LIGPLOT - A program to generate schematic diagrams of protein ligand interactions. Protein Eng. 8: 127-134.
27. 2 in a complex with a transition-state analogue. Science 250: 1560-1563.
28. Yoder, M.D., Thomas, L.M., Tremblay, J.M., Oliver, R.L., Yarbrough, L.R., and Helmkamp Jr., G.M. 2001. Structure of a multifunctional protein. J. Biol. Chem. 276: 9246-9252.