Simultaneous synchrotron radiation X-ray diffraction-DSC analysis of melting and crystallization behavior of trilauroylglycerol in nanoparticles of oil-in-water emulsion

JAOCS, Journal of the American Oil Chemists' Society

Volumn 80, Issue 8, 2003, Pages 731-739

  Higami, M ^a   Ueno, S ^a   Segawa, T ^b   Iwanami, K ^b   Sato, K ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

^b JAPAN FOOD RESEARCH LABORATORIES   (Japan)

Author keywords

Nanoparticles; O W emulsion; Polymorphism; Trilauroylglycerol

Indexed keywords

CRYSTALLIZATION; DIFFERENTIAL SCANNING CALORIMETRY; EMULSIONS; MELTING; NANOSTRUCTURED MATERIALS; SYNCHROTRON RADIATION; X RAY DIFFRACTION;

OIL-IN-WATER EMULSION;

GLYCEROL;

EID: 0042428701     PISSN: 0003021X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11746-003-0765-2     Document Type: Article

References (36)

1. Washington, C., and K. Evans, Release Rate Measurement of Model Hydrophobic Solutes from Submicron Triglyceride Emulsions, J. Controlled Release 35:383-390 (1995).
2. Norden, T.P., B. Siekmann, S. Lundquist, and M. Malmsten, Physicochemical Characterisation of a Drug-Containing Phospholipid-Stabilised O/W Emulsion for Intravenous Administration, Eur. J. Pharm. Sci. 13:393-401 (2001).
3. Bunjes, H., B. Siekmann, and K. Westesen, Emulsions of Supercooled Melts - A Novel Drug Delivery System, Submicron Emulsions in Drug Targeting and Delivery, edited by S. Benita, Harwood Academic Publishers, Singapore, 1998, pp. 175-204.
4. Vringer, T., and H.A.G. de Ronde, Preparation and Structure of a Water-in-Oil Cream Containing Lipid Nanoparticles, J. Pharm. Sci. 84:466-472 (1995).
5. Siekmann, B., and K. Westesen, Investigations on Solid Lipid Nanoparticles Prepared by Precipitation in O/W Emulsions, Eur. J. Pharm. Biopharm. 43:104-109 (1996).
6. Freitas, C., and R.H. Muller, Correlation Between Long-term Stability of Solid Lipid Nanoparticles (SLN™) and Crystallinity of the Lipid Phase, Ibid. 47:125-132 (1999).
7. Dingier, H., R.P. Blum, H. Niehus, R.H. Muller, and S. Gohla, Solid Lipid Nanoparticles (SLN™/LipopearlsTM) - A Pharmaceutical and Cosmetic Carrier for the Application of Vitamin E in Dermal Products, J. Microencapsul. 16:751-767 (1999).
8. Jenning, V., M. Schäfer-Korting, and S. Gohla, Vitamin A-Loaded Solid Lipid Nanoparticles for Topical Use: Drug Release Properties, J. Controlled Release 66:115-126 (2000).
9. Muller, R.H., K. Mader, and S. Gohla, Solid Lipid Nanoparticles (SLN) for Controlled Drug Delivery - A Review of the State of the Art, Eur. J. Pharm. Biopharm. 50:161-177 (2000).
10. Jenning, V., A.F. Thunemann, and S.H. Gohla, Characterisation of a Novel Solid Lipid Nanoparticle Carrier System Based on Binary Mixtures of Liquid and Solid Lipids, Int. J. Pharm. 199: 167-177 (2000).
11. Mehnert, W., and K. Mader, Solid Lipid Nanoparticles Production, Characterization and Applications, Adv. Drug Deliv. Rev. 47:165-196 (2001).
12. Bunjes, H., K. Westesen, and M.H.J. Koch, Crystallization Tendency and Polymorphic Transitions in Triglyceride Nanoparticles, Int. J. Pharm. 129:159-173 (1996).
13. Siekmann, B., and K. Westesen, Thermoanalysis of the Recrystallization Process of Melt-Homogenized Glyceride Nanoparticles, Colloid. Surf. B 3:159-175 (1994).
14. Westesen, K., and B. Siekmann, Investigation of the Gel Formation of Phospholipid-Stabilized Solid Lipid Nanoparticles, Int. J. Pharm. 151:35-45 (1997).
15. Freitas, C., and R.H. Muller, Effect of Light and Temperature on Zeta Potential and Physical Stability in Solid Lipid Nanoparticle (SLN™) Dispersions, Ibid. 168:221-229 (1998).
16. 1H-NMR Study, Ibid. 205:15-21 (2000).
17. Westesen, K., B. Siekmann, and M.H.J. Koch, Investigations on the Physical State of Lipid Nanoparticles by Synchrotron Radiation X-ray Diffraction, Ibid. 93:189-199 (1993).
18. Unruh, T., H. Bunjes, K. Westesen, and M.H.J. Koch, Observation of Size-Dependent Melting in Lipid Nanoparticles, J. Phys. Chem. B 1035: 10373-10377 (1999).
19. Bunjes, H., M.H.J. Koch, and K. Westesen, Effect of Particle Size on Colloidal Solid Triglycerides, Langmuir 16:5234-5241 (2000).
20. Unruh, T., H. Bunjes, K. Westesen, and M.H.J. Koch, Investigations on the Melting Behavior of Triacylglyceride Nanoparticles, Colloid Polym. Sci. 279:398-403 (2001).
21. Bunjes, H., and K. Westesen, Influences of Colloidal State on Physical Properties of Solid Fats, in Crystallization Processes in Fats and Lipid Systems, edited by N. Garti and K. Sato, Marcel Dekker, New York, 2001, pp. 457-483.
22. Unruh, T., K. Westesen, P. Boecke, P. Lindner, and M.H.J. Koch, Self-Assembly of Triglyceride Nanoparticles in Suspension, Langmuir 18: 1796-1800 (2002).
23. Minato, A., S. Ueno, K. Smith, Y. Amemiya, and K. Sato, Thermodynamic and Kinetic Study on Phase Behavior of Binary Mixtures of POP and PPO Forming Molecular Compound Systems, J. Phys. Chem. 101:3498-3505 (1997).
24. Takeuchi, M., S. Ueno, J. Yano, E. Floter, and K. Sato, Polymorphic Transformation of 1,3-Distearoyl-sn-linoleoyl-glycerol, J. Am. Oil Chem. Soc. 77:1243-1249 (2000).
25. Lopez, C., P. Leieur, G. Keller, and M. Ollivon, Crystallization in Emulsion: Application to Thermal and Structural Behavior of Milk Fat, in Crystallization and Solidification Properties of Lipids, edited by N. Widlak, R.W. Hartel, and S.S. Narine, AOCS Press, Champaign, 2001, pp. 190-199.
26. Takeuchi, M., S. Ueno, E. Flöter, and K. Sato, Binary Phase Behavior of 1,3-Distearoyl-sn-oleoylglycerol (SOS) and 1,3-Distearoyl-sn-linoleoylglycerol (SLS), J. Am. Oil Chem. Soc. 79: 627-632.
27. Lopez, C., P. Leieur, G. Keller, and M. Ollivon, Thermal and Structural Behavior of Milk Fat: 1 Unstable Species of Cream, J. Colloid Interface Sci. 229:62-71 (2000).
28. Lopez, C., P. Leieur, C. Bourgaux, G. Keller, and M. Ollivon, Thermal and Structural Behavior of Milk Fat: 2 Crystalline Forms Obtained by Slow Cooling of Cream, Ibid. 240:150-161 (2001).
29. Lopez, C., A. Riaublanc, P. Leieur, C. Bourgaux, G. Keller, and M. Ollivon, Definition of a Model Fat for Crystallization-in-Emulsion Studies, J. Am. Oil Chem. Soc. 78:1233-1244 (2001).
30. Coupland, J., E. Dickinson, D.J. McClements, M. Povey, and C.R. Mimmerand, Crystallization in Simple Paraffins and Monoacid Saturated Triacylglycerols Dispersed in Water, in Food Colloids and Polymers: Stability and Mechanical Properties, edited by E. Dickinson and P. Walstra, The Royal Society of Chemistry, Cambridge, 1993, pp. 243-249.
31. Povey, M.J.W., Crystallization of Oil-in-Water Emulsions, in Crystallization Processes in Fats and Lipid Systems, edited by N. Garti and K. Sato, Marcel Dekker, New York, 2001, pp. 251-288.
32. Awad, T.S., Y. Hamada, and K. Sato, Effects of Addition of Diacylglycerols on Fat Crystallization in Oil-in-Water Emulsion, Eur. J. Lipid Sci. Technol. 103:734-741 (2001).
33. Katsuragi, T., N. Kaneko, and K. Sato, Effects of Addition of Hydrophobic Sucrose Fatty Acid Oligoesters on Crystallization Rates of n-Hexadecane in Oil-in-Water Emulsions, Colloid Surf. B 20:229-237 (2001).
34. Hamada, Y., I. Kobayashi, M. Nakajima, and K. Sato, Optical and Interfacial Tension Study of Crystallization of n-Alkane in Oil-in-Water Using Mono-dispersed Droplets, Crystal Growth Design 2:579-584 (2002).
35. Aquilano, D., and G. Squaldino, Fundamental Aspects of Equilibrium and Crystallization Kinetics, in Crystallization Processes in Fats and Lipid Systems, edited by N. Garti and K. Sato, Marcel Dekker, New York, 2001, pp. 1-51.
36. Flack, E., Butter, Margarine, Spread and Baking Fats, in Lipid Technologies and Applications, edited by F.D. Gunstone and F.B. Padley, Marcel Dekker, New York, 1997, pp. 305-327.