Use of recombinant factor VIIa for bleeding in children with Glanzmann thrombasthenia

Pediatric Hematology and Oncology

Volumn 20, Issue 6, 2003, Pages 435-438

  Çaǧlar, Kudret ^a   Çetinkaya, Ahmet ^a   Aytaç, Selin ^a   Gümrük, Fatma ^a   Gürgey, Aytemiz ^a  

^a HACETTEPE UNIVERSITY   (Turkey)

Author keywords

Children; Glanzmann thrombastenia; Recombinant factor VIIa

Indexed keywords

ADENOSINE DIPHOSPHATE; ADRENALIN; COLLAGEN; RECOMBINANT BLOOD CLOTTING FACTOR 7A; SPONGOSTAN; THROMBOCYTE CONCENTRATE;

ARTICLE; BLEEDING TIME; CLINICAL ARTICLE; CLINICAL FEATURE; DISEASE COURSE; DRUG EFFECT; FEMALE; GLANZMANN DISEASE; HUMAN; INFANT; MALE; PLASMAPHERESIS; PRESCHOOL CHILD; SUBSTITUTION THERAPY; THROMBOCYTE ADHESION; THROMBOCYTE AGGREGATION; THROMBOCYTE TRANSFUSION; TREATMENT OUTCOME;

EID: 0042427773     PISSN: 08880018     EISSN: None     Source Type: Journal    
DOI: 10.1080/08880010390220135     Document Type: Article

References (9)

1. Tengborn L, Petruson B. A patient with Glanzmann thrombasthenia and epistaxis successfully treated with recombinant factor VIIa. Thromb Haemost. 1996;75:981-982.
2. d'Oiron R, Menart C, Trzeciak MC, et al. Use of recombinant factor VIIa in 3 patients with inherited type I Glanzmann's thrombasthenia undergoing invasive procedures. Thromb Haemost. 2000;83:644-647.
3. Chuansumrit A, Sangkapreecha C, Hathirat P. Successful epistaxis control in a patient with Glanzmann thrombasthenia by increased bolus injection dose of recombinant factor VIIa. Thromb Haemost. 1999;82:1778.
4. Aledort LM. Recombinant factor VIIa is a pan-hemostatic agent? Thromb Haemost. 2000;83:637-638.
5. Poon MC, Demers C, Jobin F, Wu JW. Recombinant factor VIIa is effective for bleeding and surgery in patients with Glanzmann thrombasthenia. Blood. 1999;94:3951-3953.
6. Patel RK, Savidge GF, Rangarajan S. Use of recombinant factor VIIa for postoperative haemorrhage in a patient with Glanzmann's thrombasthenia and human leucocyte antigen antibodies. Br J Haematol. 2001;114:245-246.
7. Hoffman. Expanding uses of high-dose factor VIIa. Blood. 2003;101:1666.
8. Monroe DM, Hoffman M, Allen GA, Roberts HR. The factor VII-platelet interplay: effectiveness of recombinant factor VIIa in the treatment of bleeding in severe thrombocytopathia. Semin Thromb Hemost. 2000;26:373-377.
9. Lisman T, Moschatsis S, Adelmeijer J, Nieuwenhuis HK, De Groot PG. Recombinant factor VIIa enhances deposition of platelets with congenital or acquired alpha IIbbeta 3 deficiency to endothelial cell matrix and collagen under conditions of flow via tissue factor-independent thrombin generation. Blood. 2003;101:1864-1870.