Pathways for glutamate biosynthesis in the yeast Kluyveromyces lactis

Microbiology

Volumn 146, Issue 1, 2000, Pages 239-245

  Romero, Mauricio ^a   Guzmán León, Simón ^a   Aranda, Cristina ^a   González Halphen, Diego ^a   Valenzuela, Lourdes ^a   González, Alicia ^a  

^a INSTITUTO DE FISIOLOGÍA CELULAR   (Mexico)

Author keywords

Glutamate biosynthesis; Glutamate dehydrogenase; Glutamate synthase

Indexed keywords

AMMONIA; GLUTAMATE SYNTHASE; GLUTAMIC ACID; NITRATE; OLIGODEOXYNUCLEOTIDE;

AMINO ACID SYNTHESIS; ARTICLE; CONTROLLED STUDY; CULTURE MEDIUM; ESCHERICHIA COLI; FUNGAL GENETICS; FUNGUS GROWTH; FUNGUS MUTANT; GENE CONSTRUCT; KLUYVEROMYCES; MAIZE; NONHUMAN; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

ESCHERICHIA COLI; EUKARYOTA; FUNGI; KLUYVEROMYCES LACTIS; MEDICAGO SATIVA; PROKARYOTA; ZEA MAYS;

EID: 0042407884     PISSN: 13500872     EISSN: None     Source Type: Journal    
DOI: 10.1099/00221287-146-1-239     Document Type: Article

References (40)

1. Adachi, K. & Suzuki, I. (1977). Purification and properties of glutamate synthase from Thiobacillus thioparus. J Bacterial 129, 1173-1182.
2. Anderson, M. P., Vance, C. P., Heichel, G. H. & Miller, S. S. (1989). Purification and characterization of NADH-glutamate synthase from alfalfa root nodules. Plant Physiol 90, 351-358.
3. Avendaño, A., DeLuna, A., Olivera, H., Valenzuela, L. & González, A. (1997). GDH3 encodes a glutamate dehydrogenase isozyme, a previously unrecognized route for glutamate biosynthesis in Saccharomyces cerevisiae. J Bacteriol 179, 5594-5597.
4. Barel, I. & MacDonald, D. W. (1993). Enzyme defects in glutamate-requiring strains of Schizosaccharomyces pombe. FEMS Microbiol Lett 113, 267-272.
5. Benny, A. G. & Boland, M. J. (1977). Enzymes of nitrogen metabolism in legume nodules. Purification and properties of NADH-dependent glutamate synthase from lupine nodules. Eur J Biochem 79, 355-362.
6. Bravo, A. & Mora, J. (1988). Ammonium assimilation in Rhizobium phaseoli by the glutamine synthetase-glutamate synthase pathway. J Bacteriol 170, 980-984.
7. Carlberg, I. & Nordlund, S. (1991). Purification and partial characterization of glutamate synthase from Rhodospirillum rubrum grown under nitrogen-fixing conditions. Biochem J 279, 151-154.
8. Chen, F. L. & Cullimore, J. V. (1988). Two isoenzymes of NADH-dependent glutamate synthase in root nodules of Phaseolus vulgaris L. Plant Physiol 88, 1411-1417.
9. Cogoni, C., Valenzuela, L., González-Halphen, D., Olivera, H., Macino, G., Ballario, P. & González, A. (1995). Saccharomyces cerevisiae has a single glutamate synthase gene coding for a plant-like high-molecular-weight polypeptide. J Bacteriol 177, 792-798.
10. Doherty, D. (1970). L-Glutamate dehydrogenases (yeast). Methods Enzymol 17, 850-856.
11. Gietz, R. D. & Woods, R. A. (1994). High efficiency transformation with lithium acetate. In Molecular Genetics of Yeast: a Practical Approach, pp. 121-134. Oxford: Oxford University Press.
12. Gonzalez, A., Membrillo-Hernández, J., Olivera, H., Aranda, C., Macino, G. & Ballario, P. (1992). Cloning of a yeast gene coding for the glutamate synthase small subunit (GVS2) by complementation of Saccharomyces cerevisiae and Escherichia coli glutamate auxotrophs. Mol Microbiol 6, 301-308.
13. González-Halphen. D., Lindorfer, M. A. & Capaldi, R. A. (1988). Subunit arrangement in beef heart complex III. Biochemistry 27, 7021-7031.
14. Hayakawa, T., Yamaya, T., Kamashi, K. & Ojima, K. (1992). Purification, characterization and immunological properties of NADH-dependent glutamate synthase from rice cell cultures. Plant Physiol 98, 1317-1322.
15. Helling, R. B. (1994). Why does Escherichia coli have two primary pathways for synthesis of glutamate? J Bacteriol 176, 4664-4668.
16. Holmes, A. R., Collings, A., Farnden, K. J. F. & Sheperd, M. G. (1989). Ammonium assimilation by Candida albicans and other yeasts: evidence for activity of glutamate synthase. J Gen Microbiol 135, 1423-1430.
17. Holzer, H. & Schneider, S. (1957). Anreicherung und Trennung einer DPN-spezifischen und einer TPN-spezifischen Glutaminosaure Dehydrogenase aus Hefe. Biochem Z 328, 361-367.
18. Hummelt, G. & Mora, J. (1980). Regulation and function of glutamate synthase in Neurospora crassa. Biochem Biophys Res Commun 96, 1688-1694.
19. Macheda, L., Hynes, M. J. & Davis, M. A. (1999). The Aspergillus nidulans gltA gene encoding glutamate synthase is required for ammonium assimilation in the absence of NADP-glutamate dehydrogenase. Curr Genet 34, 467-471.
20. Maniatis, T., Fritsch, E. F. & Sambrook, J. (1982) Molecular Cloning, a Laboratory Manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.
21. Marqués, S., Florencio, F. J. & Candau, P. (1992). Purification and characterization of the ferredoxin-glutamate synthase from the unicellular cyanohacterium Synecbococcus sp. PCC 6301. Eur J Biochem 206, 69-77.
22. Miflin, B. J., Lea, P. J. & Wallsgrove, R. M. (1980). The role of glutamine in ammonium assimilation and reassimilation in plants. In Glutamine: Metabolism, Enzymalogy and Regulation, pp. 213-234. Edited by J. Mora & R. Palacios. NY: Academic Press.
23. Miller, R. E. & Stadtman, E. R. (1972). Glutamate synthase from Escherichia coli. An iron-sulfide flavoprotein. J Biol Chem 247, 7407-7419.
24. Nasmyth, K. A. & Reed, S. I. (1980). Isolation of genes by complementation in yeast: molecular cloning of a cell-cycle gene. Proc Natl Acad Sci USA 77, 2119-2123.
25. Ratti, S., Curti, B., Zanetti, G. & Galli, E. (1985). Purification and characterization of glutamate synthase from Azospirillum brasilense. J Bacteriol 163, 724-729.
26. Romero, D. & Dávila, G. (1986). Genetic and biochemical identification of the glutamate synthase structural gene in Neurospora crassa. J Bacteriol 167, 1043-1047.
27. Roon, R. J., Even, H. L. & Larimore, F. (1974). Glutamate synthase: properties of the reduced nicotinamide adeninc dinucleotide-dependent enzyme from Saccharomyces cerevisiae. J Bacteriol 118, 89-95.
28. Schägger, H., Link, T. A., Engel, W. D. & von Jagow, G. (1986). Isolation of the eleven protein subunits of the be, complex from beef heart. Methods Enzymol 126, 224-237.
29. Schreier, H. J. & Bernlohr, R. W. (1984). Purification and properties of glutamate synthase from Bacillus licheniformis. J Bacteriol 160, 591-599.
30. Senior, P. J. (1975). Regulation of nitrogen metabolism in Escherichia coli and Klebstella aerogenes: studies with the continuous culture technique. J Bacteriol 123, 407-418.
31. Struhl, K. & Davis, R. W. (1981). Transcription of the his3 gene-region in Saccharomyces cerevisiae. J Mol Biol 152, 535-552.
32. Tempest, D. W., Meers, J. L. & Brown, C. M. (1970). Synthesis of glutamate in Aerobacter aerogenes by a hitherto unknown route. Biocbem J 117, 405-407.
33. Towbin, H., Staehelin, T. & Gordon, J. (1979). Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA 76, 4350-4354.
34. Trotta, P. P., Platzer, K. E. B., Haschemeyer, R. H. & Meister, A. (1974). Glutamine-binding subunit of glutamate synthase and partial reactions catalyzed by this glutamide amidotransferase. Proc Natl Acad Sci USA 71, 4607-4611.
35. Tyler, B. (1978). Regulation of the assimilation of nitrogen compounds. Annu Rev Biochem 47, 1127-1162.
36. Valenzuela, L., Guzmán-León, S., Coria, R., Ramírez, J., Aranda, C. & González, A. (1995). A NADP-glutamate dehydrogenase mutant of the petit-negative yeast Kluyveromyces lactis uses the glutamine synthethase-glutamate synthase pathway for glutamate biosynthesis. Microbiology 141, 2443-2447.
37. Valenzuela, L., Ballario, P., Aranda, C., Filetici, P. & González, A. (1998). Regulation of the expression of GLT1, the gene encoding glutamate synthase in Saccharomyces cerevisiae. J Bacteriol 180, 3533-3540.
38. Vanoni, M. A., Negri, A., Zanetti, G., Ronchi, S. & Curti, B. (1990). Structural studies on the subunits of glutamate synthase from Azospirillum brasilense. Biochim Biophys Acta 1039, 374-377.
39. Wach, A., Brachat, A., Pohlmann, R. & Philippsen, P. (1994). New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiae. Yeast 10, 1793-1808.
40. Wolfe, K. H. & Shields, D. C. (1997). Molecular evidence for an ancient duplication of the entire yeast genome. Nature 387, 708-713.