Lymphosarcoma-induced alterations in hepatic adrenergic receptors: Implications to the hypoglycemia of cancer cachexia

Molecular and Cellular Biochemistry

Volumn 250, Issue 1-2, 2003, Pages 167-177

  Hemmings, Susan J ^a   Wilson, Thomas R ^a  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

Author keywords

Cancer cachexia; Glucocounterregulation; Hepatic adrenergic receptors; Hypoglycemia; Lymphosarcoma; Thyroid hormone

Indexed keywords

ADRENERGIC RECEPTOR; ALPHA 1 ADRENERGIC RECEPTOR; ALPHA 2 ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR; GLUCAGON; GLUCOSE; INSULIN; THYROID HORMONE;

ANIMAL MODEL; ANIMAL TISSUE; CACHEXIA; CANCER CELL; CANCER GROWTH; CANCER STAGING; CANCER TRANSPLANTATION; CELL MEMBRANE; CONTROLLED STUDY; DEATH; FETUS LIVER; GLUCAGON BLOOD LEVEL; GLUCOSE BLOOD LEVEL; HYPOGLYCEMIA; INOCULATION; INSULIN BLOOD LEVEL; KINETICS; LIVER CELL MEMBRANE; LIVER INJURY; LYMPHOSARCOMA; NONHUMAN; PATHOGENESIS; RAT; RAT STRAIN; RECEPTOR AFFINITY; RECEPTOR BINDING; RECEPTOR DENSITY; REVIEW; STATISTICAL SIGNIFICANCE;

ALANINE TRANSAMINASE; ANIMALS; BLOOD GLUCOSE; CACHEXIA; CELL LINE, TUMOR; CELL MEMBRANE; FEMALE; GAMMA-GLUTAMYLTRANSFERASE; GLUCAGON; HYPOGLYCEMIA; KINETICS; LIVER; LYMPHOMA, DIFFUSE; PRAZOSIN; PROTEIN BINDING; RADIOIMMUNOASSAY; RATS; RATS, INBRED F344; RECEPTORS, ADRENERGIC; RECEPTORS, ADRENERGIC, ALPHA-1; THYROID HORMONES; TIME FACTORS;

ANIMALIA;

EID: 0042386049     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1024973908194     Document Type: Review

References (46)

1. Tisdale MJ: Biology of cachexia. J Natl Cancer Inst 89: 1763-1773, 1997
2. Tayek JA: A review of cancer cachexia and abnormal glucose metabolism in humans with cancer. J Am Coll Nutr 11: 445-456, 1992
3. Tisdale MJ: Metabolic abnormalities in cachexia and anorexia. Nutrition 16: 1013-1014, 2000
4. Keller U: Pathophysiology of cancer cachexia. Support Care Cancer 1: 290-294, 1993
5. Argiles JM, Meijsing SH, Pallares-Trujillo J, Guirao X, Lopez-Soriano FJ: Cancer cachexia: A therapeutic approach. Med Res Rev 21: 83-101, 2001
6. Emery PW, Carpenter TT, Obeid OA: Alterations in postprandial glycogen and lipid synthesis in cachectic tumor-bearing rats. Nutr Cancer 20: 231-240, 1993
7. Fujiki F, Mukaida N, Hirose K, Ishida H, Harada A, Ohno S, Bluethmann H, Kawakami M, Akiyama M, Sone S, Matsushima K: Prevention of adenocarcinoma colon 26-induced cachexia by interleukin 10 gene transfer. Cancer Res 57: 94-99, 1997
8. McDevitt TM, Tisdale MJ: Tumour-associated hypoglycaemia in a murine cachexia model. Br J Cancer 66: 815-820, 1992
9. Tamura S, Ouchi KF, Mori K, Endo M, Matsumoto T, Eda H, Tanaka Y, Ishitsuka H, Tokita H, Yamaguchi K: Involvement of human interleukin 6 in experimental cachexia induced by a human uterine cervical carcinoma xenograft. Clin Cancer Res 1: 1353-1358, 1995
10. Gerich JE: Physiology of glucose homeostasis. Diabetes Obes Metab 2: 345-350, 2000
11. Bolli GB, Fanelli CG: Physiology of glucose counterregulation to hypoglycemia. Endocrinol Metab Clin N Am 28: 467-493, 1999
12. Cryer PE: Hierarchy of physiological responses to hypoglycemia: Relevance to clinical hypoglycemia in type I (insulin dependent) diabetes mellitus. Horm Metab Res 29: 92-96, 1997
13. Schmelek PH, Hanoune J: The hepatic adrenergic receptors. Mol Cell Biochem 33: 35-48, 1980
14. Garcia-Sainz JA, Vazquez-Prado J, Villalobos-Molina R: Alpha 1-adrenoceptors: Subtypes, signaling, and roles in health and disease. Arch Med Res 30: 449-458, 1999
15. Lefkowitz RJ: The superfamily of heptahelical receptors. Nat Cell Biol 2: E133-136, 2000
16. Kimura M, Ogihara M: Expression of alpha2- and beta2-adrenergic responses by hepatocyte growth factor and platelet-derived growth factor in primary cultures of adult rat hepatocytes. Biol Pharm Bull 21: 22-28, 1998
17. Cardani R, Zavanella T: Immunohistochemical localization of beta 1-adrenergic receptors in the liver of male and female F344 rat. Histochem Cell Biol 116: 441-445, 2001
18. Minneman KP, Hedberg A, Molinoff PB: Comparison of beta adrenergic receptor subtypes in mammalian tissues. J Pharmacol Exp Ther 211: 502-508, 1979
19. Sulakhe SJ, Wilson TR: The impact of hypothyroidism and thyroxine replacement on the expression of hepatic alpha 1-, alpha 2- and beta-adrenergic receptors in rat liver plasma membranes. Gen Pharmacol 19: 489-494, 1988
20. Hemmings SJ, Spafford D: Neonatal STZ model of type II diabetes mellitus in the Fischer 344 rat: Characteristics and assessment of the status of the hepatic adrenergic receptors. Int J Biochem Cell Biol 32: 905-919, 2000
21. Sulakhe SJ: The activity of γ-glutamyltranspeptidase in regenerating rat liver. FEBS Lett 204: 302-306, 1986
22. Sulakhe SJ, Pulga VB, Tran S: Hepatic alpha 1 and beta adrenergic receptors in various animal species. Mol Cell Biochem 83: 81-88, 1988
23. Hemmings SJ, Storey KB: Alterations in hepatic adrenergic receptor status in Rana sylvatica in response to freezing and thawing: implications to the freeze-induced glycemic response. Can J Physiol Pharmacol 72: 1552-1560, 1994
24. Raabo E, Terkildsen TC: On the enzymatic determination of blood glucose. Scand J Clin Invest 12: 402, 1960
25. Reitman S, Frankel S: A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases. Am J Clin Path: 28: 53-56, 1957
26. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ: Protein measurement with the Folin phenol reagent. J Biol Chem: 193: 265-275, 1951
27. Michell RH, Hawthorne JN: The site of diphosphoinositide synthesis in rat liver. Biochem Biophys Res Commun 21: 333-338, 1965
28. Yamatani K, Saito K, Takahashi K, Ohnuma H, Manaka H, Sasaki H: Hormone-specific combinations of isoforms of adenylyl cyclase and phosphodiesterase in the rat liver. Regul Pept 99: 45-52, 2001
29. Thomas AP, Renard-Rooney DC, Hajnoczky G, Robb-Gaspers LD, Lin C, Rooney TA: Subcellular organization of calcium signalling in hepatocytes and the intact liver. Ciba Found Symp 188: 18-35; 35-49, 1995
30. Suh Y: Cell signaling in aging and apoptosis. Mech Ageing Dev 123: 881-890, 2002
31. Maitra SR, Wojnar MM, Lang CH: Alterations in tissue glucose uptake during the hyperglycemic and hypoglycemic phases of sepsis. Shock 13: 379-385, 2000
32. Dong LW, Yang J, Tong LJ, Tang C, Liu MS: Transcriptional regulation of alpha 1-adrenoceptor gene in the rat liver during different phases of sepsis. Biochim Biophys Acta. 1453: 207-215, 1999
33. Daza FJ, Parrilla R, Martin-Requero A: Influence of thyroid status on hepatic alpha 1-adrenoreceptor responsiveness. Am J Physiol 273: E1065-1072, 1997
34. 2+-independent, branch of the hepatic alpha 1-adrenoreceptor signalling pathway. Biochem J 331: 89-97, 1998
35. Vail DM, Panciera DL, Ogilvie GK: Thyroid hormone concentrations in dogs with chronic weight loss, with special reference to cancer cachexia. J Vet Intern Med 8: 122-127, 1994
36. Tancini G, Barni S, Crispino S, Paolorossi F, Lissoni P: A study of thyroid function in cancer cachexia. Tumori 75: 185-188, 1989
37. Hyltander A, Drott C, Korner U, Sandstrom R, Lundholm K: Elevated energy expenditure in cancer patients with solid tumours. Eur J Cancer 27: 9-15, 1991
38. Strassmann G, Kambayashi T: Inhibition of experimental cancer cachexia by anti-cytokine and anti-cytokine-receptor therapy. Cytokines Mol Ther 1: 107-113, 1995
39. Murayama-Oda K, Imamura K, Kim HK, Tanaka T: Mechanism of metabolic abnormality of thyroid hormones in Walker 256 carcinosarcoma-bearing rats. Jpn J Cancer Res 82: 98-108, 1991
40. Hemmings SJ: The Involvement of Plasma Membrane Bound Cyclic Nucleotide Enzyme Systems in Hepatic Ontogeny and Oncology. Saskatoon, Saskatchewan, 1980
41. Slotkin TA, Saleh JL, Zhang J, Seidler FJ: Ontogeny of beta-adrenoceptor/ adenylyl cyclase desensitization mechanisms: The role of neonatal innervation. Brain Res 742: 317-328, 1996
42. Shen H, Peri KG, Deng XF, Chemtob S, Varma DR: Distribution of alpha 1-adrenoceptor subtype proteins in different tissues of neonatal and adult rats. Can J Physiol Pharmacol 78: 237-243, 2000
43. Herzfeld A, Greengard O: The dedifferentiated pattern of enzymes in livers of tumor-bearing rats. Cancer Res 32: 1826-1832, 1972
44. Paxton K, Ward LC, Wilce PA: Amino acid oxidation in the tumor-bearing rat. Cancer Biochem Biophys 9: 343-351, 1988
45. Bartlett DL, Charland SL, Torosian MH: Reversal of tumor-associated hyperglucagonemia as treatment for cancer cachexia. Surgery 118: 87-97, 1995
46. Inculet RI, Peacock JL, Gorschboth CM, Norton JA: Gluconeogenesis in the tumor-influenced rat hepatocyte: Importance of tumor burden, lactate, insulin, and glucagon. J Natl Cancer Inst 79: 1039-1046, 1987