Pharmaceutical performance of solid dispersions containing poly(ethylene) glycol 6000 and diazepam or temazepam: Influence of grinding

Journal of Thermal Analysis and Calorimetry

Volumn 73, Issue 2, 2003, Pages 563-576

  Verheyen, S ^a   Blaton, N ^a   Kinget, R ^a   Van den Mooter, G ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Benzodiazepines; Dissolution; DSC; Grinding; Poly(ethylene) glycol; Solid dispersion; Stability; X ray powder diffraction

Indexed keywords

CRYSTALLIZATION; DIFFERENTIAL SCANNING CALORIMETRY; DISPERSIONS; GRINDING (MACHINING); POLYETHYLENE GLYCOLS; X RAY POWDER DIFFRACTION; CHEMICAL MODIFICATION; COOLING; DISSOLUTION; GEL PERMEATION CHROMATOGRAPHY; GLYCOLS; GRINDING (COMMINUTION); PARTICLE SIZE ANALYSIS; POLYETHYLENES; SOLUBILITY; SYNTHESIS (CHEMICAL);

SOLID DISPERSIONS; GELATIN CAPSULES;

DRUG PRODUCTS;

EID: 0042382993     PISSN: 13886150     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1025430213487     Document Type: Conference Paper

References (20)

1. W. L. Chiou and S. Riegelman, J. Pharm. Sci., 60 (1971) 1281.
2. C. Leuner and J. Dressman, Eur. J. Pharm., 50 (2000) 47.
3. J. L. Ford, Pharm. Acta Helv., 61 (1986) 69.
4. D. Q. M. Craig, Int. J. Pharm., 231 (2002) 131.
5. M. Bhattacharyya, S. K. Basu, B. K. Gupta, S. K. Ghosal, S. C. Mandal and S. C. Chattaraj, Drug Dev. Ind. Pharm., 19 (1993) 739.
6. F. Fawaz, F. Bonini, M. Guyot, J. Bildet, M. Maury and A. M. Lagueny, Int. J. Pharm., 132 (1996) 271.
7. G. Trapani, M. Franco, A. Latrofa, M. R. Pantaleo, M. R. Provenzano, E. Sanna, E. Maciocco and G. Liso, Int. J. Pharm., 184 (1999) 121.
8. N. Zerrouk, C. Chemtob, P. Arnaud, S. Toscani and J. Dugue, Int. J. Pharm., 225 (2001) 49.
9. S. K. Dordunoo, J. L. Ford and M. H. Rubinstein, Drug Dev. Ind. Pharm., 17 (1991) 1685.
10. S. K. Dordunoo, J. L. Ford and M. H. Rubinstein, J. Pharm. Pharmacol., 49 (1997) 390.
11. J. L. Ford and M. H. Rubinstein, Pharm. Acta Helv., 54 (1979) 353.
12. J. L. Ford and M. H. Rubinstein, Pharm. Acta Helv., 55 (1980) 1.
13. E. S. Saers, C. Nystrom and M. Alden, Int. J. Pharm., 90 (1993) 105.
14. S. Verheyen, N. Blaton, R. Kinget and G. Van den Mooter, Int. J. Pharm., 249 (2002) 45.
15. S. Verheyen, N. Blaton, R. Kinget and G. Van den Mooter, (2002) submitted.
16. C. P. Buckley and A. J. Kovacs, Progr. Colloid & Polymer Sci., 58 (1975) 44.
17. C. P. Buckley and A. J. Kovacs, Colloid & Polymer Sci., 254 (1976) 695.
18. S. Verheyen, P. Augustijns, R. Kinget and G. Van den Mooter, Thermochim. Acta, 380 (2001) 153.
19. G. A. Saleki, C. Ahlneck and G. Zografi, Int. J. Pharm., 101 (1994) 237.
20. G. Van den Mooter, J. Van den Brande, P. Augustijns and R. Kinget, J. Therm. Anal. Cal., 57 (1999) 493.