Analysis of the TGF-β1 promoter polymorphism (C - 509T) in patients with chronic periodontitis

Journal of Clinical Periodontology

Volumn 30, Issue 6, 2003, Pages 519-523

  De Souza, A P ^a   Trevilatto, P C ^a   Scarel Caminaga, R M ^a   De Brito Jr , R B ^a   Line, S R P ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

Chronic periodontitis severity; Polymorphism; Restriction enzyme; TGF 1

Indexed keywords

GENOMIC DNA; TRANSFORMING GROWTH FACTOR BETA1; CYTOSINE; TGFB1 PROTEIN, HUMAN; THYMINE; TRANSFORMING GROWTH FACTOR BETA;

ADULT; ALLELE; ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; MOUTH MUCOSA; PERIODONTITIS; POLYMERASE CHAIN REACTION; PROMOTER REGION; CASE CONTROL STUDY; CHRONIC DISEASE; GENE FREQUENCY; GENETIC MARKER; GENETICS; HOSPITALIZATION; PATHOLOGY; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; ALLELES; CASE-CONTROL STUDIES; CHRONIC DISEASE; CYTOSINE; FEMALE; GENE FREQUENCY; GENETIC MARKERS; HUMANS; MALE; MOUTH MUCOSA; PERIODONTITIS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS (GENETICS); SEVERITY OF ILLNESS INDEX; THYMINE; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1;

EID: 0042382903     PISSN: 03036979     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-051X.2003.00323.x     Document Type: Article

References (26)

1. Birkedal-Hansen, H. (1993) Role of matrix metalloproteinase in human periodontal diseases. Journal of Periodontology 64, 474-484.
2. Diehl, S. R., Wang, Y., Brooks, C. N., Burmeister, J. A., Califano, J. V., Wang, S. & Schenkein, H. A. (1999) Linkage disequilibrium of interleukin-1 genetic polymorphism with early-onset periodontitis. Journal of Periodontology 70, 418-430.
3. Engerbretson, S. P., Lamster, I. B., Herrera-Abreu, M., Celenti, R. S., Timms, J. M., Chaudhary, A. G. A., di Giovine, F. S. & Kornman, K. S. (1999) The influence of interleukin gene polymorphism on expression of interleukin-1β and tumor necrosis factor-α in periodontal tissue and gingival crevicular fluid. Journal of Periodontology 70, 567-573.
4. Flemmig, T.F (1999) Periodontitis. In Genco, R. J. & Armitage, G. C., eds. Annals of Periodontology (International Workshop for a Classification of Periodontal Diseases and Conditions) 4, 32-41.
5. Genco, R. J. (1992) Host responses in periodontal diseases: current concepts. Journal of Periodontology 63, 338-355.
6. +3953 allele 2: association with disease status in adult periodontitis. Journal of Clinical Periodontology 25, 781-785.
7. Grainger, D. J., Heathcote, K., Chiano, M., Snieder, H., Kemp, P. R., Metcalfe, J. C., Carter, N. D. & Spector, T. D. (1999) Genetic control of the circulating concentration of transforming growth factor type beta 1. Human Molecular Genetic 8, 93-97.
8. Hennig, B. J. W., Parkhill, J. M., Chapple, I. L. C., Heasman, P. A. & Taylor, J. J. (1999) Association of a vitamin D receptor gene polymorphism with localized early-onset periodontal diseases. Journal of Periodontology 70, 1032-1038.
9. Hobbs, K., Negri, J., Klinnert, M., Rosenwasser L, . J. & Borish L, . (1998) Interleukin-10 and transforming growth factor-β promoter polymorphisms in allergies and asthma. American Journal of Critical Care Medicine 158, 1958-1962.
10. Kim, S. J., Glick, A., Sporn, M. B. & Roberts, A. B. (1989) Characterization of the promoter region of the human transforming growth factor-β1 gene. Journal of Biological Chemistry 264, 402-408.
11. Kornman, K. S., Crane, A., Wang, H. Y., di Giovine, F. S., Newman, M. G., Pirk, F. W., Wilson, T. G. Jr., Higginbottom, F. L. & Duff, G. W. (1997) The interleukin-1 genotype as a severity factor in adult periodontal disease. Journal of Clinical Periodontology 24, 72-77.
12. Michalowicz, B. S., Diehl, S. R., Gunsolley, J. C., Sparks, B. S., Brooks, C. N., Koertge, T. E., Califano, J. V., Burmeister, J. A. & Schenkein, H. A. (2000) Evidence of a substantial genetic basis for risk of adult periodontitis. Journal of Periodontology 71, 1699-1707.
13. Morse, H. R., Olomolaiye, O. O., Wood, N. A. P., Keen, L. J. & Bidwell, J. L. (1999) Induced heteroduplex genotyping of TNF-α, IL-1β, IL-6 and IL-10 polymorphisms associated with transcriptional regulation. Cytokine 11, 789-795.
14. Musso, T., Espinoza-Delgado, I., Pulkki, K., Gusella, G. L., Longo, D. L. & Varesio, L. (1990) Transforming Growth Factor β down-regulates interleukin-1 (IL-1)-induced IL-6 production by human monocytes. Blood 76, 2466-2469.
15. Overall, C. M., Wrana, J. L. & Sodek, J. (1991) Induction of formative and resorptive cellular phenotypes in human gingival fibroblasts by TGF-β1 and concanavalin A: regulation of matrix metalloproteinase and TIMP. Journal of Periodontal Research 26, 279-282.
16. Page, R. C. (1992) Host response tests for diagnosing periodontal diseases. Journal of Periodontology 63, 356-366.
17. Shrivastava, A. & Calame, K. (1994) An analysis of genes regulated by the multi-function transcriptional regulatory Yin Yang-1. Nucleic Acids Research 24, 5151-5155.
18. Socransky, S. S., Haffajee, A. D., Smith, C. & Duff, G. W. (2000) Microbiological parameters associated with IL-1 gene polymorphisms in periodontitis patients. Journal of Clinical Periodontology 27, 810-818.
19. 1 in chronically-inflamed periodontal tissue. Journal of Clinical Periodontology 26, 366-373.
20. Syrris, P., Carter, N. D., Metcalfe, J. C., Kemp, P. R., Grainger, D. J., Kaski, J. C., Crossman, D. C., Francis, S. E., Gunn, J., Jeffery, S. & Heathcote, K. (1998) Transforming growth factor-beta 1 gene polymorphism and coronary artery disease. Clinical Science (Colch) 95, 659-667.
21. Trevilatto, P. C. & Line, S. R. P. (2000) Use of buccal epithelial cells for PCR amplification of large DNA fragments. Journal of Forensic Odonto-Stomatology 18, 6-9.
22. Trevilatto, P. C., Tramontina, V. A., Machado, M. A. N., Gonçalves, R. B., Sallum, A. W. & Line, S. R. P. (2002) Clinical, genetic and microbiological findings in a Brazilian family with aggressive periodontitis. Journal of Clinical Periodontology 29, 233-239.
23. Wahl, S. M. (1992) TGF-β in inflammation. A cause and a cure. Journal of Clinical Immunology 12, 1-14.
24. Wahl, S. M., Costa, G. L., Mizel, D. E., Allen, J. B., Skaleric, U. & Mangan, D. F. (1993) Role of transforming growth factor beta in the pathophysiology of chronic inflammation. Journal of Periodontology 64, 450-455.
25. Wilton, J. M. A., Bampton, J. L. M., Griffiths, G. S., Curtis, M. A., Life, J. S., Johnson, N. W., Powell, J. R., Harrap, G. J. & Critchley, P. (1992) Interleukin-1 beta (IL-1β) levels in gingival crevicular fluid from adults with previous evidence of destructive periodontitis - a cross sectional study. Journal of Clinical Periodontology 19, 53-57.
26. Yamada, Y., Miyauchi, A., Takagi, Y., Tanaka, M., Mizuno, M. & Harada, A. (2001) Association of the C - 509 → T polymorphism, alone or in combination with the T869 → C polymorphism, of the transforming growth factor-beta1 gene with bone mineral density and genetic susceptibility to osteoporosis in Japanese women. Journal of Molecular Medicine 79, 149-156.