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1
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0033673757
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Thorson, J. S.; Sievers, E. L.; Ahlert, J.; Shepard, E.; Whitwam, R. E.; Onwueme, K. C.; Ruppen, M. Curr. Pharm. Des. 2000. 6, 1841-1879.
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Thorson, J.S.1
Sievers, E.L.2
Ahlert, J.3
Shepard, E.4
Whitwam, R.E.5
Onwueme, K.C.6
Ruppen, M.7
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3
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0023689095
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The first suggestion, based on the distance between the ends of the alkyne units ("cd" distance), is useful only for simple monocyclic systems: Nicolaou, K. C.; Zuccarello, G.; Ogawa, Y.; Schweiger, E. J.; Kumazawa, T. J. Am. Chem. Soc. 1988, 110, 4866-4868.
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Nicolaou, K.C.1
Zuccarello, G.2
Ogawa, Y.3
Schweiger, E.J.4
Kumazawa, T.5
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4
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5344278331
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Strain energy (MM) analysis has been used in more complex frameworks related to the natural products: Magnus, P.; Fortt, S.; Pitterna, T.; Snyder, J. P. J. Am. Chem. Soc. 1990, 112, 4986-4987.
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J. Am. Chem. Soc.
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Magnus, P.1
Fortt, S.2
Pitterna, T.3
Snyder, J.P.4
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5
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0037047550
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-
DFT calculations have been reported recently for enediyne cyclizations: (a) Jones, G. B.; Wright, J. M.; Hynd, G.; Wyatt, J. K.; Warner, P. M.; Huber, R. S.; Li, A.; Kilgore, M. W.; Sticca, R. P.; Pollenz, R. S. J. Org. Chem. 2002, 67, 5727-5732.(b) Ahlstrom, B.; Kraka, E.; Cremer, D. Chem. Phys. Lett. 2002, 361, 129-135. (c) Prall, M.; Wittkopp, A.; Schreiner, P. R. J. Phys. Chem. A 2001, 105, 9265-9274.
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J. Org. Chem.
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Jones, G.B.1
Wright, J.M.2
Hynd, G.3
Wyatt, J.K.4
Warner, P.M.5
Huber, R.S.6
Li, A.7
Kilgore, M.W.8
Sticca, R.P.9
Pollenz, R.S.10
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6
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0037167117
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DFT calculations have been reported recently for enediyne cyclizations: (a) Jones, G. B.; Wright, J. M.; Hynd, G.; Wyatt, J. K.; Warner, P. M.; Huber, R. S.; Li, A.; Kilgore, M. W.; Sticca, R. P.; Pollenz, R. S. J. Org. Chem. 2002, 67, 5727-5732.(b) Ahlstrom, B.; Kraka, E.; Cremer, D. Chem. Phys. Lett. 2002, 361, 129-135. (c) Prall, M.; Wittkopp, A.; Schreiner, P. R. J. Phys. Chem. A 2001, 105, 9265-9274.
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(2002)
Chem. Phys. Lett.
, vol.361
, pp. 129-135
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Ahlstrom, B.1
Kraka, E.2
Cremer, D.3
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7
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0035846423
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DFT calculations have been reported recently for enediyne cyclizations: (a) Jones, G. B.; Wright, J. M.; Hynd, G.; Wyatt, J. K.; Warner, P. M.; Huber, R. S.; Li, A.; Kilgore, M. W.; Sticca, R. P.; Pollenz, R. S. J. Org. Chem. 2002, 67, 5727-5732.(b) Ahlstrom, B.; Kraka, E.; Cremer, D. Chem. Phys. Lett. 2002, 361, 129-135. (c) Prall, M.; Wittkopp, A.; Schreiner, P. R. J. Phys. Chem. A 2001, 105, 9265-9274.
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(2001)
J. Phys. Chem. A
, vol.105
, pp. 9265-9274
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Prall, M.1
Wittkopp, A.2
Schreiner, P.R.3
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9
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0032490113
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For discussion, see Schreiner, P. R. J. Am. Chem. Soc. 1998, 120, 4184-4190. Density functional calculations were performed using GAUSSIAN 98; the built-in default thresholds for wave function and gradient convergence were employed; transition state structures were located by using the QST3 option and verified by frequency calculations.
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(1998)
J. Am. Chem. Soc.
, vol.120
, pp. 4184-4190
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Schreiner, P.R.1
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10
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0041394819
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Ph.D. Dissertation, Princeton University
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Sarpong, R. Ph.D. Dissertation, Princeton University, 2001.
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(2001)
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Sarpong, R.1
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11
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0042397018
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Based on reports by the following: (a) Belleau, B.; Dvornik, D. Can J. Chem. 1965, 43, 2545-2550. (b) Kobayashi, S.; Eguchi, Y.; Shimada, M.; Ohno, M. Chem. Pharm. Bull. 1990, 38, 1479-1484.
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(1965)
Can J. Chem.
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, pp. 2545-2550
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Belleau, B.1
Dvornik, D.2
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12
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0024986564
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Based on reports by the following: (a) Belleau, B.; Dvornik, D. Can J. Chem. 1965, 43, 2545-2550. (b) Kobayashi, S.; Eguchi, Y.; Shimada, M.; Ohno, M. Chem. Pharm. Bull. 1990, 38, 1479-1484.
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Chem. Pharm. Bull.
, vol.38
, pp. 1479-1484
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Kobayashi, S.1
Eguchi, Y.2
Shimada, M.3
Ohno, M.4
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13
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0042897959
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note
-
N2 displacement with several carbon nucleophiles was not successful.
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-
-
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14
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0041394818
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note
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The configurations of the substitution products 10 were established for 10 (X, Y = Cl) via X-ray analysis and conversion to common intermediate 11.
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-
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15
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0033549583
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Bertrand, F.; Quiclet-Sire, B.; Zard, S. Z. Angew. Chem., Int. Ed. 1999, 38, 1943-1946.
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Angew. Chem., Int. Ed.
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Bertrand, F.1
Quiclet-Sire, B.2
Zard, S.Z.3
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16
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0001517035
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Brown, D. G.; Velthuisen, E. J.; Commerford, J. R.; Brisbois, R. G.; Hoye, T. R. J. Org. Chem. 1996, 61, 2540-2541.
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(1996)
J. Org. Chem.
, vol.61
, pp. 2540-2541
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Brown, D.G.1
Velthuisen, E.J.2
Commerford, J.R.3
Brisbois, R.G.4
Hoye, T.R.5
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19
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0041394816
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note
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The structure of 16 was confirmed by an X-ray diffraction study.
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21
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0025130379
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Wender, P. A.; McKinney, J. A.; Mukai, C. J. Am. Chem. Soc. 1990, 112, 5369-5370.
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Wender, P.A.1
McKinney, J.A.2
Mukai, C.3
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22
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9644285669
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Sonogashira, K.; Tohda, Y.; Hagihara, N. Tetrahedron Lett. 1975, 16, 4467-4470.
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(1975)
Tetrahedron Lett.
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Sonogashira, K.1
Tohda, Y.2
Hagihara, N.3
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23
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0042897953
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note
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1H NMR spectrum, but serious line broadening left greater uncertainty in the values.
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