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Volumn 125, Issue 35, 2003, Pages 10496-10497

Conformational control in activation of an enediyne

Author keywords

[No Author keywords available]

Indexed keywords

ALKENYLDIALKYNE DERIVATIVE; ALKYNE DERIVATIVE; UNCLASSIFIED DRUG;

EID: 0042355731     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja036763e     Document Type: Article
Times cited : (20)

References (23)
  • 6
    • 0037167117 scopus 로고    scopus 로고
    • DFT calculations have been reported recently for enediyne cyclizations: (a) Jones, G. B.; Wright, J. M.; Hynd, G.; Wyatt, J. K.; Warner, P. M.; Huber, R. S.; Li, A.; Kilgore, M. W.; Sticca, R. P.; Pollenz, R. S. J. Org. Chem. 2002, 67, 5727-5732.(b) Ahlstrom, B.; Kraka, E.; Cremer, D. Chem. Phys. Lett. 2002, 361, 129-135. (c) Prall, M.; Wittkopp, A.; Schreiner, P. R. J. Phys. Chem. A 2001, 105, 9265-9274.
    • (2002) Chem. Phys. Lett. , vol.361 , pp. 129-135
    • Ahlstrom, B.1    Kraka, E.2    Cremer, D.3
  • 7
    • 0035846423 scopus 로고    scopus 로고
    • DFT calculations have been reported recently for enediyne cyclizations: (a) Jones, G. B.; Wright, J. M.; Hynd, G.; Wyatt, J. K.; Warner, P. M.; Huber, R. S.; Li, A.; Kilgore, M. W.; Sticca, R. P.; Pollenz, R. S. J. Org. Chem. 2002, 67, 5727-5732.(b) Ahlstrom, B.; Kraka, E.; Cremer, D. Chem. Phys. Lett. 2002, 361, 129-135. (c) Prall, M.; Wittkopp, A.; Schreiner, P. R. J. Phys. Chem. A 2001, 105, 9265-9274.
    • (2001) J. Phys. Chem. A , vol.105 , pp. 9265-9274
    • Prall, M.1    Wittkopp, A.2    Schreiner, P.R.3
  • 9
    • 0032490113 scopus 로고    scopus 로고
    • For discussion, see Schreiner, P. R. J. Am. Chem. Soc. 1998, 120, 4184-4190. Density functional calculations were performed using GAUSSIAN 98; the built-in default thresholds for wave function and gradient convergence were employed; transition state structures were located by using the QST3 option and verified by frequency calculations.
    • (1998) J. Am. Chem. Soc. , vol.120 , pp. 4184-4190
    • Schreiner, P.R.1
  • 10
    • 0041394819 scopus 로고    scopus 로고
    • Ph.D. Dissertation, Princeton University
    • Sarpong, R. Ph.D. Dissertation, Princeton University, 2001.
    • (2001)
    • Sarpong, R.1
  • 11
    • 0042397018 scopus 로고
    • Based on reports by the following: (a) Belleau, B.; Dvornik, D. Can J. Chem. 1965, 43, 2545-2550. (b) Kobayashi, S.; Eguchi, Y.; Shimada, M.; Ohno, M. Chem. Pharm. Bull. 1990, 38, 1479-1484.
    • (1965) Can J. Chem. , vol.43 , pp. 2545-2550
    • Belleau, B.1    Dvornik, D.2
  • 13
    • 0042897959 scopus 로고    scopus 로고
    • note
    • N2 displacement with several carbon nucleophiles was not successful.
  • 14
    • 0041394818 scopus 로고    scopus 로고
    • note
    • The configurations of the substitution products 10 were established for 10 (X, Y = Cl) via X-ray analysis and conversion to common intermediate 11.
  • 19
    • 0041394816 scopus 로고    scopus 로고
    • note
    • The structure of 16 was confirmed by an X-ray diffraction study.
  • 23
    • 0042897953 scopus 로고    scopus 로고
    • note
    • 1H NMR spectrum, but serious line broadening left greater uncertainty in the values.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.